Neda Zamani,Görel Sundström,Marc P Höppner et al.
Neda Zamani et al.
Background: The fundamental challenge in optimally aligning homologous sequences is to define a scoring scheme that best reflects the underlying biological processes. Maximising the overall number of matches in the alignm...
BatTool: an R package with GUI for assessing the effect of White-nose syndrome and other take events on Myotis spp. of bats [0.03%]
BatTool：一个用于评估白鼻综合症和其他捕获事件对Myotis蝙蝠属物种影响的R语言软件包及图形用户界面
Richard A Erickson,Wayne E Thogmartin,Jennifer A Szymanski
Richard A Erickson
Background: Myotis species of bats such as the Indiana Bat and Little Brown Bat are facing population declines because of White-nose syndrome (WNS). These species also face threats from anthropogenic activities such as wi...
Software for pre-processing Illumina next-generation sequencing short read sequences [0.03%]
用于预处理Illumina下一代测序短读序列的软件
Chuming Chen,Sari S Khaleel,Hongzhan Huang et al.
Chuming Chen et al.
Background: When compared to Sanger sequencing technology, next-generation sequencing (NGS) technologies are hindered by shorter sequence read length, higher base-call error rate, non-uniform coverage, and platform-specif...
H3Africa: a tipping point for a revolution in bioinformatics, genomics and health research in Africa [0.03%]
非洲生物信息学、基因组学和健康研究革命的转折点:H3Africa项目
Moses P Adoga,Segun A Fatumo,Simon M Agwale
Moses P Adoga
Background: A multi-million dollar research initiative involving the National Institutes of Health (NIH), Wellcome Trust and African scientists has been launched. The initiative, referred to as H3Africa, is an acronym tha...
BLASTPLOT: a PERL module to plot next generation sequencing NCBI-BLAST results [0.03%]
BLASTPLOT：一个绘制基于NCBI的下一代测序BLAST结果的PERL模块
Jesus Enrique Herrera-Galeano,Kenneth G Frey,Regina Z Cer et al.
Jesus Enrique Herrera-Galeano et al.
Background: The development of Next Generation Sequencing (NGS) during the last decade has created an unprecedented amount of sequencing data, as well as the ability to rapidly sequence specimens of interest. Read-based B...
Kuruvilla Joseph Abraham,Clara Diaz
Kuruvilla Joseph Abraham
Background: Genetic Analyses in large sample populations are important for a better understanding of the variation between populations, for designing conservation programs, for detecting rare mutations which may be risk f...
PFClust: an optimised implementation of a parameter-free clustering algorithm [0.03%]
PFClust：参数无用聚类算法的优化实现
Khadija Musayeva,Tristan Henderson,John Bo Mitchell et al.
Khadija Musayeva et al.
Background: A well-known problem in cluster analysis is finding an optimal number of clusters reflecting the inherent structure of the data. PFClust is a partitioning-based clustering algorithm capable, unlike many widely...
Correction: Dispelling myths about rare disease registry system development [0.03%]
罕见病注册系统建设的几个误区纠正意见
Matthew Bellgard,Christophe Beroud,Kay Parkinson et al.
Matthew Bellgard et al.
Published Erratum
Source code for biology and medicine. 2014 Jan 31;9(1):4. DOI:10.1186/1751-0473-9-4 2014
ROVER variant caller: read-pair overlap considerate variant-calling software applied to PCR-based massively parallel sequencing datasets [0.03%]
ROVER变异调用器：应用于基于PCR的大规模并行序列数据的读对重叠考虑型变异调用软件
Bernard J Pope,Tú Nguyen-Dumont,Fleur Hammet et al.
Bernard J Pope et al.
Background: We recently described Hi-Plex, a highly multiplexed PCR-based target-enrichment system for massively parallel sequencing (MPS), which allows the uniform definition of library size so that subsequent paired-end...
Luís Paquete,Pedro Matias,Maryam Abbasi et al.
Luís Paquete et al.
: Multiobjective sequence alignment brings the advantage of providing a set of alignments that represent the trade-off between performing insertion/deletions and matching symbols from both sequences. Each of these alignments provide a poten...