Robust dose-response curve estimation applied to high content screening data analysis [0.03%]
用于高内涵筛选数据分析的稳健剂量效应曲线估计方法
Thuy Tuong Nguyen,Kyungmin Song,Yury Tsoy et al.
Thuy Tuong Nguyen et al.
Background and method: Successfully automated sigmoidal curve fitting is highly challenging when applied to large data sets. In this paper, we describe a robust algorithm for fitting sigmoid dose-response curves by estima...
Erratum: BatTool: an R package with GUI for assessing the effect of white-nose syndrome and other take events on Myotis spp. of bats [0.03%]
致歉：BatTool：一个用于评估白鼻综合症和其他取样事件对鼠类蝙蝠种群影响的R语言软件包及其图形用户界面
Richard A Erickson,Wayne E Thogmartin,Jennifer A Szymanski
Richard A Erickson
[This corrects the article DOI: 10.1186/1751-0473-9-9.].
Published Erratum
Source code for biology and medicine. 2014 Dec 20;9(1):122. DOI:10.1186/s13029-014-0028-9 2014
Onco-STS: a web-based laboratory information management system for sample and analysis tracking in oncogenomic experiments [0.03%]
基于网络的实验室信息系统 Onco-STS：在肿瘤基因组实验中的样品和分析追踪系统
Mike Gavrielides,Simon J Furney,Tim Yates et al.
Mike Gavrielides et al.
Background: Whole genomes, whole exomes and transcriptomes of tumour samples are sequenced routinely to identify the drivers of cancer. The systematic sequencing and analysis of tumour samples, as well other oncogenomic e...
HeatmapGenerator: high performance RNAseq and microarray visualization software suite to examine differential gene expression levels using an R and C++ hybrid computational pipeline [0.03%]
Heatmap生成器：使用R和C++混合计算管线检测差异表达基因的高性能RNA seq及微阵列图像化软件套件
Bohdan B Khomtchouk,Derek J Van Booven,Claes Wahlestedt
Bohdan B Khomtchouk
Background: The graphical visualization of gene expression data using heatmaps has become an integral component of modern-day medical research. Heatmaps are used extensively to plot quantitative differences in gene expres...
Methylation plotter: a web tool for dynamic visualization of DNA methylation data [0.03%]
DNA甲基化数据的动态可视化网络工具
Izaskun Mallona,Anna Díez-Villanueva,Miguel A Peinado
Izaskun Mallona
Methylation plotter is a Web tool that allows the visualization of methylation data in a user-friendly manner and with publication-ready quality. The user is asked to introduce a file containing the methylation status of a genomic region. T...
Aleksey Porollo
Aleksey Porollo
Background: Next-generation sequencing and metagenome projects yield a large number of new genomes that need further annotations, such as identification of enzymes and metabolic pathways, or analysis of metabolic strategi...
Michel Petitjean,Anne Vanet
Michel Petitjean
Background: For over 400 years, due to the reassortment of their segmented genomes, influenza viruses evolve extremely quickly and cause devastating epidemics. This reassortment arises because two flu viruses can infect t...
Easyworm: an open-source software tool to determine the mechanical properties of worm-like chains [0.03%]
易虫：一种测定蠕虫链状物机械特性的开源软件工具
Guillaume Lamour,Julius B Kirkegaard,Hongbin Li et al.
Guillaume Lamour et al.
Background: A growing spectrum of applications for natural and synthetic polymers, whether in industry or for biomedical research, demands for fast and universally applicable tools to determine the mechanical properties o...
A dedicated database system for handling multi-level data in systems biology [0.03%]
一个用于处理系统生物学中多层次数据的专用数据库系统
Natapol Pornputtapong,Kwanjeera Wanichthanarak,Avlant Nilsson et al.
Natapol Pornputtapong et al.
Background: Advances in high-throughput technologies have enabled extensive generation of multi-level omics data. These data are crucial for systems biology research, though they are complex, heterogeneous, highly dynamic...
Matthew I Bellgard,Lee Render,Maciej Radochonski et al.
Matthew I Bellgard et al.
Background: Information management systems are essential to capture data be it for public health and human disease, sustainable agriculture, or plant and animal biosecurity. In public health, the term patient registry is ...