Matthew Carr,Cait E MacPhee
Matthew Carr
Background: The study of biological membranes using Molecular Dynamics has become an increasingly popular means by which to investigate the interactions of proteins, peptides and potentials with lipid bilayers. These inte...
Damien M O&#x;Halloran
Damien M O&#x;Halloran
Background: High-throughput primer design is routinely performed in a wide number of molecular applications including genotyping specimens using traditional PCR techniques as well as assembly PCR, nested PCR, and primer w...
Three algorithms and SAS macros for estimating power and sample size for logistic models with one or more independent variables of interest in the presence of covariates [0.03%]
三个算法和SAS宏命令用于在存在协变量的情况下估计一个或多个感兴趣自变量的逻辑模型的功效和样本量估算
David Keith Williams,Zoran Bursac
David Keith Williams
Background: Commonly when designing studies, researchers propose to measure several independent variables in a regression model, a subset of which are identified as the main variables of interest while the rest are retain...
popRange: a highly flexible spatially and temporally explicit Wright-Fisher simulator [0.03%]
popRange：一种高度灵活的具有时空显式的wright-fisher模拟器
Kimberly F McManus
Kimberly F McManus
Background: Sequencing and genotyping technology advancements have led to massive, growing repositories of spatially explicit genetic data and increasing quantities of temporal data (i.e., ancient DNA). These data will al...
Wormpath: searching for molecular interaction networks in Caenorhabditis elegans [0.03%]
Wormpath：在秀丽隐杆线虫中的分子相互作用网络搜索
Peter Frommolt,Björn Schumacher
Peter Frommolt
Background: High-throughput transcriptional profiling using Next-Generation Sequencing (RNA-Seq) or microarray technology have become standard tools in molecular biology. Successful investigations of gene regulatory mecha...
MagiCMicroRna: a web implementation of AgiMicroRna using shiny [0.03%]
MagiCMicroRna：使用Shiny实现AgiMicroRna的Web版本
Maarten Lj Coonen,Daniel Hj Theunissen,Jos Cs Kleinjans et al.
Maarten Lj Coonen et al.
Background: MicroRNA expression can be quantified using sequencing techniques or commercial microRNA-expression arrays. Recently, the AgiMicroRna R-package was published that enabled systematic preprocessing and statistic...
LocusTrack: Integrated visualization of GWAS results and genomic annotation [0.03%]
LocusTrack：集成了基因组注释的GWAS结果可视化工具
Gabriel Cuellar-Partida,Miguel E Renteria,Stuart MacGregor
Gabriel Cuellar-Partida
Background: Genome-wide association studies (GWAS) are an important tool for the mapping of complex traits and diseases. Visual inspection of genomic annotations may be used to generate insights into the biological mechan...
Mega2: validated data-reformatting for linkage and association analyses [0.03%]
mega2：经验证的用于连锁和关联分析的数据重组软件
Robert V Baron,Charles Kollar,Nandita Mukhopadhyay et al.
Robert V Baron et al.
Background: In a typical study of the genetics of a complex human disease, many different analysis programs are used, to test for linkage and association. This requires extensive and careful data reformatting, as many of ...
Timothy D O&#x;Connor
Timothy D O&#x;Connor
Motivation: Correctly modeling population structure is important for understanding recent evolution and for association studies in humans. While pre-existing knowledge of population history can be used to specify expected...
Using the value of Lin's concordance correlation coefficient as a criterion for efficient estimation of areas of leaves of eelgrass from noisy digital images [0.03%]
以线氏一致性相关系数的价值为标准，有效估计海带叶片噪声数字图像的区域
Héctor Echavarría-Heras,Cecilia Leal-Ramírez,Enrique Villa-Diharce et al.
Héctor Echavarría-Heras et al.
Background: Eelgrass is a cosmopolitan seagrass species that provides important ecological services in coastal and near-shore environments. Despite its relevance, loss of eelgrass habitats is noted worldwide. Restoration ...