TagDigger: user-friendly extraction of read counts from GBS and RAD-seq data [0.03%]
TagDigger：从GBS和RAD-seq数据中提取读取计数的用户友好型工具
Lindsay V Clark,Erik J Sacks
Lindsay V Clark
Background: In genotyping-by-sequencing (GBS) and restriction site-associated DNA sequencing (RAD-seq), read depth is important for assessing the quality of genotype calls and estimating allele dosage in polyploids. Howev...
A new tool for prioritization of sequence variants from whole exome sequencing data [0.03%]
一种新的工具可优先处理全外显子组测序数据中的序列变异体
Brigitte Glanzmann,Hendri Herbst,Craig J Kinnear et al.
Brigitte Glanzmann et al.
Background: Whole exome sequencing (WES) has provided a means for researchers to gain access to a highly enriched subset of the human genome in which to search for variants that are likely to be pathogenic and possibly pr...
Log::ProgramInfo: A Perl module to collect and log data for bioinformatics pipelines [0.03%]
用于收集和记录生物信息学流水线数据的Perl模块Log::ProgramInfo
John M Macdonald,Paul C Boutros
John M Macdonald
Background: To reproduce and report a bioinformatics analysis, it is important to be able to determine the environment in which a program was run. It can also be valuable when trying to debug why different executions are ...
SV-STAT accurately detects structural variation via alignment to reference-based assemblies [0.03%]
基于参考基因组组装的定位准确检测结构变异软件SV-STAT
Caleb F Davis,Deborah I Ritter,David A Wheeler et al.
Caleb F Davis et al.
Background: Genomic deletions, inversions, and other rearrangements known collectively as structural variations (SVs) are implicated in many human disorders. Technologies for sequencing DNA provide a potentially rich sour...
Implementation and clinical application of a deformation method for fast simulation of biological tissue formed by fibers and fluid [0.03%]
一种快速模拟纤维和流体构成的生物组织变形方法及其临床应用
Ana Gabriella de Oliveira Sardinha,Ceres Nunes de Resende Oyama,Armando de Mendonça Maroja et al.
Ana Gabriella de Oliveira Sardinha et al.
Background: The aim of this paper is to provide a general discussion, algorithm, and actual working programs of the deformation method for fast simulation of biological tissue formed by fibers and fluid. In order to demon...
MM2S: personalized diagnosis of medulloblastoma patients and model systems [0.03%]
MM2S：髓母细胞瘤患者和模型系统的个性化诊断
Deena M A Gendoo,Benjamin Haibe-Kains
Deena M A Gendoo
Background: Medulloblastoma (MB) is a highly malignant and heterogeneous brain tumour that is the most common cause of cancer-related deaths in children. Increasing availability of genomic data over the last decade had re...
A flexible tool to plot a genomic map for single nucleotide polymorphisms [0.03%]
一种用于单核苷酸多态性基因组图谱绘制的灵活工具
Fuquan Zhang
Fuquan Zhang
Background: Most genetic association studies use single-nucleotide polymorphisms (SNPs) as the research targets. However, resources to visualize the genomic map of candidate SNPs in a programming manner are limited. We ha...
A generic schema and data collection forms applicable to diverse entomological studies of mosquitoes [0.03%]
适用于各种蚊虫研究的通用表格和数据收集表
Samson S Kiware,Tanya L Russell,Zacharia J Mtema et al.
Samson S Kiware et al.
Background: Standardized schemas, databases, and public data repositories are needed for the studies of malaria vectors that encompass a remarkably diverse array of designs and rapidly generate large data volumes, often i...
Conserved antigenic sites between MERS-CoV and Bat-coronavirus are revealed through sequence analysis [0.03%]
序列分析揭示了MERS-CoV和蝙蝠冠状病毒具有的保守抗原位点
Refat Sharmin,Abul B M M K Islam
Refat Sharmin
Background: MERS-CoV is a newly emerged human coronavirus reported closely related with HKU4 and HKU5 Bat coronaviruses. Bat and MERS corona-viruses are structurally related. Therefore, it is of interest to estimate the d...
Implementation of the Rank-Weighted Co-localization (RWC) algorithm in multiple image analysis platforms for quantitative analysis of microscopy images [0.03%]
在多个图像分析平台中实现Rank-Weighted Co-localization (RWC)算法用于定量分析显微镜图像
Vasanth R Singan,Jeremy C Simpson
Vasanth R Singan
Background: Quantitative co-localization studies strengthen the analysis of fluorescence microscopy-based assays and are essential for illustrating and understanding many cellular processes and interactions. In our earlie...