FLIM-FRET analyzer: open source software for automation of lifetime-based FRET analysis [0.03%]
一种基于寿命型FRET分析的自动化开源软件FLIM-FRET分析仪
Jiho Kim,Yury Tsoy,Jan Persson et al.
Jiho Kim et al.
Background: Despite the broad use of FRET techniques, available methods for analyzing protein-protein interaction are subject to high labor and lack of systematic analysis. We propose an open source software allowing the ...
goSTAG: gene ontology subtrees to tag and annotate genes within a set [0.03%]
用于一组基因标记和注释的gene ontology子树gostag
Brian D Bennett,Pierre R Bushel
Brian D Bennett
Background: Over-representation analysis (ORA) detects enrichment of genes within biological categories. Gene Ontology (GO) domains are commonly used for gene/gene-product annotation. When ORA is employed, often times the...
Jörn Bethune,Lars Kraemer,Ingo Thomsen et al.
Jörn Bethune et al.
Background: In science peer-reviewed publications serve as an important indicator of scientific excellence and productivity. Therefore, every scientist and institution must carefully maintain and update records of their s...
NET: a new framework for the vectorization and examination of network data [0.03%]
Net：网络数据向量化的全新框架与研究
Jana Lasser,Eleni Katifori
Jana Lasser
Background: The analysis of complex networks both in general and in particular as pertaining to real biological systems has been the focus of intense scientific attention in the past and present. In this paper we introduc...
Algorithm and software to automatically identify latency and amplitude features of local field potentials recorded in electrophysiological investigation [0.03%]
用于自动识别局部场电位记录的延迟和幅度特征的算法和软件
Maria Rubega,Claudia Cecchetto,Stefano Vassanelli et al.
Maria Rubega et al.
Background: Local field potentials (LFPs) evoked by sensory stimulation are particularly useful in electrophysiological research. For instance, spike timing and current transmembrane current flow estimated from LFPs recor...
DEApp: an interactive web interface for differential expression analysis of next generation sequence data [0.03%]
DEApp：下一代序列数据差异表达分析的交互式网络界面
Yan Li,Jorge Andrade
Yan Li
Background: A growing trend in the biomedical community is the use of Next Generation Sequencing (NGS) technologies in genomics research. The complexity of downstream differential expression (DE) analysis is however still...
Syed Haider,Daryl Waggott,Emilie Lalonde et al.
Syed Haider et al.
[This corrects the article DOI: 10.1186/s13029-016-0059-5.].
Published Erratum
Source code for biology and medicine. 2017 Jan 9:12:1. DOI:10.1186/s13029-016-0061-y 2017
Syed Haider,Daryl Waggott,Emilie Lalonde et al.
Syed Haider et al.
Background: Next-generation sequencing is making it critical to robustly and rapidly handle genomic ranges within standard pipelines. Standard use-cases include annotating sequence ranges with gene or other genomic annota...
PureCN: copy number calling and SNV classification using targeted short read sequencing [0.03%]
利用目标短串联测序进行拷贝数呼叫和SNV分类
Markus Riester,Angad P Singh,A Rose Brannon et al.
Markus Riester et al.
Background: Matched sequencing of both tumor and normal tissue is routinely used to classify variants of uncertain significance (VUS) into somatic vs. germline. However, assays used in molecular diagnostics focus on known...
cljam: a library for handling DNA sequence alignment/map (SAM) with parallel processing [0.03%]
CLJAM：一种用于处理DNA序列对齐/地图（SAM）的并行处理库
Toshiki Takeuchi,Atsuo Yamada,Takashi Aoki et al.
Toshiki Takeuchi et al.
Background: Next-generation sequencing can determine DNA bases and the results of sequence alignments are generally stored in files in the Sequence Alignment/Map (SAM) format and the compressed binary version (BAM) of it....