Pharmacodynamic Effect of Different Dosage Regimes of Oseltamivir in Severe Influenza Patients Requiring Mechanical Ventilation: A Multicentre Randomised Controlled Trial [0.03%]
不同剂量奥司他韦对重症流感机械通气患者药效学影响的多中心随机对照试验
Wai-Tat Wong,Gordon Choi,Xiansong Wang et al.
Wai-Tat Wong et al.
Background and objectives: This randomised controlled trial evaluated whether higher doses of oseltamivir would improve virological and clinical outcomes in severe influenza patients requiring invasive mechanical ventilat...
Randomized Controlled Trial
Influenza and other respiratory viruses. 2025 May;19(5):e70109. DOI:10.1111/irv.70109 2025
Unveiling the Spectrum of Respiratory Syncytial Virus Disease in Adults: From Community to Hospital [0.03%]
成人呼吸道合胞病毒疾病的谱系：从社区到医院
Koos Korsten,Matthijs R A Welkers,Thijs van de Laar et al.
Koos Korsten et al.
Background: Respiratory syncytial virus can cause severe disease in the older adult population. Three vaccines for RSV are currently market approved but the risk of RSV-hospitalization in (older) adults from a community l...
Low Levels of Neutralizing Antibodies Against SARS-CoV-2 KP.3.1.1 and XEC in Serum From Seniors in May 2024 [0.03%]
2024年5月老年人血液中针对SARS-CoV-2 KP.3.1.1和XEC的中和抗体水平较低
Even Fossum,Elisabeth Lea Vikse,Anna Hayman Robertson et al.
Even Fossum et al.
New immune evasive variants of SARS-CoV-2 may increase infections and hospitalizations in risk groups, such as the elderly. In this study, we evaluated neutralizing antibodies against KP.3.1.1 and XEC, virus variants that were either widely...
Molecular Evolution of Influenza A Viruses From Mauritius, 2017-2019 [0.03%]
毛里求斯2017-2019年流感病毒的分子进化研究
Magalutcheemee Ramuth,Janaki Sonoo,Fhooblall Mokshanand et al.
Magalutcheemee Ramuth et al.
Background: Despite being a vaccine preventable disease, influenza remains a burden in African countries. In Mauritius, influenza virus activity is year-round but evidence-based data to guide vaccination and pandemic prep...
Impact of Nirsevimab on RSV and Non-RSV Severe Respiratory Infections in Hospitalized Infants [0.03%]
nirsevimab对住院婴儿呼吸道合胞病毒和其他病原体导致的下呼吸道感染的影响
María Luz García-García,Patricia Alonso-López,Sonia Alcolea et al.
María Luz García-García et al.
Background: Nirsevimab, a monoclonal antibody providing passive immunity against RSV infections in infants, was introduced in Spain in October 2023 for children under 6 months and those born during the epidemic season. Th...
An Improved Rapid and Sensitive Long Amplicon Method for Nanopore-Based RSV Whole-Genome Sequencing [0.03%]
一种改进的基于纳米孔测序技术进行RSV全基因组测序的长片段快速灵敏扩增方法
Xiaomin Dong,Steven Edwards,Yi-Mo Deng et al.
Xiaomin Dong et al.
Background: Whole-genome sequencing (WGS) provides critical insights into the respiratory syncytial virus (RSV) transmission and any emerging mutations that could impair the efficacy of monoclonal antibodies or vaccines t...
General Population and Healthcare Professionals' Level of Knowledge of the Burden and Prevention of Respiratory Syncytial Virus in France [0.03%]
法国居民和医疗专业人员对呼吸道合胞病毒负担及预防知识水平的研究
Joshua Puel,Katia Sosnowiez,Robin Stephan et al.
Joshua Puel et al.
Estimated Incidence Rate of Specific Types of Cardiovascular and Respiratory Hospitalizations Attributable to Respiratory Syncytial Virus Among Adults in Germany Between 2015 and 2019 [0.03%]
2015年至2019年德国成人特定类型的心血管和呼吸系统住院病例的呼吸道合胞病毒归因发病率估算
Caihua Liang,Aleksandra Polkowska-Kramek,Caroline Lade et al.
Caihua Liang et al.
Background: RSV incidence in adults is frequently underestimated due to non-specific symptomatology, limited standard-of-care testing, and lower test sensitivity compared to infants. We conducted a retrospective observati...
Observational Study
Influenza and other respiratory viruses. 2025 May;19(5):e70097. DOI:10.1111/irv.70097 2025
The Role of Viral Interference in Shaping RSV Epidemics Following the 2009 H1N1 Influenza Pandemic [0.03%]
病毒干扰在2009年甲型H1N1流感大流行后塑造RSV流行中的作用
Ke Li,Deus Thindwa,Daniel M Weinberger et al.
Ke Li et al.
Background: Disruptions in respiratory syncytial virus (RSV) activity were observed in different countries following the 2009 influenza pandemic. Given the limited use of non-pharmaceutical interventions, these disruption...
Epidemiological Shifts in Children Respiratory Pathogens in Shenzhen, China: A Comparative Analysis Before and After the Relaxation of COVID-19 Non-Pharmaceutical Interventions [0.03%]
中国深圳新冠肺炎非药物干预措施调整前后儿童呼吸道病原体的流行特征比较分析
Heping Wang,Yuping Guo,Rongjun Wang et al.
Heping Wang et al.
Background: The COVID-19 pandemic and associated non-pharmaceutical interventions significantly altered the epidemiology of respiratory pathogens. This study aimed to evaluate the changes in the prevalence and distributio...
Comparative Study
Influenza and other respiratory viruses. 2025 Apr;19(4):e70114. DOI:10.1111/irv.70114 2025