Dpr10 and Nocte are required for Drosophila motor axon pathfinding [0.03%]
Dpr10和Nocte是果蝇运动神经元轴突导航所必需的
Meike Lobb-Rabe,Katherine DeLong,Rio J Salazar et al.
Meike Lobb-Rabe et al.
The paths axons travel to reach their targets and the subsequent synaptic connections they form are highly stereotyped. How cell surface proteins (CSPs) mediate these processes is not completely understood. The Drosophila neuromuscular junc...
mRNAs encoding neurodevelopmental regulators have equal N6-methyladenosine stoichiometry in Drosophila neuroblasts and neurons [0.03%]
神经发育调节因子编码的mRNA在果蝇神经干细胞和神经元中具有相同的N6-甲基腺苷浓度
Josephine D Sami,Robert C Spitale,Michael D Cleary
Josephine D Sami
N6-methyladenosine (m6A) is the most prevalent internal mRNA modification in metazoans and is particularly abundant in the central nervous system. The extent to which m6A is dynamically regulated and whether m6A contributes to cell type-spe...
Single cell RNA-seq analysis reveals temporally-regulated and quiescence-regulated gene expression in Drosophila larval neuroblasts [0.03%]
单细胞RNA测序分析揭示了果蝇幼虫神经干细胞性质调节和静息调节的基因表达
Noah Dillon,Ben Cocanougher,Chhavi Sood et al.
Noah Dillon et al.
The mechanisms that generate neural diversity during development remains largely unknown. Here, we use scRNA-seq methodology to discover new features of the Drosophila larval CNS across several key developmental timepoints. We identify mult...
A single-cell transcriptomic atlas of complete insect nervous systems across multiple life stages [0.03%]
跨越多个生命阶段的完整昆虫神经系统的单细胞转录组图谱
Marc Corrales,Benjamin T Cocanougher,Andrea B Kohn et al.
Marc Corrales et al.
Molecular profiles of neurons influence neural development and function but bridging the gap between genes, circuits, and behavior has been very difficult. Here we used single cell RNAseq to generate a complete gene expression atlas of the ...
Early development of the cochlea of the common marmoset, a non-human primate model [0.03%]
常见狨猴耳蜗早期发育的研究——非人灵长类动物模型
Makoto Hosoya,Masato Fujioka,Junko Okahara et al.
Makoto Hosoya et al.
Background: Fine-tuned cochlear development is essential for hearing. Owing to the difficulty in using early human fetal samples, most of our knowledge regarding cochlear development has been obtained from rodents. Howeve...
DSCAM is differentially patterned along the optic axon pathway in the developing Xenopus visual system and guides axon termination at the target [0.03%]
视黄酸视觉系统中的DSCAM沿光学轴突路径形成动态表达模式并引导轴突在靶处停止生长
Rommel Andrew Santos,Rodrigo Del Rio Jr,Alexander Delfin Alvarez et al.
Rommel Andrew Santos et al.
Background: The Xenopus retinotectal circuit is organized topographically, where the dorsal-ventral axis of the retina maps respectively on to the ventral-dorsal axis of the tectum; axons from the nasal-temporal axis of t...
Correction to: Loss of Neuropilin2a/b or Sema3fa alters olfactory sensory axon dynamics and protoglomerular targeting [0.03%]
Correction to: Neuropilin2a/b或Sema3fa的丧失改变了嗅觉感觉轴突动力学和原神经节样体靶向作用
Ryan P Cheng,Puneet Dang,Alemji A Taku et al.
Ryan P Cheng et al.
Published Erratum
Neural development. 2022 Mar 5;17(1):4. DOI:10.1186/s13064-022-00160-w 2022
Enhancer of trithorax/polycomb, Corto, regulates timing of hunchback gene relocation and competence in Drosophila neuroblasts [0.03%]
果蝇神经干细胞中Corto调控hunchback基因重定位及潜能的时机选择
Terry L Hafer,Sofiya Patra,Daiki Tagami et al.
Terry L Hafer et al.
Background: Neural progenitors produce diverse cells in a stereotyped birth order, but can specify each cell type for only a limited duration. In the Drosophila embryo, neuroblasts (neural progenitors) specify multiple, d...
A subpopulation of astrocyte progenitors defined by Sonic hedgehog signaling [0.03%]
sonic hedgehog信号定义的一群星形胶质细胞前体细胞亚群
Ellen C Gingrich,Kendra Case,A Denise R Garcia
Ellen C Gingrich
Background: The molecular signaling pathway, Sonic hedgehog (Shh), is critical for the proper development of the central nervous system. The requirement for Shh signaling in neuronal and oligodendrocyte development in the...
Loss of Neuropilin2a/b or Sema3fa alters olfactory sensory axon dynamics and protoglomerular targeting [0.03%]
Neuropilin2a/b或Sema3fa的丧失影响嗅觉感觉轴突动态和原神经节芽靶向性
Ryan P Cheng,Puneet Dang,Alemji A Taku et al.
Ryan P Cheng et al.
Background: Olfactory Sensory Neuron (OSN) axons project from the zebrafish olfactory epithelium to reproducible intermediate target locations in the olfactory bulb called protoglomeruli at early stages in development. Tw...