E-proteins orchestrate the progression of neural stem cell differentiation in the postnatal forebrain [0.03%]
E蛋白在产后脑前体神经干细胞分化进程中的作用机制研究
Bruno Fischer,Kasum Azim,Anahí Hurtado-Chong et al.
Bruno Fischer et al.
Background: Neural stem cell (NSC) differentiation is a complex multistep process that persists in specific regions of the postnatal forebrain and requires tight regulation throughout life. The transcriptional control of ...
Axon-Schwann cell interactions during peripheral nerve regeneration in zebrafish larvae [0.03%]
斑马鱼幼体外周神经再生过程中的轴突-施万细胞相互作用
Maria Laura Ceci,Camila Mardones-Krsulovic,Mario Sánchez et al.
Maria Laura Ceci et al.
Background: Peripheral nerve injuries can severely affect the way that animals perceive signals from the surrounding environment. While damage to peripheral axons generally has a better outcome than injuries to central ne...
Genetic dissection of TrkB activated signalling pathways required for specific aspects of the taste system [0.03%]
TrkB激活的信号通路在特定味觉系统方面的遗传解剖学研究
Juraj Koudelka,Jacqueline M Horn,Chinnavuth Vatanashevanopakorn et al.
Juraj Koudelka et al.
Background: Neurotrophin-4 (NT-4) and brain derived neurotrophic factor (BDNF) bind to the same receptor, Ntrk2/TrkB, but play distinct roles in the development of the rodent gustatory system. However, the mechanisms unde...
Dbx1b defines the dorsal habenular progenitor domain in the zebrafish epithalamus [0.03%]
Dbx1b定义斑马鱼前脑背侧habenula前体细胞区域
Benjamin J Dean,Begum Erdogan,Joshua T Gamse et al.
Benjamin J Dean et al.
Background: The conserved habenular nuclei function as a relay system connecting the forebrain with the brain stem. They play crucial roles in various cognitive behaviors by modulating cholinergic, dopaminergic and seroto...
Spinal neurons require Islet1 for subtype-specific differentiation of electrical excitability [0.03%]
Islet1对脊髓神经元电兴奋性分化的亚型特异性要求不可或缺
Rosa L Moreno,Angeles B Ribera
Rosa L Moreno
Background: In the spinal cord, stereotypic patterns of transcription factor expression uniquely identify neuronal subtypes. These transcription factors function combinatorially to regulate gene expression. Consequently, ...
Optix defines a neuroepithelial compartment in the optic lobe of the Drosophila brain [0.03%]
Optix定义了果蝇大脑视叶中的神经上皮区室
Katrina S Gold,Andrea H Brand
Katrina S Gold
Background: During early brain development, the organisation of neural progenitors into a neuroepithelial sheet maintains tissue integrity during growth. Neuroepithelial cohesion and patterning is essential for orderly pr...
Pioneer midbrain longitudinal axons navigate using a balance of Netrin attraction and Slit repulsion [0.03%]
净rin吸引和裂隙排斥的平衡引导先驱中脑纵向轴突导航
Minkyung Kim,W Todd Farmer,Brielle Bjorke et al.
Minkyung Kim et al.
Background: Longitudinal axons grow parallel to the embryonic midline to connect distant regions of the central nervous system. Previous studies suggested that repulsive midline signals guide pioneer longitudinal axons by...
Nuclei-specific differences in nerve terminal distribution, morphology, and development in mouse visual thalamus [0.03%]
小鼠视觉丘脑中不同神经核的终末分布、形态和发育的特异性差异
Sarah Hammer,Gabriela L Carrillo,Gubbi Govindaiah et al.
Sarah Hammer et al.
Background: Mouse visual thalamus has emerged as a powerful model for understanding the mechanisms underlying neural circuit formation and function. Three distinct nuclei within mouse thalamus receive retinal input, the d...
The neurotrophin receptor p75 regulates gustatory axon branching and promotes innervation of the tongue during development [0.03%]
神经生长因子受体p75调节味觉轴突侧支的形成并促进舌发育过程中的神经支配
Da Fei,Tao Huang,Robin F Krimm
Da Fei
Background: Brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT4) regulate the survival of gustatory neurons, axon growth and branching, and innervation of taste buds during development. These actions are larg...
Transcriptional control of GABAergic neuronal subtype identity in the thalamus [0.03%]
丘脑中GABA能神经元亚型身份的转录调控
Katherine Sellers,Verena Zyka,Andrew G Lumsden et al.
Katherine Sellers et al.
Background: The thalamus is often defined as the 'gateway to consciousness', a feature that is supported by the specific connectivity and electrophysiological properties of its neurons. Inhibitory GABAergic neurons are re...