Type I intrinsically photosensitive retinal ganglion cells of early post-natal development correspond to the M4 subtype [0.03%]
发育早期的视网膜固有感光节细胞神经元对应于M4亚型
Timothy J Sexton,Adam Bleckert,Maxwell H Turner et al.
Timothy J Sexton et al.
Background: Intrinsically photosensitive retinal ganglion cells (ipRGCs) mediate circadian light entrainment and the pupillary light response in adult mice. In early development these cells mediate different processes, in...
Erratum to: Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones [0.03%]
erratum ：生长锥中引导物诱导的局部蛋白质合成对F-肌动蛋白和微管细胞骨架的不同需求
Michael Piper,Aih Cheun Lee,Francisca P G van Horck et al.
Michael Piper et al.
Published Erratum
Neural development. 2015 Jun 19:10:16. DOI:10.1186/s13064-015-0043-9 2015
Multi-site phosphorylation regulates NeuroD4 activity during primary neurogenesis: a conserved mechanism amongst proneural proteins [0.03%]
泛神经发生过程中多磷酸化调节NeuroD4活性：原神经蛋白中的保守机制
Laura J A Hardwick,Anna Philpott
Laura J A Hardwick
Background: Basic Helix Loop Helix (bHLH) proneural transcription factors are master regulators of neurogenesis that act at multiple stages in this process. We have previously demonstrated that multi-site phosphorylation ...
Netrin-1 directs dendritic growth and connectivity of vertebrate central neurons in vivo [0.03%]
Netrin-1指导脊椎动物中枢神经元的树突生长和连接
Anastasia N Nagel,Sonya Marshak,Colleen Manitt et al.
Anastasia N Nagel et al.
Background: Netrins are a family of extracellular proteins that function as chemotropic guidance cues for migrating cells and axons during neural development. In the visual system, netrin-1 has been shown to play a key ro...
The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex [0.03%]
甲基结合域3/核小体重塑和去乙酰化复合体调节大脑皮质神经元的细胞命运决定及终末分化
Erin Knock,João Pereira,Patrick D Lombard et al.
Erin Knock et al.
Background: Chromatin-modifying complexes have key roles in regulating various aspects of neural stem cell biology, including self-renewal and neurogenesis. The methyl binding domain 3/nucleosome remodelling and deacetyla...
Genetic chimeras reveal the autonomy requirements for Vsx2 in embryonic retinal progenitor cells [0.03%]
基因嵌合体揭示了Vsx2在胚胎视网膜祖细胞中的自主性要求
Crystal L Sigulinsky,Massiell L German,Amanda M Leung et al.
Crystal L Sigulinsky et al.
Background: Vertebrate retinal development is a complex process, requiring the specification and maintenance of retinal identity, proliferative expansion of retinal progenitor cells (RPCs), and their differentiation into ...
Dana A Burow,Maxine C Umeh-Garcia,Marie B True et al.
Dana A Burow et al.
Background: Gene expression patterns are determined by rates of mRNA transcription and decay. While transcription is known to regulate many developmental processes, the role of mRNA decay is less extensively defined. A cr...
Fgf signaling controls the telencephalic distribution of Fgf-expressing progenitors generated in the rostral patterning center [0.03%]
FGF信号控制在rostro patterning中心产生的FGF表达前体在整个端脑内的分布
Renée V Hoch,Jeffrey A Clarke,John L R Rubenstein
Renée V Hoch
Background: The rostral patterning center (RPC) secretes multiple fibroblast growth factors (Fgfs) essential for telencephalon growth and patterning. Fgf expression patterns suggest that they mark functionally distinct RP...
Subrepellent doses of Slit1 promote Netrin-1 chemotactic responses in subsets of axons [0.03%]
Slit1的部分排斥剂量可促进Netrin-1在轴突亚群中的化学趋向性反应
Isabelle Dupin,Ludmilla Lokmane,Maxime Dahan et al.
Isabelle Dupin et al.
Background: Axon pathfinding is controlled by guidance cues that elicit specific attractive or repulsive responses in growth cones. It has now become clear that some cues such as Netrin-1 can trigger either attraction or ...
Upregulation of the zebrafish Nogo-A homologue, Rtn4b, in retinal ganglion cells is functionally involved in axon regeneration [0.03%]
拟齿鱼类Nogo-A同源物Rtn4b在视网膜节细胞中的上调表达对其轴突再生具有功能作用
Cornelia Welte,Sarah Engel,Claudia A O Stuermer
Cornelia Welte
Background: In contrast to mammals, zebrafish successfully regenerate retinal ganglion cell (RGC) axons after optic nerve section (ONS). This difference is explained on the one hand by neurite growth inhibitors in mammals...