Ephrin-A2 and ephrin-A5 guide contralateral targeting but not topographic mapping of ventral cochlear nucleus axons [0.03%]
Ephrin-A2和ephrin-A5指导腹侧耳蜗核轴突的对侧支配但不能指导其拓扑映射
Mariam L Abdul-Latif,Jesus A Ayala Salazar,Sonya Marshak et al.
Mariam L Abdul-Latif et al.
Background: In the auditory brainstem, ventral cochlear nucleus (VCN) axons project to the contralateral, but not ipsilateral, medial nucleus of trapezoid body (MNTB), terminating in the calyx of Held. Dorsal VCN neurons,...
Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons [0.03%]
Pax6被背侧丘脑神经元前体细胞内在需要，用于正常分子模式的形成但并非轴突生长和引导所需的因子
James M Clegg,Ziwen Li,Michael Molinek et al.
James M Clegg et al.
Background: In mouse embryos, the Pax6 transcription factor is expressed in the progenitors of thalamic neurons but not in thalamic neurons themselves. Its null-mutation causes early mis-patterning of thalamic progenitors...
EphrinB2 sharpens lateral motor column division in the developing spinal cord [0.03%]
EphrinB2促进发育中脊髓侧运动柱的分化
Maëva Luxey,Julien Laussu,Alice Davy
Maëva Luxey
Background: During sensori-motor circuit development, the somas of motoneurons (MN) are distributed in a topographic manner in the ventral horn of the neural tube. Indeed, their position within the lateral motor columns (...
An emerging role for prdm family genes in dorsoventral patterning of the vertebrate nervous system [0.03%]
PRDM家族基因在脊椎动物神经系统背腹模式形成中的作用初探
Denise A Zannino,Charles G Sagerström
Denise A Zannino
The embryonic vertebrate neural tube is divided along its dorsoventral (DV) axis into eleven molecularly discrete progenitor domains. Each of these domains gives rise to distinct neuronal cell types; the ventral-most six domains contribute ...
The LRR receptor Islr2 is required for retinal axon routing at the vertebrate optic chiasm [0.03%]
LRR受体Islr2在脊椎动物视交叉处的视网膜轴突引导中是必需的
Paolo Panza,Austen A Sitko,Hans-Martin Maischein et al.
Paolo Panza et al.
Background: In the visual system of most binocular vertebrates, the axons of retinal ganglion cells (RGCs) diverge at the diencephalic midline and extend to targets on both ipsi- and contralateral sides of the brain. Whil...
Erratum to: Morphogenesis underlying the development of the everted teleost telencephalon [0.03%]
有关鱼类外翻大脑发育形态发生的修正意见
Mónica Folgueira,Philippa Bayley,Pavla Navratilova et al.
Mónica Folgueira et al.
Published Erratum
Neural development. 2015 Oct 2:10:22. DOI:10.1186/s13064-015-0048-4 2015
Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems [0.03%]
Rac1在中枢和外周神经系统轴突生长、导向及神经元存活中起重要作用
Zhong L Hua,Francesco E Emiliani,Jeremy Nathans
Zhong L Hua
Background: Rac1 is a critical regulator of cytoskeletal dynamics in multiple cell types. In the nervous system, it has been implicated in the control of cell proliferation, neuronal migration, and axon development. ...
Developmental attenuation of N-methyl-D-aspartate receptor subunit expression by microRNAs [0.03%]
微小核糖核酸对N-甲基-D-天门冬氨酸受体亚单位表达的发育性减弱作用
Caroline Corbel,Israel Hernandez,Bian Wu et al.
Caroline Corbel et al.
Background: N-methyl-D-aspartate receptors (NMDARs) are a subtype of ionotropic glutamate receptors and are expressed throughout the central nervous system (CNS). Their activity is required for excitatory synaptic transmi...
Developmental remodeling of relay cells in the dorsal lateral geniculate nucleus in the absence of retinal input [0.03%]
视网膜输入缺失情况下外侧膝状体背侧部中继神经元的重塑发展过程
Rana N El-Danaf,Thomas E Krahe,Emily K Dilger et al.
Rana N El-Danaf et al.
Background: The dorsal lateral geniculate nucleus (dLGN) of the mouse has been an important experimental model for understanding thalamic circuit development. The developmental remodeling of retinal projections has been t...
A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors [0.03%]
RBM8a在胚胎神经前体细胞增殖和分化中的关键作用
Donghua Zou,Colleen McSweeney,Aswathy Sebastian et al.
Donghua Zou et al.
Background: Nonsense mediated mRNA decay (NMD) is an RNA surveillance mechanism that controls RNA stability and ensures the speedy degradation of erroneous and unnecessary transcripts. This mechanism depends on several co...