Olfactory sensory axons target specific protoglomeruli in the olfactory bulb of zebrafish [0.03%]
斑马鱼嗅觉感觉轴突在嗅球中 targeting 特殊的原嗅小球
Xin Shao,Vanisha Lakhina,Puneet Dang et al.
Xin Shao et al.
Background: The axons of Olfactory Sensory Neurons (OSNs) project to reproducible target locations within the Olfactory Bulb (OB), converting odorant experience into a spatial map of neural activity. We characterized the ...
Mariko Ogawa,Fuminori Saitoh,Norihiro Sudou et al.
Mariko Ogawa et al.
Background: Cyclin-dependent kinase (CDK) inhibitors play an important role in regulating cell cycle progression, cell cycle exit and cell differentiation. p27KIP1 (p27), one of the major CDK inhibitors in the retina, has...
Prdm13 forms a feedback loop with Ptf1a and is required for glycinergic amacrine cell genesis in the Xenopus Retina [0.03%]
Prdm13与Ptf1a互为反馈调控并在非洲爪蟾视网膜甘氨酸胺能神经元的产生中必不可少
Nathalie Bessodes,Karine Parain,Odile Bronchain et al.
Nathalie Bessodes et al.
Background: Amacrine interneurons that modulate synaptic plasticity between bipolar and ganglion cells constitute the most diverse cell type in the retina. Most are inhibitory neurons using either GABA or glycine as neuro...
Two Drosophila model neurons can regenerate axons from the stump or from a converted dendrite, with feedback between the two sites [0.03%]
两个果蝇模型神经元可以从切口处或从转换的树突中再生轴突，并且两处之间存在反馈作用
Kavitha S Rao,Melissa M Rolls
Kavitha S Rao
Background: After axon severing, neurons recover function by reinitiating axon outgrowth. New outgrowth often originates from the remaining axon stump. However, in many mammalian neurons, new axons initiate from a dendrit...
Septal contributions to olfactory bulb interneuron diversity in the embryonic mouse telencephalon: role of the homeobox gene Gsx2 [0.03%]
哺乳动物胚胎脑前叶中嗅球中间神经元多样性形成的机制及Gsx2同源盒基因的作用
Shenyue Qin,Stephanie M Ware,Ronald R Waclaw et al.
Shenyue Qin et al.
Background: Olfactory bulb (OB) interneurons are known to represent diverse neuronal subtypes, which are thought to originate from a number of telencephalic regions including the embryonic dorsal lateral ganglionic eminen...
Neocortical Sox9+ radial glia generate glutamatergic neurons for all layers, but lack discernible evidence of early laminar fate restriction [0.03%]
新皮层Sox9阳性放射状胶质细胞产生所有层的谷氨酸能神经元，但缺乏明显的早期层定位限制证据
E S Kaplan,K A Ramos-Laguna,A B Mihalas et al.
E S Kaplan et al.
Glutamatergic neurons in the cerebral cortex are derived from embryonic neural stem cells known as radial glial progenitors (RGPs). Early RGPs, present at the onset of cortical neurogenesis, are classically thought to produce columnar clone...
Fate bias during neural regeneration adjusts dynamically without recapitulating developmental fate progression [0.03%]
神经再生过程中的命运偏向动态调节而不会重现发育过程中的命运进展
Jeremy Ng Chi Kei,Peter David Currie,Patricia Regina Jusuf
Jeremy Ng Chi Kei
Background: Regeneration of neurons in the central nervous system is poor in humans. In other vertebrates neural regeneration does occur efficiently and involves reactivation of developmental processes. Within the neural ...
Marcela Lipovsek,Julia Ledderose,Thomas Butts et al.
Marcela Lipovsek et al.
Background: The cells of the mesencephalic trigeminal nucleus (MTN) are the proprioceptive sensory neurons that innervate the jaw closing muscles. These cells differentiate close to the two key signalling centres that inf...
Eph/Ephrin Signaling Controls Progenitor Identities In The Ventral Spinal Cord [0.03%]
Eph/ephrin信号传导控制脊髓腹侧祖细胞的身份
Julien Laussu,Christophe Audouard,Anthony Kischel et al.
Julien Laussu et al.
Background: In the vertebrate spinal cord, motor neurons (MN) are generated in stereotypical numbers from a pool of dedicated progenitors (pMN) whose number depends on signals that control their specification but also the...
Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals [0.03%]
顶叶发育过程中半球中间带的重塑作用仅存在于真兽类哺乳动物中
Ilan Gobius,Rodrigo Suárez,Laura Morcom et al.
Ilan Gobius et al.
The corpus callosum forms the major interhemispheric connection in the human brain and is unique to eutherian (or placental) mammals. The developmental events associated with the evolutionary emergence of this structure, however, remain poo...