Integrating peritumor and tumor CT radiomics features in predicting local control after SBRT in patients with pulmonary oligometastases [0.03%]
结合立体定向放疗后肺寡转移瘤患者瘤内和瘤周CT影像组学特征预测局部控制概率
Yao Lu,Yiqi Wang,Yuxi Ding et al.
Yao Lu et al.
Purpose: Local control prediction for patients with pulmonary oligometastases underwent stereotactic body radiotherapy (SBRT) is crucial for optimizing therapeutic strategies. This study aims to develop and validate a pre...
CBCT-based online adaptive radiotherapy of the bladder - geometrical and dosimetrical considerations compared to conventional IGRT [0.03%]
基于CBCT的膀胱在线自适应放射治疗-与常规IGRT比较的几何和剂量学考虑因素
Jann Fischer,Laura Anna Fischer,Jona Bensberg et al.
Jann Fischer et al.
Background: Bladder cancer radiotherapy presents unique challenges due to the dynamic anatomy of the bladder and the surrounding organs. Conventional image-guided radiotherapy (IGRT) relies on fixed treatment margins and ...
A stacking ensemble framework integrating radiomics and deep learning for prognostic prediction in head and neck cancer [0.03%]
一种集成影像组学和深度学习的头颈部肿瘤预后预测算法框架
Bingzhen Wang,Jinghua Liu,Xiaolei Zhang et al.
Bingzhen Wang et al.
Background: Radiomics models frequently face challenges related to reproducibility and robustness. To address these issues, we propose a multimodal, multi-model fusion framework utilizing stacking ensemble learning for pr...
Elevated MS4A12 expression is indicative of resistance to concurrent chemoradiotherapy and inferior survival in patients with rectal cancer [0.03%]
MS4A12高表达提示直肠癌患者同步放化疗耐药及预后不良
Chih-I Chen,Yi-Kai Kao,Po-Wen Yang et al.
Chih-I Chen et al.
Introduction: In individuals presenting with locally advanced rectal cancer, the therapeutic strategy of neoadjuvant concurrent chemoradiotherapy (CCRT) aims to enhance tumor downstaging; however, only a subset of patient...
From standardized to individualized margins for online adaptive tumor dose escalation in rectal cancer [0.03%]
从标准化到个体化的边缘区剂量提升用于直肠癌的自适应在线肿瘤剂量递增治疗研究
C M Kensen,Lisa Wiersema,Anja Betgen et al.
C M Kensen et al.
Purpose: To determine the impact of tumor characteristics such as tumor volume, circumference and location in the rectum on intrafraction motion during dose-escalated MRI-guided radiotherapy of rectal cancer and to explor...
Proton therapy for adult type IDH-mutated glioma: Proglio-1, a multicenter retrospective study [0.03%]
成人型IDH突变胶质瘤的质子治疗：Proglio-1多中心回顾性研究
Nicolas Goliot,Emmanuel Jouglar,Julian Jacob et al.
Nicolas Goliot et al.
Background: Gliomas with isocitrate dehydrogenase (IDH) mutation affect young adults with a long-life expectancy. While radiotherapy is effective, studies have shown its detrimental effects on cognition and quality of lif...
Multicenter Study
Radiation oncology (London, England). 2025 Aug 5;20(1):124. DOI:10.1186/s13014-025-02702-y 2025
A prospective outcomes and cost-effective analysis of surgery compared to stereotactic body radiation therapy for stage I non-small cell lung cancer [0.03%]
立体定向放疗与I期非小细胞肺癌手术的疗效及成本效益分析
Andrew Kennedy,Shanna A Arnold Egloff,Casey Martin et al.
Andrew Kennedy et al.
Background: To evaluate long-term outcomes, treatment costs, and quality of life associated with curative treatment of newly diagnosed stage I non-small cell lung cancer (NSCLC), by comparing surgery to stereotactic body ...
Comparative Study
Radiation oncology (London, England). 2025 Aug 5;20(1):123. DOI:10.1186/s13014-025-02699-4 2025
Early prediction of proton therapy dose distributions and DVHs for hepatocellular carcinoma using contour-based CNN models from diagnostic CT and MRI [0.03%]
基于轮廓的CNN模型在质子治疗肝细胞癌剂量分布和DVHs早期预测中的应用研究
Toshiya Rachi,Taku Tochinai
Toshiya Rachi
Background: Proton therapy is commonly used for treating hepatocellular carcinoma (HCC); however, its feasibility can be challenging to assess in large tumors or those adjacent to critical organs at risk (OARs), which are...
Early prediction of histopathological response of locally advanced rectal cancer after 1 week of preoperative radiochemotherapy using 18FDG PET-CT imaging: a prospective clinical validation study [0.03%]
使用18FDG PET-CT成像对接受术前放化疗1周的局部晚期直肠癌患者进行组织病理学反应早期预测：一项前瞻性临床验证研究
Yulia Kundel,Zoya Cohen,Noa Gordon et al.
Yulia Kundel et al.
Background: Neoadjuvant (preoperative) radiochemotherapy (nRCT) is a standard of care in locally advanced rectal cancer (LARC). Several studies have shown that the decline in 18FDG uptake after 2 weeks of nRCT compared wi...
Management of critically located brain metastases in patients with precluded survival using customised double-dose prescription-based, adaptive accelerated staged radiosurgery: a long-term retrospective analysis [0.03%]
基于自适应加速分阶段放射外科手术的定制双倍剂量方案在预期生存期有限且伴有关键部位脑转移瘤患者中的应用：长期回顾性分析
G Sinclair,H Martin,C M Allison et al.
G Sinclair et al.
Background: Patients with brain metastases face a poor prognosis when deemed not to be suitable for onco-surgical intervention. This feasibility study analyses the outcome of adaptive radiosurgery applied in customised se...