Comparative metabolomic analysis of human lung slices (hu-PCLS) exposed to either standard or FLASH protons: a pilot study [0.03%]
人肺组织片(hu-PCLS)暴露于标准质子或FLASH质子的代谢组学分析:一项初步研究
Anastasia Velalopoulou,Tytus D Mak,Annabella Deziel et al.
Anastasia Velalopoulou et al.
Background: Recent advances in radiation biology and preclinical research have identified that high doses of radiation at ultra-high dose rate can lead to sparing of normal tissue, while maintaining tumor control. This ha...
Surrogating tumour cell density in head and neck cancer: [18F]FDG PET- versus ADC (MRI)-based approaches [0.03%]
头颈癌中以[18F]FDG-PET和ADC(磁共振成像)为基础的肿瘤细胞密度替代法的比较
Athanasios Kafkaletos,Ilias Sachpazidis,Michael Mix et al.
Athanasios Kafkaletos et al.
Objective: In this study we examined the correlation between standardized uptake value (SUV) of [18F]fluorodeoxyglucose (FDG) and apparent diffusion coefficient (ADC) within the gross tumor volume (GTV) of patients with h...
Comparative Study
Radiation oncology (London, England). 2025 Sep 1;20(1):137. DOI:10.1186/s13014-025-02716-6 2025
Technical aspects of SBRT for therapy-refractory ventricular tachycardia: a systematic review for radiation oncologists [0.03%]
射波刀治疗难治性室速的技术要点——针对放射肿瘤科医师的系统综述
Alicia Greiner,Lukas Grajewski,Maximilian Römer et al.
Alicia Greiner et al.
Background: Ventricular tachycardia (VT) is a potentially life-threatening arrhythmia, that can lead to sudden cardiac death. While conventional treatments include antiarrhythmic drugs, catheter ablation, and ICD implanta...
Nasopharyngeal cancer adaptive radiotherapy with CBCT-derived synthetic CT: deep learning-based auto-segmentation precision and dose calculation consistency on a C-Arm linac [0.03%]
基于CBCT的鼻咽癌自适应放疗:深度学习自动勾画精度及C形臂直线加速器剂量计算一致性研究
Weijie Lei,Lixiang Han,Zhenmei Cao et al.
Weijie Lei et al.
Background: To evaluate the precision of automated segmentation facilitated by deep learning (DL) and dose calculation in adaptive radiotherapy (ART) for nasopharyngeal cancer (NPC), leveraging synthetic CT (sCT) images d...
Comprehensive one-day management of prostate cancer patients: PRO-FAST single-fraction ablative, urethral-sparing, HDR-like, robotic SBRT [0.03%]
前列腺癌患者的全面单日管理:PRO-FAST单一疗程消融、尿道保护、HDR类似、机器人SBRT疗法
Andrei Fodor,Laura Giannini,Miriam Torrisi et al.
Andrei Fodor et al.
Background: Radiotherapy (RT) is a standard curative treatment for prostate cancer (PCa) and there is growing evidence of the high efficacy of moderate and ultra-hypofractionated RT. Reducing treatment duration to one wee...
Use of PULSAR (personalized ultra-fractionated stereotactic adaptive radiotherapy) as consolidation with immune checkpoint inhibition in the treatment of pediatric metastatic melanoma [0.03%]
帕博利珠单抗联合个性化超分割立体定向自适应放疗治疗儿童转移性黑色素瘤的研究
Kyra L McCarty,Tanya Watt,Tu D Dan et al.
Kyra L McCarty et al.
We present a case of extensive and bulky pediatric metastatic melanoma originating in the head and neck which markedly responded to combination therapy with anti-programmed cell death (PD-1) inhibition and consolidative personalized ultra-f...
Tumor irradiation induced immunogenic response: the impact of DNA damage induction and misrepair [0.03%]
肿瘤放射免疫原性反应:DNA损伤诱导与修复不当的影响
Qi Liu,Xiaoran Shi,Nilupaier Tayier et al.
Qi Liu et al.
Focal tumor irradiation, a cornerstone of cancer therapy, has been increasingly recognized for its capacity to provoke systemic immunogenic responses that extend beyond localized tumor control. Recent advances highlight DNA damage, especial...
Criteria-calibration approaches to deep learning-based cervical cancer radiation treatment auto-planning [0.03%]
基于深度学习的宫颈癌放射治疗自动计划的准则校准方法
Yongguang Liang,Jingru Yang,Shuoyang Wei et al.
Yongguang Liang et al.
Background: Knowledge-Based Planning (KBP) pipelines, which integrate machine learning-based models to predict dose distribution, have gained popularity in clinical radiation therapy. However, for patients with specific r...
CT-based auto-segmentation of multiple target volumes for all-in-one radiotherapy in rectal cancer patients [0.03%]
基于CT的自动分割多目标区在直肠癌患者全身放疗中的应用
Xuemin Li,Luqi Wang,Mengying Yang et al.
Xuemin Li et al.
Background: This study aimed to evaluate the clinical feasibility and performance of CT-based auto-segmentation models integrated into an All-in-One radiotherapy workflow for rectal cancer. ...
Integrating peritumor and tumor CT radiomics features in predicting local control after SBRT in patients with pulmonary oligometastases [0.03%]
结合立体定向放疗后肺寡转移瘤患者瘤内和瘤周CT影像组学特征预测局部控制概率
Yao Lu,Yiqi Wang,Yuxi Ding et al.
Yao Lu et al.
Purpose: Local control prediction for patients with pulmonary oligometastases underwent stereotactic body radiotherapy (SBRT) is crucial for optimizing therapeutic strategies. This study aims to develop and validate a pre...