Ming Xia,Yu Chen,Hongzhi Shen et al.
Ming Xia et al.
Precise control and a clear understanding of the interfaces between 2D and 3D perovskites remain limited by structural disorder, interfacial defects and poorly defined growth pathways. Here we report a strategy for coherent van der Waals cr...
Ultrafast, reconfigurable all-optical beam steering and spatial light modulation [0.03%]
超快可重构全光学光束转向和空间光调制
Claudio U Hail,Lior Michaeli,Harry A Atwater
Claudio U Hail
Achieving spatiotemporal control of light at subwavelength and subcycle scales is an important milestone in the development of new photonic materials for signal processing, pulse shaping and ultrafast imaging. Spatiotemporal light modulatio...
A high-energy hydrogen radical initiates efficient electrosynthesis of urea from CO2 and N2 [0.03%]
高能量氢自由基高效电合成尿素研究
Hengan Wang,Jiankang Liu,Ran Duan et al.
Hengan Wang et al.
The electrochemical co-reduction of CO2 and N2 to urea presents a sustainable alternative to conventional synthesis but faces substantial challenges. Here we design a catalyst by anchoring the ionic liquid (IL) 1-ethyl-2,3-dimethylimidazoli...
Lin Lin,Haohui Li,Qi Zhou et al.
Lin Lin et al.
Intracavitary drug instillation is a crucial therapeutic strategy for treating bladder cancer. However, current methods are limited in efficacy due to insufficient tumour targeting and drug penetration across tissue barriers in pathophysiol...
Amplifying tumour antigen presentations from intratumourally entrapped dendritic cells [0.03%]
肿瘤内困获的树突状细胞放大肿瘤抗原呈递
Jingjing Zhang,Jiaxin Du,Kuoran Xing et al.
Jingjing Zhang et al.
Antigen presentation within solid tumours presents a significant clinical challenge for systemic immune activation. Although radiotherapy or chemotherapy can generate tumour antigens by destroying tumour cells, the insufficient number and i...
Precision-engineered STING agonist nanoparticles enable coordinated mucosal-systemic immunity for durable pan-β-coronavirus protection [0.03%]
精密工程STING激动剂纳米颗粒可协调黏膜全身免疫，实现持久的泛β冠状病毒防护
Zezhong Liu,Jie Zhou,Ruiyu Gao et al.
Zezhong Liu et al.
A major barrier in mucosal vaccine development is achieving localized immunity without systemic toxicity. Here we engineered NanoCF501, a nanoparticulate STING agonist formulated with a 2-ethyl-2-oxazoline polymer. As an adjuvant, NanoCF501...
Optical multistability in a compact microcavity enabled by near-exceptional coupling [0.03%]
近异常耦合实现的微腔光学多稳态现象
Zhen Liu,Xuefan Yin,Andrey Bogdanov et al.
Zhen Liu et al.
Multistability-the presence of multiple stable states under identical conditions-is a hallmark of nonlinear complexity, and in optics, a key enabler for multilevel optical memory. Yet, realizing optical multistability in a compact footprint...
High-resolution nanopore peptide sensing, profiling and sequence assembly [0.03%]
高分辨率纳米孔肽段感应、分析及序列组装技术
Kefan Wang,Xingwang An,Xinmeng Gao et al.
Kefan Wang et al.
Nanopores have been explored as a potential platform for protein analysis following the success of nanopore nucleic acid sequencing. However, protein sequencing remains technically challenging and has not yet been established for proteomics...
Nano-enabled spatially selective protein degradation modulates lactate metabolism to potentiate antitumor immunity in liver cancer [0.03%]
纳米技术实现的空间选择性蛋白降解可调节肝癌中的乳酸代谢以增强抗肿瘤免疫反应
Jinhong Du,Shu Han,Rui Song et al.
Jinhong Du et al.
Dysregulated cancer metabolism, driven in part by excessive lactate export through monocarboxylate transporters 1 (MCT1) and 4 (MCT4), generates an acidic tumour microenvironment that suppresses antitumour immunity and diminishes therapeuti...