Avigail Baruch Leshem,Dor Gaash,Ayala Lampel
Avigail Baruch Leshem
Designed biomolecular condensates are emerging condensed-phase assemblies, initially conceived to mimic cellular biomolecular condensates for use in biology-inspired applications such as delivery and storage of biomolecules. In recent years...
An ultrasmall core-shell silica nanoparticle improves antitumour immunity and survival by remodelling suppressive melanoma microenvironments [0.03%]
超小型核壳结构二氧化硅纳米颗粒通过重塑抑制性黑色素瘤微环境提高抗肿瘤免疫并改善生存率
Gabriel De Leon,Li Zhang,Nabil A Siddiqui et al.
Gabriel De Leon et al.
Despite the considerable success of clinically approved immune-based therapies for treating advanced melanoma, a significant fraction of patients are not responsive owing to mechanisms engaged by the tumour to evade the immune system. Here ...
Viral glycoprotein-mimicking peptide-functionalized micelles promote drug delivery to diseased chondrocytes for osteoarthritis alleviation [0.03%]
模拟病毒糖蛋白的肽修饰的米勒粒促进药物向骨关节炎病灶软骨细胞传递以缓解病情
Xiao Chen,Dongyang Zhou,Jian Wang et al.
Xiao Chen et al.
Osteoarthritis (OA) affects a large population worldwide, causing chronic pain, functional decline, and increased personal and societal medical costs. A major challenge in developing disease-modifying OA drugs (DMOADs) is the inefficient de...
Navigating the future of assisted reproductive technology with micro-robotics, nanobiosensors and artificial intelligence [0.03%]
辅助生殖技术的未来展望：微机器人、纳米生物传感器和人工智能的作用
Friedrich Striggow,Pallavi Jha,Ripla Arora et al.
Friedrich Striggow et al.
Fundamental optical phenomena of strongly anisotropic polaritons at the nanoscale [0.03%]
强各向异性的纳米极化激元的基本光学现象
Yixi Zhou,Zhiwei Guo,Aitana Tarazaga Martín-Luengo et al.
Yixi Zhou et al.
Polaritons are hybrid quasiparticles consisting of photons and electric (or magnetic) dipole-carrying excitations. Their observation has advanced our understanding of light-matter interactions and led to the manipulation of energy flows at ...
A biohybrid chiral hydrogel enhances preclinical postoperative glioblastoma therapy by multi-pronged inhibition of tumour stemness [0.03%]
手性生物水凝胶通过多途径抑制肿瘤干细胞特性增强术后的临床胶质母细胞瘤治疗效果
Tingting Cui,Sixue Chen,Siqin Liu et al.
Tingting Cui et al.
Glioblastoma stem cells (GSCs), which exhibit resistance to multiple treatments, are a prominent driver of postoperative glioblastoma (GBM) relapse. Reducing the GSC population holds promise in GBM therapy but remains challenging due to the...
Florian Dirnberger,Sophia Terres,Zakhar A Iakovlev et al.
Florian Dirnberger et al.
Optical quasiparticles called magnetic excitons recently emerged in magnetic van der Waals materials. Akin to the highly effective strategies developed for electrons, the strong interactions of these excitons with the spin degree of freedom...
Machine perception liquid biopsy identifies brain tumours via systemic immune and tumour microenvironment signature [0.03%]
机器感知液态活检通过全身免疫和肿瘤微环境标志物识别脑肿瘤
Dana Goerzen,Mijin Kim,Chanel Schroff et al.
Dana Goerzen et al.
The detection and identification of intracranial tumours is limited by the lack of accurate biomarkers and requires invasive biopsy procedures. We investigated a machine perception liquid biopsy approach to detect and identify intracranial ...
Elizaveta Semenova,Alexander Huck
Elizaveta Semenova
Michael Torrice
Michael Torrice