The role of exogenous risk factors in amyotrophic lateral sclerosis in Wakayama, Japan [0.03%]
日本和歌山县遗传性运动神经元病的外源性危险因素及其作用
Tameko Kihira,Seizi Kanno,Hideto Miwa et al.
Tameko Kihira et al.
The incidence of ALS in Wakayama Prefecture has been markedly higher than that elsewhere in the world. Recently, however, the incidence has gradually decreased, especially in men, and the age at onset has shifted to the elderly, indicating ...
Association of polymorphisms in vascular endothelial growth factor gene with the age of onset of amyotrophic lateral sclerosis [0.03%]
血管内皮生长因子基因多态性与肌萎缩侧索硬化发病年龄的关联研究
Dafang Chen,Li Shen,Liping Wang et al.
Dafang Chen et al.
This study investigated the association between polymorphisms in vascular endothelial growth factor (VEGF) gene (-1558C-T, -1190A-G and -1154A-G) and age at onset of amyotrophic lateral sclerosis (ALS). Between July 2000 and June 2004 we co...
Role of zinc in ALS [0.03%]
锌在ALS中的作用
Andrew P Smith,Nancy M Lee
Andrew P Smith
The causes of amyotrophic lateral sclerosis (ALS) are poorly understood. A small proportion, about 2%, is associated with a mutation in the superoxide dismutase (SOD1) gene, and mice expressing this mutant gene exhibit a progressive, ALS-li...
Stacy A Rudnicki,Robert L Archer,Bishoy T Labib
Stacy A Rudnicki
Giancarlo Logroscino,Stefano Zoccolella
Giancarlo Logroscino
Clinical highlights. 17th International Symposium on ALS/MND Yokohama, Japan, November 30, 2006 through December 2, 2006 [0.03%]
国际ALS/MND研讨会临床亮点日本横滨2006年11月30日到12月2日
Hisoshi Mitsumoto
Hisoshi Mitsumoto
Nikos Karandreas,Marianna Papadopoulou,Panagiotis Kokotis et al.
Nikos Karandreas et al.
The pathogenesis of sporadic amyotrophic lateral sclerosis (ALS) remains unknown. Neurophysiological studies provide evidence of hyperexcitability of the motor cortex or of impairment of inhibitory intrahemispheric modulation of the cortico...
A comparison of maximal inspiratory pressure and forced vital capacity as potential criteria for initiating non-invasive ventilation in amyotrophic lateral sclerosis [0.03%]
比较最大吸气压和用力肺活量作为在肌萎缩侧索硬化中启动无创通气的潜在标准的效果
Michelle Mendoza,Deborah F Gelinas,Dan H Moore et al.
Michelle Mendoza et al.
Using a retrospective analysis of 161 patients with amyotrophic lateral sclerosis (ALS) from the Western ALS study group (WALS) database, the sensitivity of maximal inspiratory pressure (MIP)< -60 cm H(2)O and forced vital capacity (FVC)< 5...
Sleep characteristics of amyotrophic lateral sclerosis in patients with preserved diaphragmatic function [0.03%]
膈肌功能保存的肌萎缩侧索硬化患者的睡眠特征
António Atalaia,Mamede De Carvalho,Teresinha Evangelista et al.
António Atalaia et al.
There are a number of sleep studies in amyotrophic lateral sclerosis (ALS), in general including a heterogeneous population of patients. We aimed to study sleep in a population of selected ALS patients by investigating nocturnal polysomnogr...