A role for functional classification in the early identification of prognostic factors in ALS [0.03%]
功能分类在ALS预后因素早期识别中的作用
Amy C Rauchway,Kitti Kaiboriboon,Sachin K Bansal et al.
Amy C Rauchway et al.
The aim of this study was to determine if the interval between onset of symptoms to initial electrodiagnostic studies indicates disease progression in amyotrophic lateral sclerosis (ALS). Fifty consecutive patients referred to our neurophys...
Good practice in the management of amyotrophic lateral sclerosis: clinical guidelines. An evidence-based review with good practice points. EALSC Working Group [0.03%]
肌萎缩侧索硬化症管理的规范做法：基于循证的临床指南及其关键实践点
Peter Munch Andersen,Gian Domenico Borasio,Reinhard Dengler et al.
Peter Munch Andersen et al.
The evidence base for diagnosis and management of ALS is still weak, and curative therapy is lacking. Nonetheless, early diagnosis and symptomatic therapy can profoundly influence care and quality of life of the patient and relatives, and m...
Dimitris Karacostas,Dimitris Parissis,Barbara Michailidou et al.
Dimitris Karacostas et al.
Inappropriate sexual behaviour in a case of ALS and FTD: successful treatment with sertraline [0.03%]
ALS和FTD病例中的不当性行为：西酞普兰治疗成功
Johanna M H Anneser,Ralf J Jox,Gian Domenico Borasio
Johanna M H Anneser
In a subset of patients, ALS is associated with frontotemporal dysfunction (ALS-FTD). Clinically, ALS-FTD may present with a variable spectrum of cognitive and behavioural deficits. We report a 53-year-old ALS-FTD patient developing inappro...
Early use of non-invasive ventilation prolongs survival in subjects with ALS [0.03%]
早期无创通气延长肌萎缩侧索硬化患者的生存时间
Noah Lechtzin,Yanille Scott,Anne M Busse et al.
Noah Lechtzin et al.
Non-invasive positive pressure ventilation (NPPV) can improve survival in ALS patients with advanced respiratory impairment, but it is not known if it is beneficial earlier in the disease course. A retrospective cohort study of patients wit...
Susana Pinto,Anabela Pinto,António Atalaia et al.
Susana Pinto et al.
Respiratory dysfunction is a critical problem in amyotrophic lateral sclerosis (ALS). We report a patient with ALS who had respiratory apraxia. A 74-year-old female presented with progressive dysarthria and dysphagia. Clinical signs and evi...
Three soccer playing friends with simultaneous amyotrophic lateral sclerosis [0.03%]
三位患肌萎缩侧索硬化症的足球运动员朋友
Paul Wicks,Jeban Ganesalingham,Christine Collin et al.
Paul Wicks et al.
Amyotrophic lateral sclerosis is a neurodegenerative disease of largely unknown cause, predominantly affecting upper and lower motor neurons. A recent study in Italy suggested an increased incidence of ALS among professional Italian soccer ...
Quantitative assessment of motor fatigue: normative values and comparison with prior-polio patients [0.03%]
肌张力疲劳的定量评估及其与 polio 康复者的比较研究
Dara Meldrum,Eibhlis Cahalane,Ronan Conroy et al.
Dara Meldrum et al.
Motor fatigue is a common complaint of polio survivors and has a negative impact on activities of daily living. The aim of this study was to establish a normative database for hand grip strength and fatigue and to investigate differences be...
Perceptions of quality of life in people with ALS: effects of coping and health care [0.03%]
渐冻症患者的生活质量感知：应对能力和医护效果的影响
Geraldine Foley,Paul O&#x;Mahony,Orla Hardiman
Geraldine Foley
Few qualitative studies have explored the 'meaning' of life experiences for persons with ALS. We aimed to identify the meaning of QoL in five selected individuals, and to consider how their experience of health care affected perceived well-...
Effect of non-steroidal anti-inflammatory medications on the risk of amyotrophic lateral sclerosis [0.03%]
非甾体抗炎药物与肌萎缩侧索硬化发病风险之间的关系
Rita A Popat,Caroline M Tanner,Stephen K van den Eeden et al.
Rita A Popat et al.
Inflammatory processes may be involved in the pathogenesis of amyotrophic lateral sclerosis (ALS). We examined the association of non-steroidal anti-inflammatory drugs (NSAIDs) with the risk of ALS in case-control study of incident cases (n...