Mycobacterium tuberculosis fluorescent and bioluminescent imaging technologies: addressing the issue of sensitivity [0.03%]
结核分枝杆菌荧光和生物发光活体成像技术——如何提高灵敏度问题？
Amanda C Zangirolami,Aaron B Benjamin,Hatice Ceylan Koydemir et al.
Amanda C Zangirolami et al.
Introduction: Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is a common cause of death in humans worldwide. The slow growth rate of Mtb (~20 hours) makes progress in research slow and diagnosis difficult....
Humidification insights in Mechanical ventilation and respiratory support. A narrative review [0.03%]
机械通气和呼吸支持中的加湿见解。叙述性综述
Kunal Deokar,Gustavo A Plotnikow,Sanjay Singhal et al.
Kunal Deokar et al.
Introduction: Adequate airway humidification is important in respiratory care, significantly affecting patient comfort, airway function, and clinical outcomes. Adequate humidification helps prevent airway dryness, mucosal...
Inhaled nitric oxide in therapy of pediatric and neonatal acute respiratory distress syndrome: the good, the bad and the ugly [0.03%]
一氧化氮吸入治疗儿童和新生儿急性呼吸窘迫综合征的利弊优缺点分析
Qi He,Shuyue Liu,Wenwen Tang et al.
Qi He et al.
Introduction: Pediatric and neonatal acute respiratory distress syndrome (PARDS/NARDS) cause significant mortality or long-term morbidity in childhood. The optimal management remains elusive, making a review of therapies ...
Treatment options for children with pulmonary arterial hypertension associated with congenital heart disease [0.03%]
儿童先天性心脏病相关肺动脉高压的治疗选择
Julie Wacker,Raphael Joye,Maurice Beghetti
Julie Wacker
Introduction: Pulmonary hypertension associated with congenital heart disease (PAH-CHD) represents one of the leading causes of pediatric pulmonary hypertension. Within this entity, patients can be classified into distinc...
Is dual bronchodilation a cost-effective alternative to ICS/LABA in COPD? A Colombian healthcare system evaluation [0.03%]
双支气管扩张疗法是否是慢性阻塞性肺疾病患者中使用吸入型皮质类固醇/长效β2受体激动剂的具成本效益替代治疗方案？一项哥伦比亚医疗体系评估研究
Jefferson Antonio Buendía,Diana Guerrero Patiño
Jefferson Antonio Buendía
Background: Chronic obstructive pulmonary disease (COPD) is a major public health challenge in Colombia, particularly among older adults. Although ICS/LABA combinations like fluticasone/salmeterol (FSC) are widely used, d...
Safety and efficacy of mepolizumab in eosinophilic chronic obstructive pulmonary disease: a systematic review and meta-analysis [0.03%]
美普兹单抗治疗嗜酸细胞性慢性阻塞性肺病的安全性和有效性：系统综述和meta分析
Jorge Sinclair De Frías,Agostina Velo,Lorenzo Olivero et al.
Jorge Sinclair De Frías et al.
Introduction: Up to 40% of patients with COPD have an eosinophilic phenotype, which increases the risk of acute exacerbations. Mepolizumab, an anti - IL-5 monoclonal antibody, has shown mixed results. We conducted a syste...
Spatially resolved airway niches: mapping epithelial-immune microenvironments in asthma [0.03%]
哮喘患者气道微生态的细胞空间图谱
Molham Sakkal,Anan S Jarab,Ahmad Z Al Meslamani
Molham Sakkal
Introduction: Spatially resolved omics has reconceptualized the bronchial wall as a mosaic of epithelial - immune microenvironments whose local molecular circuits drive asthma heterogeneity and medication responsiveness. ...
Indwelling pleural catheters for the treatment of malignant pleural effusions; where are we now? [0.03%]
植入式胸膜导管治疗恶性胸腔积液：现状如何？
William E Thinnes,Jennifer D Duke,James Katsis et al.
William E Thinnes et al.
Introduction: Malignant pleural effusions (MPE) affect many patients with advanced malignant disease and lead to significant symptomatic burden. Management is primarily focused on controlling symptoms. IPCs are considered...
Ahmad Z Al Meslamani
Ahmad Z Al Meslamani
Introduction: Type-2-high (T2-high) asthma remains the most prevalent phenotype of this chronic airway disease. Accumulating evidence implicates the gut - lung microbiome axis as the principal mechanism underlying T2-immu...
Insights into sinonasal disease in patients with primary ciliary dyskinesia [0.03%]
原发性纤毛运动障碍患者的鼻窦疾病的特征分析
Ela Erdem Eralp,Bulent Karadag
Ela Erdem Eralp
Introduction: Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterized by impaired motile ciliary function, resulting in defective mucociliary clearance and chronic sinopulmonary disease. Although lower a...