Recognizing and managing excessive respiratory drive and effort: an expert narrative review [0.03%]
过度呼吸驱动和呼吸努力的识别与处理：专家叙述性综述
Giorgia Pacchiarini,Francesco Monteleone,Francesco Zarantonello et al.
Giorgia Pacchiarini et al.
Introduction: Patient self-inflicted lung injury (P-SILI) has been proposed as a contributor to lung damage during spontaneous breathing or partially assisted ventilation. P-SILI usually arises from excessive inspiratory ...
Glucocorticoid-induced muscle weakness in ECOPD: a perspective on mechanisms and emerging pharmacological interventions [0.03%]
糖皮质激素诱发的慢性阻塞性肺病急性加重期肌肉力量下降：机制及药物干预手段展望
Sandra J van Krimpen,Sami O Simons,Annemie M W J Schols et al.
Sandra J van Krimpen et al.
Introduction: Muscle weakness represents a significant clinical problem in chronic obstructive pulmonary disease (COPD). During exacerbations of COPD (ECOPD), inflammation, oxidative stress, malnutrition, disuse, hypoxia,...
Recent updates on thymic stromal lymphopoietin as a therapeutic target for asthma [0.03%]
哮喘治疗靶点胸腺基质淋巴细胞生成素研究进展近况
Ravneet K Hansi,Christiane E Whetstone,Maral Ranjbar et al.
Ravneet K Hansi et al.
Introduction: Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine shown to bridge innate and adaptive immunity, and orchestrates airway inflammation across both type 2 (T2)-high and T2-low asthma. Emergi...
Haemophilus influenzae in the airways: canary in the coal mine or driver of disease? [0.03%]
流感嗜血杆菌与呼吸道疾病的关系：是发病的驱动因素还是警示指标？
Jodie Ackland,Lauren Bowron,Michael Joseph Cox et al.
Jodie Ackland et al.
Introduction: Overgrowth and colonization by non-typeable Haemophilus influenzae (NTHi) is a common feature of increasing disease severity, treatment resistance and increased susceptibility to disease exacerbations across...
Effectiveness of rehabilitation interventions in adults with moderate-to-severe asthma: an extended systematic review [0.03%]
针对成人中重度哮喘患者的康复干预效果的扩展系统评价
Rossana Cuscito,Laura Cricenti,Ilaria Ruotolo et al.
Rossana Cuscito et al.
Introduction: Physical deconditioning is common in adults with moderate-to-severe asthma, negatively affecting respiratory function, disease control and quality of life (QoL). Pulmonary rehabilitation may improve both fun...
Dual protection in IPF: antifibrotic therapy and reduced lung cancer incidence- a systematic review and meta-analysis [0.03%]
特发性肺纤维化中双重保护：抗纤维化治疗与肺癌发病率降低- 系统评价和meta分析
Narat Srivali,Federica De Giacomi
Narat Srivali
Background: Idiopathic pulmonary fibrosis (IPF) significantly increases lung cancer risk, with cumulative incidence exceeding 50% at 10 years. We evaluated whether antifibrotic therapies provide cancer-protective effects ...
Consensus-based standardization of procedural steps for indwelling pleural catheter placement: a modified Delphi study [0.03%]
一种带入式胸膜导管置入术操作步骤共识标准化的改良德尔菲研究
Juan C Lara,Chan Y Pu,Fayez Kheir et al.
Juan C Lara et al.
Background: Indwelling pleural catheters (IPCs) are commonly used for managing recurrent pleural effusion, yet standardized techniques for their placement are lacking. This study aimed to establish a consensus on IPC plac...
Mucus plugs in large airways are associated with adverse hospitalization outcomes in acute exacerbation of chronic obstructive pulmonary disease [0.03%]
慢性阻塞性肺疾病急性加重期大气道内粘液栓与不良住院结局相关性研究
Dianmei Zhou,Lijuan Gao,Lian Liu et al.
Dianmei Zhou et al.
Background: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) impose a substantial health-economic burden. Although mucociliary dysfunction is a key pathophysiological feature linked to adverse outcome...
A review of the safety of antibody therapy in severe eosinophilic asthma [0.03%]
严重嗜酸性粒细胞性哮喘抗体治疗的安全性评述
Maria Gabriella Matera,Vito De Novellis,Paola Rogliani et al.
Maria Gabriella Matera et al.
Introduction: Severe eosinophilic asthma (SEA) is characterized by persistent type 2 airway inflammation and frequent exacerbations despite maximal conventional therapy. The advent of biologics targeting interleukin-5, it...