Early versus Late starting of Direct Oral Anticoagulants after breakthrough ischemic stroke: A Target Trial Analysis from the ASPERA-R Study [0.03%]
ASPERA-R研究中的目标试验分析：早期与晚期开始使用突破性缺血性卒中后的直接口服抗凝药
Lucio D&#x;Anna,Matteo Foschi,Francesca Gabriele et al.
Lucio D&#x;Anna et al.
Background and purpose: Randomized trials support early initiation of direct oral anticoagulants (DOACs) after atrial fibrillation (AF)-related ischemic stroke, but patients with breakthrough ischemic stroke occurring des...
HERMES-24 Score for Outcome Prediction in Large Vessel Occlusion Stroke: Real-World Data from the Austrian Stroke Network [0.03%]
HERMES-24评分在大血管闭塞卒中结局预测中的应用价值：奥地利卒中网络的真实世界数据
Thomas Gattringer,Alexander Pichler,Dominika Miksova et al.
Thomas Gattringer et al.
Background: The HERMES-24 score has recently been proposed to estimate 90-day outcome in patients with anterior circulation large vessel occlusion (LVO) stroke. ...
Adjunctive Intra-Arterial Alteplase After Near-Complete or Complete Reperfusion in Acute Ischemic Stroke: A Post Hoc Analysis of the PEARL Trial [0.03%]
在急性缺血性卒中近似完全或完全再灌注后的动脉内alteplase辅助治疗：来自PEARL试验的事后分析
Mingyi Bao,Chunnuan Chen,Haoyang Sun et al.
Mingyi Bao et al.
Background: The benefit of adjunctive intra-arterial alteplase treatment following near-complete to complete reperfusion (expanded Thrombolysis in Cerebral Infarction [eTICI] scale of 2c to 3) by mechanical thrombectomy f...
Small vessel disease burden and response to induced hypertension therapy in small vessel occlusion stroke with early neurological deterioration [0.03%]
小血管疾病负担与小血管闭塞性卒中早期神经功能恶化患者血压诱导治疗反应的关系研究
Wookjin Yang,Keon-Yeup Kim,Jeong Kyu Lee et al.
Wookjin Yang et al.
Background: Induced hypertension therapy (iHT) is used to rescue early neurological deterioration (END) in small vessel occlusion (SVO) stroke. However, underlying perforator dysfunction reflected by small vessel disease ...
The role of inflammation in cerebral small vessel disease and vascular cognitive impairment, and therapeutic implications [0.03%]
炎症在脑小血管病及血管性认知障碍中的作用及其治疗意义
Robin Brown,Stuart M Allan,Hugh Stephen Markus
Robin Brown
Increasing evidence suggests that inflammation occurs in cerebral small vessel disease (SVD). Inflammation has been hypothesised to play a role in disease pathogenesis, and also in progression to vascular cognitive impairment and dementia (...
Two distinct patterns of progression of sporadic cerebral small vessel disease [0.03%]
两种不同形式的散发性脑小血管病的发展模式
Yutong Chen,Hui Hong,Daniel Tozer et al.
Yutong Chen et al.
Background: Sporadic cerebral small vessel disease (cSVD) is the most common cause of vascular dementia. cSVD features a wide range of neuroimaging markers including white matter hyperintensity (WMH), lacunes, perivascula...
Large Artery occlusion Treated in Extended Time with Mechanical Thrombectomy (LATE-MT): protocol for a multicenter randomized clinical trial [0.03%]
延长取栓时间治疗大动脉闭塞的多中心随机对照临床研究（LATE-MT）方案
Hongjian Shen,Pengfei Yang,Lili Song et al.
Hongjian Shen et al.
Background: High-quality randomized controlled trials (RCTs) have extended the endovascular therapy (EVT) time window to 24 hours post-stroke onset in selected patients with acute ischemic stroke (AIS). Recent retrospecti...
Safety and efficacy of early antiplatelet therapy after intravenous thrombolysis for acute ischemic stroke; A comprehensive meta-analysis with trial sequential analysis [0.03%]
急性缺血性卒中溶栓后早期抗血小板治疗的安全性和有效性：全面的meta分析及试验序列分析
Hamdy A Makhlouf,Ahmed Harb,Moaz Elsayed Abouelmagd et al.
Hamdy A Makhlouf et al.
Background: Early antiplatelet therapy after intravenous thrombolysis (IVT) in acute ischemic stroke (AIS) patients may prevent re-occlusion and early neurological deterioration, but it could increase hemorrhagic transfor...
Risk of growth of tiny (≤3 mm) unruptured intracranial aneurysms: a retrospective cohort study of 228 tiny aneurysms [0.03%]
228枚小型(≤3毫米)未破裂颅内动脉瘤生长风险的队列研究
Jolijn van de Putte,Mervyn D I Vergouwen,Maarten Kamphuis et al.
Jolijn van de Putte et al.
Background: Tiny unruptured intracranial aneurysms (UIAs), defined as ≤3 mm, are increasingly detected due to advancements in imaging. However, the optimal management approach remains uncertain. Studies have questioned t...
Early Hematoma Absorption After Intracerebral Hemorrhage: Clinical Characteristics, Neurological Evolution, and Outcomes [0.03%]
早期脑内血肿吸收后的临床特征、神经功能演变和结局
Xiao Hu,Zijie Wang,Min Liu et al.
Xiao Hu et al.
Background: Early hematoma absorption (HA) has been insufficiently investigated in patients with intracerebral hemorrhage (ICH). This study aimed to determine the prevalence of HA and to evaluate its association with neur...