Renal biopsy is necessary for the diagnosis of HIV-associated renal diseases [0.03%]
肾活检对HIV相关肾脏病的诊断是必要的
Scott D Cohen,Paul L Kimmel
Scott D Cohen
Sharon Silbiger
Sharon Silbiger
This Practice Point commentary discusses a study by Ahmed et al. that evaluated the effects of hormone replacement therapy (conjugated estrogen alone, progestin alone or a combination of progestin and conjugated estrogen) on renal function ...
Predicting the ideal serum creatinine level following kidney transplantation [0.03%]
预测肾移植后的理想血清肌酐水平
Greg A Knoll
Greg A Knoll
This Practice Point commentary reviews a study by Sberro et al. that evaluated formulae to predict the lowest measured serum creatinine concentration in kidney transplant recipients following surgery. The objective of the study was to ascer...
Lisa Nanovic,Bruce Kaplan
Lisa Nanovic
Although renal transplantation confers a survival advantage over maintenance dialysis in patients with end-stage renal disease, many factors can attenuate this survival advantage over the long term. Among the most important negative influen...
Fluid balance and acute kidney injury: the missing link for predicting adverse outcomes? [0.03%]
液体平衡与急性肾损伤：预测不良结局的缺失环节？
Ravindra L Mehta
Ravindra L Mehta
This Practice Point commentary discusses the findings from the secondary analysis of a large systematic cohort study of critically ill patients that evaluated the influence of fluid overload on outcomes from acute kidney injury (AKI). Payen...
Women with a history of preeclampsia should be monitored for the onset and progression of chronic kidney disease [0.03%]
有子痫前期病史的妇女应监测慢性肾脏疾病的发生和进展
Takayuki Hamano
Takayuki Hamano
This Practice Point commentary discusses a recent paper in which Vikse et al. demonstrated that history of preeclampsia is a marker for an increased risk of end-stage renal disease (ESRD). Among women with preeclampsia, giving birth to a lo...
Interpreting observational studies of disordered mineral metabolism and mortality in patients on hemodialysis [0.03%]
透析患者的矿紊代谢异常与死亡率的观察研究及其解读
David M Spiegel
David M Spiegel
This Practice Point commentary discusses the findings and limitations of a cohort study reported by Wald and colleagues of mineral metabolism in patients on hemodialysis. The investigators' observational analysis utilized data from the 1,84...
Does increased removal of high-molecular-weight toxins improve the survival of hemodialysis patients? [0.03%]
清除高分子量毒素的增加能否改善血液透析患者的生存率？
Richard A Ward
Richard A Ward
This commentary discusses a small multicenter, prospective clinical trial in which patients with end-stage renal disease were randomized to treatment with online high-flux hemofiltration or low-flux hemodialysis. Over a 3-year follow-up per...
Re-examining RAS-blocking treatment regimens for abrogating progression of chronic kidney disease [0.03%]
重新审视RAS阻断治疗方案以阻止慢性肾脏病进展
Murray Epstein
Murray Epstein
This commentary discusses the findings and profound clinical implications of a prespecified analysis of renal outcomes performed by Mann et al. in the large ONTARGET study. This study assessed the effects of the angiotensin-converting-enzym...
Calcimimetics or vitamin D analogs for suppressing parathyroid hormone in end-stage renal disease: time for a paradigm shift? [0.03%]
氯化钙或维生素D类似物通过抑制PTH来治疗终末期肾病：是时候转变观念了吗？
James B Wetmore,L Darryl Quarles
James B Wetmore
Considerable advances have been made in the understanding of the pathogenesis and treatment of secondary hyperparathyroidism (SHPT) in chronic kidney disease (CKD). These include the discovery that the calcium-sensing receptor has an import...