The role of cerebellar-cortical connectivity in modulating attentional abilities: insight from football athletes [0.03%]
小脑-皮层连接在调节注意力方面的作用：来自足球运动员的启示
Jian Wang,Siyu Gao,Junfu Tian et al.
Jian Wang et al.
Neuroplasticity, a phenomenon present throughout the lifespan, is thought to be influenced by physical training. However, the relationship between neuroplastic differences and attentional abilities remains unclear. This study explored the d...
Neonatal maternal separation causes depressive-like behavior and potentiates memory impairment induced by amyloid-β oligomers in adult mice [0.03%]
新生期母体分离导致的抑郁行为和由淀粉样寡聚体引发的记忆损伤在成年小鼠中的强化效应
Patrick R Suman,Grasielle C Kincheski,Rudimar L Frozza et al.
Patrick R Suman et al.
Background: Alzheimer's disease (AD) is characterized by memory decline and mood alterations. A growing body of evidence implicates stress and other social determinants of health as potential contributors to the progressi...
Improving effects of melatonin on memory and synaptic potentiation in a mouse model of Alzheimer's-like disease: the involvement of glutamate homeostasis and mGluRs receptors [0.03%]
褪黑激素对类似阿尔茨海默病小鼠模型的记忆和突触长时程增强作用的改善效应：谷氨酸稳态和mGluRs受体的作用
Narjes Khatoun Shabani Sadr,Fatemeh Bakhtiarzadeh,Koorosh Shahpasand et al.
Narjes Khatoun Shabani Sadr et al.
Background: Alzheimer's disease (AD) is characterized by progressive cognitive decline and synaptic dysfunction, largely driven by amyloid plaques and neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau. Th...
Dopamine D1 receptor agonist alleviates post-weaning isolation-induced neuroinflammation and depression-like behaviors in female mice [0.03%]
多巴胺D1受体激动剂减轻断乳后隔离引起的雌鼠神经炎症和类抑郁行为
Zi-Wei Zhao,Yun-Chen Wang,Pei-Chun Chen et al.
Zi-Wei Zhao et al.
Background: Major depressive disorder is a significant global cause of disability, particularly among adolescents. The dopamine system and nearby neuroinflammation, crucial for regulating mood and processing rewards, are ...
Investigating the role of the brain-derived neurotrophic factor Val66Met polymorphism in repetitive mild traumatic brain injury outcomes in rats [0.03%]
脑源性神经营养因子Val66Met基因多态性在轻度创伤性脑损伤中作用的研究
Lauren P Giesler,William T O&#x;Brien,Jesse Bain et al.
Lauren P Giesler et al.
Background: Mild traumatic brain injury (mTBI) poses a significant public health concern, particularly regarding repetitive injury, with outcomes ranging from acute neurobehavioral deficits to long-term impairments. While...
Effects of TrkB-related induced metaplasticity within the BLA on anxiety, extinction learning, and plasticity in BLA-modulated brain regions [0.03%]
与TrkB相关的BLA内源性代谢可塑性变化对焦虑、消退学习以及BLA调节脑区的可塑性的影响
Joyeeta Dutta Hazra,Kuldeep Shrivastava,Lisa-Sophie Wüstner et al.
Joyeeta Dutta Hazra et al.
Background: Neuronal plasticity within the basolateral amygdala (BLA) is fundamental for fear learning. Metaplasticity, the regulation of plasticity states, has emerged as a key mechanism mediating the subsequent impact o...
Sex differences in reward-based operant conditioning performance and neurotransmitter changes following chronic sleep restriction stress in rats [0.03%]
慢性睡眠限制应激大鼠奖赏式操作性条件反射表现及神经递质变化的性别差异研究
Yiwen Zhang,Fang Chen,Mubiao Yu et al.
Yiwen Zhang et al.
Background: Sleep deprivation significantly impairs cognitive function, which disrupts daily life. However, sex differences in these impairments are not well understood, as most preclinical studies primarily use male anim...
Fecal microbiota transplantation attenuates Alzheimer's disease symptoms in APP/PS1 transgenic mice via inhibition of the TLR4-MyD88-NF-κB signaling pathway-mediated inflammation [0.03%]
粪便微生物移植通过抑制 toll 样受体 4-myeloid differentiation primary response 88-nuclear factor-κb 信号通路介导的炎症减轻 app/ps1 转基因小鼠阿尔茨海默病症状
Xiang Li,Qingyong Ding,Xinxin Wan et al.
Xiang Li et al.
Alzheimer's disease (AD) is a prevalent and progressive neurodegenerative disorder that is the leading cause of dementia. The underlying mechanisms of AD have not yet been completely explored. Neuroinflammation, an inflammatory response med...
Host genetics maps to behaviour and brain structure in developmental mice [0.03%]
小鼠发育过程中宿主基因组学与行为及脑结构相关性研究
Sarah Asbury,Jonathan K Y Lai,Kelly C Rilett et al.
Sarah Asbury et al.
Gene-environment interactions in the postnatal period have a long-term impact on neurodevelopment. To effectively assess neurodevelopment in the mouse, we developed a behavioural pipeline that incorporates several validated behavioural test...
Can rewards enhance creativity? Exploring the effects of real and hypothetical rewards on creative problem solving and neural mechanisms [0.03%]
奖励能增强创造力吗？真实和假设性奖励对创造性问题解决及神经机制的影响研究
Can Cui,Yuan Yuan,Yingjie Jiang
Can Cui
Reward cues have long been considered to enhance creative performance; however, little is known about whether rewards can affect creative problem solving by manipulating states of flexibility and persistence. This study sought to elucidate ...