Lack of association between COMT gene and deficit/nondeficit schizophrenia [0.03%]
COMT基因与精神分裂症缺陷/非缺陷亚型无关
Ikwunga Wonodi,Braxton D Mitchell,O Colin Stine et al.
Ikwunga Wonodi et al.
Background: The dopamine dysregulation hypothesis of schizophrenia posits that positive, negative and cognitive symptoms correlate with cortical/subcortical imbalances in dopaminergic transmission. A functional polymorphi...
The alpha-2A adrenoceptor agonist guanfacine improves sustained attention and reduces overactivity and impulsiveness in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD) [0.03%]
选择性α-2A肾上腺素受体激动剂胍法辛改善注意缺陷多动障碍动物模型的持续注意力并减少过动和冲动行为
Terje Sagvolden
Terje Sagvolden
Background: ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as the main clinic...
Altered pattern of brain dopamine synthesis in male adolescents with attention deficit hyperactivity disorder [0.03%]
注意缺陷多动障碍男青少年脑内多巴胺合成的改变规律研究
Hans Forssberg,Elisabeth Fernell,Susanna Waters et al.
Hans Forssberg et al.
Background: Limited data from positron emission tomography (PET) studies of subjects with attention-deficit/hyperactivity disorder (ADHD) indicate alterations in brain dopamine neurotransmission. However, these studies ha...
Association study of the vesicular monoamine transporter 1 (VMAT1) gene with schizophrenia in a Japanese population [0.03%]
关于-vesicular单胺转运蛋白1（VMAT1）基因与日本人群精神分裂症的相关性研究
Misty Richards,Yoshimi Iijima,Hitomi Kondo et al.
Misty Richards et al.
Background: Vesicular monoamine transporters (VMATs) mediate accumulation of monoamines such as serotonin, dopamine, adrenaline, and noradrenaline from the cytoplasm into storage organelles. The VMAT1 (alternatively solut...
Simultaneity in the millisecond range as a requirement for effective shape recognition [0.03%]
百毫秒级的同时性是有效形状识别的必要条件
Ernest Greene
Ernest Greene
Neurons of the visual system are capable of firing with millisecond precision, and synchrony of firing may provide a mechanism for "binding" stimulus elements in the image for purposes of recognition. While the neurophysiology is suggestive...
Haloperidol treatment induces tissue- and sex-specific changes in DNA methylation: a control study using rats [0.03%]
卤operidol治疗诱导组织和性别特异性的DNA甲基化变化：使用大鼠进行的对照研究
Morihiro Shimabukuro,Yoshihiro Jinno,Chiaki Fuke et al.
Morihiro Shimabukuro et al.
Background: We previously found that there is a subtle difference in the global methylation state of blood leukocyte DNA between male subjects with and without schizophrenia. The aim of the current study was to determine ...
Claudia K Friedrich,Carsten Eulitz,Aditi Lahiri
Claudia K Friedrich
Background: If all available acoustic phonetic information of words is used during lexical access and consequently stored in the mental lexicon, then all pseudowords that deviate in a single acoustic feature from a word s...
Individual differences in decision making: Drive and Reward Responsiveness affect strategic bargaining in economic games [0.03%]
个体差异对决策的影响：动机与奖励反应性影响经济游戏中的战略议价
Anouk Scheres,Alan G Sanfey
Anouk Scheres
Background: In the growing body of literature on economic decision making, the main focus has typically been on explaining aggregate behavior, with little interest in individual differences despite considerable between-su...
Atypically diffuse functional connectivity between caudate nuclei and cerebral cortex in autism [0.03%]
自闭症患者壳核与大脑皮层之间的功能连接的异常扩散性
Katherine C Turner,Leonard Frost,David Linsenbardt et al.
Katherine C Turner et al.
Background: Autism is a neurodevelopmental disorder affecting sociocommunicative behavior, but also sensorimotor skill learning, oculomotor control, and executive functioning. Some of these impairments may be related to a...
Fine motor skills in South African children with symptoms of ADHD: influence of subtype, gender, age, and hand dominance [0.03%]
南非注意缺陷多动障碍患儿的精细运动技能：类型、性别、年龄和利手性的影响
Anneke Meyer,Terje Sagvolden
Anneke Meyer
Background: Motor problems, often characterised as clumsiness or poor motor coordination, have been associated with ADHD in addition to the main symptom groups of inattention, impulsiveness, and overactivity. The problems...