Cognition in anxious children with attention deficit hyperactivity disorder: a comparison with clinical and normal children [0.03%]
注意缺陷多动障碍焦虑儿童的认知研究——与临床及正常儿童的比较
Katharina Manassis,Rosemary Tannock,Arlene Young et al.
Katharina Manassis et al.
Background: Cognition in children with anxiety disorders (ANX) and comorbid Attention Deficit Disorder (ADHD) has received little attention, potentially impacting clinical and academic interventions in this highly disable...
An association study of DRD2 and COMT polymorphisms with novelty seeking and harm avoidance scores, in two independent samples of depressed patients [0.03%]
关于DRD2和COMT基因多态性与两组独立的抑郁症样本中求新性和回避伤害性的关联研究
Katrina J Light,Peter R Joyce,Suzanne E Luty et al.
Katrina J Light et al.
Background: It was recently reported that an interaction of the dopamine D2 receptor (DRD2) and catechol-O-methyltransferase (COMT) influences the behavioural approach system--as measured using Carver and White's Behaviou...
Examining impulsivity as an endophenotype using a behavioral approach: a DRD2 TaqI A and DRD4 48-bp VNTR association study [0.03%]
采用行为方法研究冲动性作为潜在表型:多巴胺D2受体Taq I A和多巴胺D4受体48- bpVNTR相关联研究
Dan T A Eisenberg,James Mackillop,Meera Modi et al.
Dan T A Eisenberg et al.
Background: Research on the genetic basis for impulsivity has revealed an array of ambiguous findings. This may be a result of limitations to self-report assessments of impulsivity. Behavioral measures that assess more na...
Electrophysiological evidence for notation independence in numerical processing [0.03%]
数值处理中符号无关性的电生理学证据
Melissa E Libertus,Marty G Woldorff,Elizabeth M Brannon
Melissa E Libertus
Background: A dominant view in numerical cognition is that numerical comparisons operate on a notation independent representation (Dehaene, 1992). Although previous human neurophysiological studies using scalp-recorded ev...
Working memory deficits in adults with ADHD: is there evidence for subtype differences? [0.03%]
注意缺陷多动障碍成人工作记忆损伤的亚型差异性研究
Julie B Schweitzer,Russell B Hanford,Deborah R Medoff
Julie B Schweitzer
Background: Working memory performance is important for maintaining functioning in cognitive, academic and social activities. Previous research suggests there are prevalent working memory deficits in children with attenti...
Lack of association between COMT gene and deficit/nondeficit schizophrenia [0.03%]
COMT基因与精神分裂症缺陷/非缺陷亚型无关
Ikwunga Wonodi,Braxton D Mitchell,O Colin Stine et al.
Ikwunga Wonodi et al.
Background: The dopamine dysregulation hypothesis of schizophrenia posits that positive, negative and cognitive symptoms correlate with cortical/subcortical imbalances in dopaminergic transmission. A functional polymorphi...
The alpha-2A adrenoceptor agonist guanfacine improves sustained attention and reduces overactivity and impulsiveness in an animal model of Attention-Deficit/Hyperactivity Disorder (ADHD) [0.03%]
选择性α-2A肾上腺素受体激动剂胍法辛改善注意缺陷多动障碍动物模型的持续注意力并减少过动和冲动行为
Terje Sagvolden
Terje Sagvolden
Background: ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as the main clinic...
Altered pattern of brain dopamine synthesis in male adolescents with attention deficit hyperactivity disorder [0.03%]
注意缺陷多动障碍男青少年脑内多巴胺合成的改变规律研究
Hans Forssberg,Elisabeth Fernell,Susanna Waters et al.
Hans Forssberg et al.
Background: Limited data from positron emission tomography (PET) studies of subjects with attention-deficit/hyperactivity disorder (ADHD) indicate alterations in brain dopamine neurotransmission. However, these studies ha...
Association study of the vesicular monoamine transporter 1 (VMAT1) gene with schizophrenia in a Japanese population [0.03%]
关于-vesicular单胺转运蛋白1(VMAT1)基因与日本人群精神分裂症的相关性研究
Misty Richards,Yoshimi Iijima,Hitomi Kondo et al.
Misty Richards et al.
Background: Vesicular monoamine transporters (VMATs) mediate accumulation of monoamines such as serotonin, dopamine, adrenaline, and noradrenaline from the cytoplasm into storage organelles. The VMAT1 (alternatively solut...
Simultaneity in the millisecond range as a requirement for effective shape recognition [0.03%]
百毫秒级的同时性是有效形状识别的必要条件
Ernest Greene
Ernest Greene
Neurons of the visual system are capable of firing with millisecond precision, and synchrony of firing may provide a mechanism for "binding" stimulus elements in the image for purposes of recognition. While the neurophysiology is suggestive...