Correlation of prefrontal-based resting state functional connectivity with the degree of cognitive impairment in Alzheimer's disease: a functional near-infrared spectroscopy study [0.03%]
基于前额叶静息态功能连接与阿尔茨海默病认知障碍程度关联的功能近红外光谱成像研究
Ming Chen,Wenbo Zhang,Mengyu Yan et al.
Ming Chen et al.
Background: This study aims to investigate the differences in neural network connectivity within the prefrontal cortex (PFC) among elderly individuals with normal cognition (NC), mild cognitive impairment (MCI), and Alzhe...
Brain network efficiency during social interaction is associated with real-world social network size [0.03%]
大脑社交互动网络效率与现实生活中社交圈规模相关
Mengfei Han,Xin Liu,Yongcong Shao et al.
Mengfei Han et al.
Social ties critically influence individual health and well-being, raising important questions about why some individuals occupy advantageous social network positions. While social cognition is known to play a key role, it remains unclear w...
Regulation of glial markers expression in the rat basolateral amygdala and hippocampus during morphine aversive memory retrieval and its extinction [0.03%]
吗啡条件性厌恶记忆的提取及其消退过程中基底外侧杏仁核和海马胶质标志物表达的调节规律研究
Aurelio Franco-García,Victoria Gómez-Murcia,Cristina Núñez
Aurelio Franco-García
Background: Opioid use disorder is driven by neurobehavioral adaptations where environmental cues trigger relapse. Consequently, extinction therapy (ET) aims to modify drug-associated memories but has limited long-term ef...
Space and time in words: exploring neural overlap and specificity [0.03%]
从语言角度探究时空概念的神经基础：Overlap和Specificity模型预测的检验
Francesca Conca,Giulia Mattavelli,Claudia Gianelli et al.
Francesca Conca et al.
Background: A common magnitude system-consistently involving the right intraparietal sulcus (IPS)-has been proposed to support the representation of space, time and numerosity. While shared mechanisms are acknowledged, do...
Wenqi Chen,Yan Hao
Wenqi Chen
Cognitive functions are critical to everyday life, and enhancing cognitive abilities has significant implications for both individual development and societal advancement. However, there remains no consensus on whether cognitive capacities ...
Ru-Xia Xu,Shi-Han Liao,Nan Wang et al.
Ru-Xia Xu et al.
This study aimed to investigate the sex-dependent behavioral effects of tamoxifen, commonly used to induce Cre recombination in transgenic systems, across three developmental stages (adult, adolescent, and neonatal) and two CreERT2 mouse li...
Quercetin nanoemulsion ameliorates tremor and neuroinflammatory dysregulation: behavioral and molecular insights in a mouse model of essential tremor [0.03%]
檞皮素纳米乳剂改善震颤和神经炎症失调：必要性震颤小鼠模型的行为学和分子机制研究视角
Zeynab Pirmoradi,Monavareh Soti,Kristi A Kohlmeier et al.
Zeynab Pirmoradi et al.
Background: Essential tremor (ET) is a common movement disorder characterized by persistent limb tremors. Currently, no effective treatment for ET exists. Natural plant-derived compounds, like the flavonoid, quercetin may...
Overexpression of Hspa1b in the mouse hippocampus may be associated with major depressive disorder [0.03%]
小鼠海马区Hspa1b过表达可能与抑郁症有关
Xiaofeng Zhao,Yanan Shang,Wenli Zhu et al.
Xiaofeng Zhao et al.
Heat Shock Protein Family A Member 1B (Hspa1b) is an RNA binding protein that regulates transcriptional and post transcriptional processes. Previous studies have suggested its protective role in stress adaptation and post injury depression,...
Sex-dimorphic oxytocin regulation of CA1-dependent spatial memory and synaptic plasticity in juvenile rats [0.03%]
催产素调节雄性大鼠海马CA1区依赖的空间记忆和突触可塑性
Evleen Shehadeh,Nisha Rajan Narattil,Milly Kritman et al.
Evleen Shehadeh et al.
Research into memory mechanisms has predominantly centered on adult male rodents, often overlooking the influences of sex and developmental stage. Memory processes vary significantly between juveniles and adults, with sex acting as a critic...
Aging-related changes in cognitive flexibility: fMRI meta-analysis [0.03%]
认知灵活性的老化改变：基于fMRI的meta分析研究
Zhanna Chuikova,Andrei Faber,Andrei Filatov et al.
Zhanna Chuikova et al.
Cognitive flexibility-the ability to adaptively shift between different mental processes-is essential for human functioning. This meta-analysis examines age-related changes in neural correlates of cognitive flexibility using two common asse...