Enhancement of neurogenesis and cognition through intranasal co-delivery of galanin receptor 2 (GALR2) and neuropeptide Y receptor 1 (NPY1R) agonists: a potential pharmacological strategy for cognitive dysfunctions [0.03%]
通过鼻内共递送胰高血糖素样肽-1受体和神经肽Y受体激动剂增强神经发生和认知：一种潜在的认知障碍药物策略
Raquel Sánchez-Varo,Alexander López-Salas,Rasiel Beltran-Casanueva et al.
Raquel Sánchez-Varo et al.
Background: Spatial memory deficits and reduced neuronal survival contribute to cognitive decline seen in the aging process. Current treatments are limited, emphasizing the need for innovative therapeutic strategies. This...
An automatic system for recognizing fly courtship patterns via an image processing method [0.03%]
通过图像处理方法识别苍蝇求偶行为的自动系统
Ching-Hsin Chen,Yu-Chiao Lin,Sheng-Hao Wang et al.
Ching-Hsin Chen et al.
Fruit fly courtship behaviors composed of a series of actions have always been an important model for behavioral research. While most related studies have focused only on total courtship behaviors, specific courtship elements have often bee...
Changes in effective connectivity during the visual-motor integration tasks: a preliminary f-NIRS study [0.03%]
视觉运动整合任务过程中有效连接性的变化：一项初步的f-NIRS研究
Wenchen Wang,Haimei Li,Yufeng Wang et al.
Wenchen Wang et al.
Background: Visual-motor integration (VMI) is an essential skill in daily life. The present study aimed to use functional near-infrared spectroscopy (fNIRS) technology to explore the effective connectivity (EC) changes am...
The role of melatonin deficiency induced by pinealectomy on motor activity and anxiety responses in young adult, middle-aged and old rats [0.03%]
松果体切除术引起的褪黑激素缺乏对年轻成人、中年和老年大鼠运动活动及焦虑反应的作用
Jana Tchekalarova,Desislava Krushovlieva,Petj Ivanova et al.
Jana Tchekalarova et al.
Background: Aging affects anxiety levels in rats while the pineal gland, via its hormone melatonin, could modulate their inherited life "clock." The present study aimed to explore the impact of plasma melatonin deficiency...
Structural connectome alterations between individuals with autism and neurotypical controls using feature representation learning [0.03%]
自闭症个体与典型神经个体之间结构连接组改变的研究使用特征表示学习方法
Yurim Jang,Hyoungshin Choi,Seulki Yoo et al.
Yurim Jang et al.
Autism spectrum disorder is one of the most common neurodevelopmental conditions associated with sensory and social communication impairments. Previous neuroimaging studies reported that atypical nodal- or network-level functional brain org...
Behavioral characterization of early nicotine withdrawal in the mouse: a potential model of acute dependence [0.03%]
小鼠早期尼古丁戒断的行为特征：急性依赖的潜在模型
Baeksun Kim,Heh-In Im
Baeksun Kim
Background: Clinical and preclinical research have demonstrated that short-term exposure to nicotine during the initial experimentation stage can lead to early manifestation of withdrawal-like signs, indicating the state ...
Divesh Thaploo,Akshita Joshi,Eren Yilmaz et al.
Divesh Thaploo et al.
Objective: Parosmia is a qualitative olfactory dysfunction presenting as "distorted odor perception" in presence of an odor source. Aim of this study was to use resting state functional connectivity to gain more informati...
Inhibition of astroglial hemichannels ameliorates infrasonic noise induced short-term learning and memory impairment [0.03%]
抑制星形胶质细胞半通道改善次声噪声所致短期学习和记忆损伤
Wei Zhang,Jue Yin,Bei-Yao Gao et al.
Wei Zhang et al.
As a kind of environmental noise, infrasonic noise has negative effects on various human organs. To date, research has shown that infrasound impairs cognitive function, especially the ability for learning and memory. Previously, we demonstr...
Interaction between childhood trauma experience and TPH2 rs7305115 gene polymorphism in brain gray matter volume [0.03%]
童年创伤经历与TPH2基因多态性在大脑灰质体积相互作用的研究
Wei Li,Qian Li,Peng Zhang et al.
Wei Li et al.
Background: Childhood trauma is one of the most extensively studied and well-supported environmental risk factors for the development of mental health problems. The human tryptophan hydroxylase 2 (TPH2) gene is one of the...
Reactivity of the ventromedial prefrontal cortex, but not the amygdala, to negative emotion faces predicts greed personality trait [0.03%]
伏隔核而不是杏仁核对负面情绪面孔的反应预测贪婪的人格特征
Kun Deng,Weipeng Jin,Keying Jiang et al.
Kun Deng et al.
This study explored whether amygdala reactivity predicted the greed personality trait (GPT) using both task-based and resting-state functional connectivity analyses (ntotal = 452). In Cohort 1 (n = 83), task-based functional magnetic resona...