Federal procurement of unlicensed medicines in Brazil; findings and implications [0.03%]
巴西政府采购未授权药物；发现与影响分析
Cristiane Roberta Dos Santos Teodoro,Rosângela Caetano,Brian Godman et al.
Cristiane Roberta Dos Santos Teodoro et al.
Background: There are safety concerns with using unlicensed medicines across countries including Brazil. Consequently this needs to be evaluated and concerns address if pertinent. ...
The value of open access and a patient centric approach to oral oncolytic utilization in the treatment of Chronic Myelogenous Leukemia: A U.S. perspective [0.03%]
从美国视角看口服肿瘤溶解药在慢性髓性白血病治疗中采用开放访问和以患者为中心的方法的价值
Lopamudra Das,Matthew Gitlin,Lisa R Siegartel et al.
Lopamudra Das et al.
Since the introduction of tyrosine kinase inhibitors (TKIs), the treatment of patients with chronic myelogenous leukemia (CML) has resulted in significant improvement in patient survival but at a higher pharmaceutical cost to payers. The re...
Losing a foot versus losing a dollar; a systematic review of cost studies in diabetic foot complications [0.03%]
糖尿病足并 发症的成本研究系统综述：失去一只脚与失去一美元？
Ioannis Petrakis,Ilias J Kyriopoulos,Alexandros Ginis et al.
Ioannis Petrakis et al.
Diabetes mellitus is a chronic disease with high prevalence worldwide and a range of serious related complications. Amongst them, diabetic foot is one of the most disabling, posing a substantial health and economic burden on patients and he...
Using lower cost statins improves outcomes for normal cholesterol non-diabetic patients [0.03%]
使用低成本的他汀类药物可改善正常胆固醇非糖尿病患者的效果
Ronen Arbel,Dan Greenberg
Ronen Arbel
Background: The American College of Cardiology recommends considering initiation of cholesterol-lowering therapy in normal cholesterol adults aged 45-70, who are either diabetic or have a 10 year atherosclerotic cardiovas...
Economic analysis of the phase III MENSA study evaluating mepolizumab for severe asthma with eosinophilic phenotype [0.03%]
关于MENSA三期研究的经济分析：美柏利珠单抗用于治疗重度嗜酸粒细胞性哮喘患者
Anirban Basu,Anand Dalal,Giorgio Walter Canonica et al.
Anirban Basu et al.
Background: Severe eosinophilic asthma patients are at risk of exacerbations, which are associated with substantial costs. Mepolizumab lowers eosinophil levels and reduces exacerbation risk in severe eosinophilic asthma. ...
Treatment plan comparison in acute and chronic respiratory tract diseases: an observational study of doxophylline vs. theophylline [0.03%]
急性及慢性呼吸道疾病治疗方案比较：多索茶碱与氨茶碱临床观察研究
F S Mennini,P Sciattella,A Marcellusi et al.
F S Mennini et al.
Background: The main objective of this article is to estimate the global cost related to the use of the two drugs (associated drugs, specialist visits, hospital admissions, plasma drug monitoring). ...
The treatment patterns of castration-resistant prostate cancer in Japan, including symptomatic skeletal events and associated treatment and healthcare resource use [0.03%]
日本去势抵抗性前列腺癌治疗模式及其相关症状性骨骼事件和医疗资源使用情况
Hiroji Uemura,Marco DiBonaventura,Ed Wang et al.
Hiroji Uemura et al.
Background: Real-world treatment patterns of bone metastatic castration-resistant prostate cancer (mCRPC) in Japan were examined, focusing on treatment patterns and resource use differences attributed to symptomatic skele...
Health-state utility estimates for health technology assessment: a review of the manufacturers' submissions to the French National Authority for Health [0.03%]
法国国家卫生管理局的制造商关于健康技术评估的健康状态功效估计综述
Françoise F Hamers,Salah Ghabri,Catherine Le Gales
Françoise F Hamers
Background: Our aim was to review the selection and methods used for deriving health state utility (HSU) estimates included in the cost-utility analyses (CUA) submitted by manufacturers to the National Authority for Healt...
The insights of health and welfare professionals on hurdles that impede economic evaluations of welfare interventions [0.03%]
卫生与福利专业人士关于阻碍福利干预经济效益评估的难题的见解
J Schepers,J Plaete,I De Bourdeaudhuij et al.
J Schepers et al.
Background: Four hurdles associated with economic evaluations in welfare interventions were identified and discussed in a previous published literature review. These hurdles include (i) 'Ignoring the impact of condition-s...
Usha Sambamoorthi,Drishti Shah,Xiaohui Zhao
Usha Sambamoorthi
Arthritis and depression are two of the top disabling conditions. When arthritis and depression exist in the same individual, they can interact with each other negatively and pose a significant healthcare burden on the patients, their famil...