Mirna Bobinac,Ana Bobinac,Ismar Velić et al.
Mirna Bobinac et al.
Background: Minimal important difference (MID) thresholds distinguish noticeable from meaningful health gains, yet reimbursement decisions often fund high-cost therapies with marginal benefit. Clarifying meaningful patien...
Development of a resource use measurement (RUM) instrument to estimate the economic burden of suicide in India [0.03%]
在印度开发资源使用测量(RUM)工具以估算自杀的经济负担
Nikhil Jain,Isha Lohumi,Vanessa Ravel et al.
Nikhil Jain et al.
Background: Suicide related events lead to the mobilization of a diverse array of resources affecting multiple sectors across society. These resources include healthcare service utilization, out-of-pocket expenditures, pr...
A brave New world: the rise of agentic AI in rapid cycle RWE Analytics [0.03%]
勇于新世界：快速循环真实世界证据分析中代理式人工智能的崛起
Won Chan Lee,Brent Mankin,David Hood
Won Chan Lee
Introduction: Real-world evidence (RWE) has become a critical asset across drug discovery and market access, with regulators accepting evidence from real-world data (RWD) to supplement negotiations. With increasing demand...
From model validation to policy resilience: stress testing healthcare systems with AI and cross-sectorial methodology [0.03%]
从模型验证到政策复原力：使用AI和跨行业方法测试卫生系统压力测试
Freija van Lent,Lieke Maas
Freija van Lent
Estimating respiratory syncytial virus health utility values for older adults and their caregivers in the Japanese population: a time trade-off study [0.03%]
日本老年人和护理人员呼吸道合胞病毒健康效用值估算：时间交易法研究
Regina Rendas-Baum,Jakob Bjorner,Victor Preckler et al.
Regina Rendas-Baum et al.
Background: Respiratory syncytial virus (RSV) is a common virus affecting the respiratory system in all ages. The study's objective was to obtain RSV-related health utility values for older adults and their caregivers fro...
Analyzing the direct medical cost of Schizophrenia in Hospital Pulau Pinang, Malaysia [0.03%]
马来西亚槟城医院精神分裂症的直接医疗费用分析
Fuad Fadhel Alotaibi,Abdulrahman A Alsuhibani,Ong Siew Chin et al.
Fuad Fadhel Alotaibi et al.
Background: Schizophrenia (SCZ) is a major public health concern that places a significant economic burden on healthcare systems. This study assessed the direct medical costs of SCZ and examined cost drivers at Hospital P...
The relationship between changes in prescription drug sales and changes in mortality and hospital utilization in Denmark, 2005-2019 [0.03%]
2005~2019年丹麦处方药销售变化与死亡率和住院率变化之间的关系
Frank R Lichtenberg
Frank R Lichtenberg
Background: The objective of this study is to investigate the relationship between changes in prescription drug sales and changes in mortality and hospital utilization in Denmark during the period 2005-2019. ...
Estimated cost-effectiveness of adjuvant nivolumab for resected stage IIB-IIC melanoma in the United States [0.03%]
美国IIB-II期黑色素瘤患者辅助纳武利尤单抗治疗的成本效益评估
Islam Eljilany,Vakaramoko Diaby
Islam Eljilany
Background: The CheckMate 76K trial analysis showed that the use of nivolumab as adjuvant therapy in the treatment of patients with resected stage IIB-IIC melanoma reduced recurrence-free survival (RFS). This study aimed ...
Cost and clinical analysis of community-acquired pneumonia within an antimicrobial stewardship-governed academic hospital in South Africa, and its implications [0.03%]
南非一家抗菌药物管理治理的学术医院中社区获得性肺炎的成本和临床分析及其意义
Katlego Bjang,Madimetje Kutume,Nthabiseng Mongoai et al.
Katlego Bjang et al.
Background: Pneumonia is a common respiratory infection treated with antibiotics. Patients needing antibiotics risk poor outcomes due to antimicrobial resistance (AMR). In LMIC, inappropriate prescribing is common due to ...
Antimicrobial resistance as an economic externality: optimal control, Pigouvian taxation, and governance implications [0.03%]
抗生素抗药性作为经济外部性：最优控制、庇古税和治理含义
Aritra Jana,Debnarayan Khatua,Santi M Mandal
Aritra Jana
Background: The rise of antimicrobial resistance (AMR) is a major concern worldwide, with serious implications for health and the economy. Global burden estimates, coupled with mortality projections for 2019, indicate tha...