De-escalating locoregional Radiation therapy in Breast cancer: balancing promises and prudence [0.03%]
乳腺癌中降低区域放射治疗剂量：权衡利弊
Gustavo Nader Marta,Orit Kaidar-Person,Icro Meattini et al.
Gustavo Nader Marta et al.
Introduction: The integration of primary systemic therapy (PST) into breast cancer management increasingly shapes locoregional treatment. Rising pathological complete response rates and improved survival have fueled inter...
Integrating artificial intelligence across the bladder cancer continuum: progress, promise, and pitfalls [0.03%]
人工智能在膀胱癌全程管理中的整合：进展、前景与挑战
Sri Saran Manivasagam,Jay D Raman,Alireza Aminsharifi
Sri Saran Manivasagam
Introduction: Bladder cancer is a prevalent and costly malignancy, with persistent challenges in early detection, accurate staging, and personalized treatment planning. Artificial intelligence (AI) has emerged as a transf...
Pediatric acute myeloid leukemia in Uruguay: clinical outcomes and diagnostic challenges in a National cohort (2008-2024) [0.03%]
乌拉圭儿童急性髓系白血病的临床结局和诊断挑战（2008-2024年全国队列数据）
Gabriel Dapueto,Inés Pereira,Lucía D&#x;Andrea et al.
Gabriel Dapueto et al.
Background: Outcomes for pediatric acute myeloid leukemia (AML) have improved substantially in high-income countries through advances in therapy, supportive care, and risk stratification. In Uruguay, results remain poorer...
Overcoming toxicity challenges in immune checkpoint inhibitor treatment of high-risk metastatic cancers [0.03%]
克服免疫检查点抑制剂治疗高危转移性癌症的毒性挑战
Rishitha Nalabothu,Douglas B Johnson
Rishitha Nalabothu
Introduction: Immune checkpoint inhibitors (ICI) have become a cornerstone of cancer treatment and induce durable responses in many patients with advanced cancer. However, they cause immune-related adverse events (irAEs) ...
Do genetic polymorphisms influence imatinib trough concentrations in patients with chronic myeloid leukemia? A systematic review and meta-analysis [0.03%]
基因多态性影响慢性髓性白血病患者伊马替尼谷浓度吗？系统评价和meta分析
Francisco Cezar Aquino de Moraes,Gustavo Tadeu Freitas Uchôa Matheus,Luis Henrique Rios Moreira Rego et al.
Francisco Cezar Aquino de Moraes et al.
Pretreatment hyperferritinaemia as an Independent prognostic Marker in metastatic solid tumours treated with immune checkpoint inhibitors [0.03%]
基线血清铁蛋白升高的转移性实体瘤患者接受免疫检查点抑制剂治疗的预后意义
Fatma Pinar Açar,Caner Acar,Haydar Çağatay Yüksel et al.
Fatma Pinar Açar et al.
Background: Hyperferritinaemia is common in cancer and may reflect tumor-associated macrophage activity and ferroptosis resistance, yet its prognostic value during immune checkpoint inhibitor (ICI) therapy is uncertain. ...
Impact of HPV vaccination after a diagnosis of cervical HSIL - a case-control study [0.03%]
人乳头瘤病毒疫苗接种对宫颈高度鳞状上皮内病变诊断的影响-一项病例对照研究
Pedro Vieira-Baptista,Joana Lima-Silva,Gonçalo Freitas et al.
Pedro Vieira-Baptista et al.
Background: This study aimed to evaluate the impact of HPV vaccination at the time of treatment of cervical intraepithelial neoplasia (CIN) 2+ on recurrence/persistence. ...
Genomic divergence between matched primary and metastatic tumors across cancer types: a pan-cancer analysis of 5,692 samples [0.03%]
跨越癌症类型匹配原发肿瘤和转移性肿瘤的基因组差异：对5,692个样本进行的泛癌分析
Yakup Ergun
Yakup Ergun
Background: Metastasis is the leading cause of cancer-related death and involves biological processes such as genomic instability and immune evasion. Although metastatic tumors generally retain major alterations present i...
The prognostic significance of lymph node metastases characteristics in papillary thyroid carcinoma: a scoping review [0.03%]
乳头状甲状腺癌淋巴结转移特征的预后意义：系统综述式的回顾性研究
Gurvir Singh Dhutt,Laura Ellis,Sam M Wiseman
Gurvir Singh Dhutt
Introduction: Despite neck lymph node metastases occurring commonly in cases of papillary thyroid carcinoma (PTC), there has remained controversy regarding the thresholds that should be used for lymph node characteristics...
Unveiling the power of PARP inhibitors: a meta-analysis on newly diagnosed advanced ovarian cancer maintenance therapy [0.03%]
PARP抑制剂新篇：初治晚期卵巢癌维持治疗的meta分析
Wanfang Zhang,Ni Zhang,Shaojie Li et al.
Wanfang Zhang et al.
Introduction: This meta-analysis sought to assess the efficacy and safety of poly (adenosine diphosphate-ribose) polymerase inhibitors (PARPi) as maintenance therapy for patients with newly diagnosed advanced ovarian canc...