Antibodies to human angiopoietin-like protein 3: a patent evaluation of WO2012174178 [0.03%]
人胎盘类血管生成素样蛋白3抗体:WO2012174178专利评估报告
Katsuyuki Nakajima,Junji Kobayashi
Katsuyuki Nakajima
The patent WO2012174178 claims the effect of a fully human antibody or antigen-binding fragment of a human antibody which specifically binds and neutralizes, inhibits, blocks, abrogates, reduces or interferes with the activity of human angi...
Novel oxytocin receptor agonists and antagonists: a patent review (2002 - 2013) [0.03%]
催产素受体激动剂与拮抗剂新药研究的专利回顾(2002-2013)
Yang Yang,Hao Li,Richard Ward et al.
Yang Yang et al.
Introduction: Oxytocin is a nine amino acid cyclic peptide hormone with a high degree of uterotonic activity. The oxytocin receptor (Oxtr) is most strongly expressed in the uterus and mammary gland, but can also be found ...
Osteoclast differentiation inhibitors: a patent review (2008 - 2012) [0.03%]
关于破骨细胞分化抑制剂的专利回顾(2008-2012)
Seong Hwan Kim,Seong-Hee Moon
Seong Hwan Kim
Introduction: Mononuclear macrophage/monocyte-lineage hematopoietic precursors differentiate into multinucleated osteoclasts. Abnormally increased numbers and/or overactivation of osteoclasts can lead to bone loss. Theref...
Novel FabH inhibitors: an updated article literature review (July 2012 to June 2013) [0.03%]
新型FabH抑制剂研究进展(2012年7月-2013年6月)
Heng Song,Gui-Zhen Ao,Huan-Qiu Li
Heng Song
Introduction: Fatty acid biosynthesis is essential for the bacterial viability and growth. In recent years, β-ketoacyl-acyl carrier protein synthase III (FabH) become an attractive new target, which catalyzes the first s...
Revocation of European patent for neural progenitors highlights patent challenges for inventions relating to human embryonic stem cells [0.03%]
欧洲神经干细胞专利撤销凸显人类胚胎干细胞发明面临的专利挑战
Barbara Rigby
Barbara Rigby
Cells derived from human embryonic stem cells have great therapeutic potential. Patents are key to allowing companies that develop methods of generating such cells to recuperate their investment. However, in Europe, inventions relating to t...
Paulina Kosikowska,Adam Lesner
Paulina Kosikowska
Introduction: Cathepsin G (CatG) is a neutral proteinase originating from human neutrophils. It displays a unique dual specificity (trypsin- and chymotrypsin-like); thus, its enzymatic activity is difficult to control. Ca...
Manasi Telang,Sivakami Dhulap,Anita Mandhare et al.
Manasi Telang et al.
Introduction: Mangiferin, a natural C-glucoside xanthone [2-C-β-D-glucopyranosyl-1, 3, 6, 7-tetrahydroxyxanthone], is abundantly present in young leaves and stem bark of the mango tree. The xanthonoid structure of mangif...
Tobias G Kapp,Florian Rechenmacher,Tariq R Sobahi et al.
Tobias G Kapp et al.
Introduction: Integrins are heterodimeric cell surface receptors, which enable adhesion, proliferation, and migration of cells by recognizing binding motifs in extracellular matrix (ECM) proteins. As transmembrane linkers...
John M Pezzuto,Tamara P Kondratyuk,Talysa Ogas
John M Pezzuto
Introduction: There is currently a wealth of information on the effects of resveratrol and its derivatives in therapeutic, cosmetic and nutraceutical patent applications. Structure-activity studies of the resveratrol scaf...
Indoleamine 2,3-dioxygenase inhibitors: a patent review (2008 - 2012) [0.03%]
色氨酸2,3-双氧酶抑制剂专利综述(2008-2012)
Eduard Dolušić,Raphaël Frédérick
Eduard Dolušić
Introduction: The inhibition of indoleamine 2,3-dioxygenase (IDO) has emerged as a key area in cancer immunotherapy in the past decade. Despite the large variety of potential inhibitors screened so far, the number of acti...