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期刊名:Expert opinion on therapeutic patents

缩写:EXPERT OPIN THER PAT

ISSN:1354-3776

e-ISSN:1744-7674

IF/分区:4.6/Q1

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共收录本刊相关文章索引1521
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Katsuyuki Nakajima,Junji Kobayashi Katsuyuki Nakajima
The patent WO2012174178 claims the effect of a fully human antibody or antigen-binding fragment of a human antibody which specifically binds and neutralizes, inhibits, blocks, abrogates, reduces or interferes with the activity of human angi...
Yang Yang,Hao Li,Richard Ward et al. Yang Yang et al.
Introduction: Oxytocin is a nine amino acid cyclic peptide hormone with a high degree of uterotonic activity. The oxytocin receptor (Oxtr) is most strongly expressed in the uterus and mammary gland, but can also be found ...
Seong Hwan Kim,Seong-Hee Moon Seong Hwan Kim
Introduction: Mononuclear macrophage/monocyte-lineage hematopoietic precursors differentiate into multinucleated osteoclasts. Abnormally increased numbers and/or overactivation of osteoclasts can lead to bone loss. Theref...
Heng Song,Gui-Zhen Ao,Huan-Qiu Li Heng Song
Introduction: Fatty acid biosynthesis is essential for the bacterial viability and growth. In recent years, β-ketoacyl-acyl carrier protein synthase III (FabH) become an attractive new target, which catalyzes the first s...
Barbara Rigby Barbara Rigby
Cells derived from human embryonic stem cells have great therapeutic potential. Patents are key to allowing companies that develop methods of generating such cells to recuperate their investment. However, in Europe, inventions relating to t...
Paulina Kosikowska,Adam Lesner Paulina Kosikowska
Introduction: Cathepsin G (CatG) is a neutral proteinase originating from human neutrophils. It displays a unique dual specificity (trypsin- and chymotrypsin-like); thus, its enzymatic activity is difficult to control. Ca...
Manasi Telang,Sivakami Dhulap,Anita Mandhare et al. Manasi Telang et al.
Introduction: Mangiferin, a natural C-glucoside xanthone [2-C-β-D-glucopyranosyl-1, 3, 6, 7-tetrahydroxyxanthone], is abundantly present in young leaves and stem bark of the mango tree. The xanthonoid structure of mangif...
Tobias G Kapp,Florian Rechenmacher,Tariq R Sobahi et al. Tobias G Kapp et al.
Introduction: Integrins are heterodimeric cell surface receptors, which enable adhesion, proliferation, and migration of cells by recognizing binding motifs in extracellular matrix (ECM) proteins. As transmembrane linkers...
John M Pezzuto,Tamara P Kondratyuk,Talysa Ogas John M Pezzuto
Introduction: There is currently a wealth of information on the effects of resveratrol and its derivatives in therapeutic, cosmetic and nutraceutical patent applications. Structure-activity studies of the resveratrol scaf...
Eduard Dolušić,Raphaël Frédérick Eduard Dolušić
Introduction: The inhibition of indoleamine 2,3-dioxygenase (IDO) has emerged as a key area in cancer immunotherapy in the past decade. Despite the large variety of potential inhibitors screened so far, the number of acti...