Pharmacological and biotechnological advances with Rosmarinus officinalis L [0.03%]
药用植物Rosmarinus officinalis L.的药理和生物技术研究进展
Josynaria Araújo Neves,Josyanne Araújo Neves,Rita de Cassia Meneses Oliveira
Josynaria Araújo Neves
Introduction: Rosmarinus officinalis L. is an aromatic plant with a number of biological properties. Recently, has been studied regarding its therapeutic potential. The objective of this study was to perform a systematic ...
Aminobenzisoxazole compounds as agonists of α7 nicotinic acetylcholine receptors: a patent evaluation (WO 2017027600) [0.03%]
激动α7乙酰胆碱烟碱受体的氨基苯并异噁唑化合物：一项专利评估（公布号：WO 2017027600）
Yang He,Jingshan Shen
Yang He
alpha 7 subtype nicotinic acetylcholine receptor (α7 nAChR) ligands, that is, ligands that interact with the orthosteric or allosteric binding sites of α7 nAChR, hold great potential for several therapeutic applications. Numerous compound...
Therapeutic potential of glycyrrhetinic acids: a patent review (2010-2017) [0.03%]
甘草酸的治疗潜力：专利综述(2010-2017)
Hidayat Hussain,Ivan R Green,Umair Shamraiz et al.
Hidayat Hussain et al.
Introduction: Glycyrrhetinic acids (GAs) viz., 18β-glycyrrhetinic acid and 18α-glycyrrhetinic acid, are oleanane-type triterpenes having a carboxylic acid group at C-30, and are extracted from the Chines herbal medicine...
Bioactivity and pharmacological properties of α-mangostin from the mangosteen fruit: a review [0.03%]
莽草酸的生物活性及药理作用：综述研究
Guoqing Chen,Yong Li,Wei Wang et al.
Guoqing Chen et al.
Introduction: α-Mangostin (α-MG) is the most representative xanthone isolated from the pericarp of mangosteen, possessing extensive biological activities and pharmacological properties, considered as an antineoplastic a...
Jae Eun Cheong,Anil Ekkati,Lijun Sun
Jae Eun Cheong
Introduction: Indoleamine 2,3-dioxygenase 1 (IDO1) is overexpressed by cancer cells and the antigen presenting dendritic cells in the tumor microenvironment (TME). Activation of IDO1 depletes tryptophan and produces kynur...
Corrigendum [0.03%]
勘误表
Published Erratum
Expert opinion on therapeutic patents. 2018 Mar;28(3):5. DOI:10.1080/13543776.2018.1437829 2018
Xinran Wang,Wei Li,Lijuan Hao et al.
Xinran Wang et al.
Introduction: Epidemiological studies have identified that high levels of low-density lipoprotein-cholesterol (LDL-C) and low levels of high-density lipoprotein-cholesterol (HDL-C) are two independent causes of cardiovasc...
Research and development of anti-Alzheimer's disease drugs: an update from the perspective of technology flows [0.03%]
抗阿尔茨海默症药物的研发：从技术流角度看最新进展
Kunmeng Liu,Hui-Heng Lin,Rongbiao Pi et al.
Kunmeng Liu et al.
Introduction: Today, over 20 million people suffer from Alzheimer's disease (AD) worldwide. AD has become a critical issue to human health, especially in aging societies, and therefore it is a research hotspot in the glob...
Current insights into anti-HIV drug discovery and development: a review of recent patent literature (2014-2017) [0.03%]
抗HIV药物研发的最近专利文献回顾（2014-2017）
Xiaofang Zuo,Zhipeng Huo,Dongwei Kang et al.
Xiaofang Zuo et al.
Introduction: To deal with the rapid emergence of drug resistance challenges, together with the difficulty to eradicate the virus, off-target effects and significant cumulative drug toxicities, it is still imperative to d...
Kate E Donald,K M Mohibul Kabir,William A Donald
Kate E Donald
Many commercial and academic institutions protect their commercially valuable research information using patents, making the patent literature a rich and early source of cutting-edge research. While scientists and students often create the ...