Corrigendum [0.03%]
勘误表
Published Erratum
Expert opinion on therapeutic patents. 2018 Jun;28(6):vii. DOI:10.1080/13543776.2018.1480336 2018
A patent review of butyrylcholinesterase inhibitors and reactivators 2010-2017 [0.03%]
2010-2017年丁酰胆碱酯酶抑制剂和复能剂专利综述
Vincenza Andrisano,Marina Naldi,Angela De Simone et al.
Vincenza Andrisano et al.
Introduction: Butyrylcholinesterase (BuChE) has obtained a renewed interest as therapeutic target in Alzheimer's disease (AD), when changes in BuChE activity and expression along disease progression were highlighted as we...
Amit Kumar Halder,Ana S Moura,M Natalia D S Cordeiro
Amit Kumar Halder
Introduction: Quantitative Structure-Activity Relationship (QSAR) models are becoming one of the most interesting fields for developing therapeutics and therapeutics related patents. At present, QSAR methodologies compris...
Benzoxaborole compounds for therapeutic uses: a patent review (2010- 2018) [0.03%]
用于药物用途的苯并恶硼唑化合物专利回顾(2010-2018)
Alessio Nocentini,Claudiu T Supuran,Jean-Yves Winum
Alessio Nocentini
Introduction: Benzoxaborole is a versatile boron-heterocyclic scaffold which has found in the last 10 years a broad spectrum of applications in medicinal chemistry, due to its physicochemical and drug-like properties. Use...
Camila Kiyomi Conegundes De Jesus,Mario Sergio Salerno
Camila Kiyomi Conegundes De Jesus
Introduction: Patents and patent portfolios are gaining attention in the last decades, from the called 'pro-patent era' to the recent billionaire transactions involving patent portfolios. The field is growing in importanc...
Indazole derivatives and their therapeutic applications: a patent review (2013-2017) [0.03%]
吲唑衍生物及其治疗应用（2013-2017）的专利评审
Ireen Denya,Sarel F Malan,Jacques Joubert
Ireen Denya
Introduction: Indazoles are heterocyclic moieties rarely found in nature. They are nitrogen containing chemical compounds composed of a pyrazole ring condensed with a benzene ring. Various indazole derivatives have been d...
Usnic acid and its derivatives for pharmaceutical use: a patent review (2000-2017) [0.03%]
专利点评：乌术酸及其衍生物在医药领域的应用（2000-2017）
Olga A Luzina,Nariman F Salakhutdinov
Olga A Luzina
Introduction: Usnic acid (UA) is a lichen-derived secondary metabolite with a unique dibenzofuran skeleton and is commonly found in lichenized fungi of the genera Usnea and Cladonia. Usnic acid has been incorporated for y...
Micaela Faria Freitas,Muriel Cuendet,Philippe Bertrand
Micaela Faria Freitas
Introduction: Zinc-dependent histone deacetylases (HDAC) inhibitors represent an important class of biologically active compounds with four of them approved by the FDA. A wide range of molecules has been reported for appl...
Valentina Sepe,Eleonora Distrutti,Stefano Fiorucci et al.
Valentina Sepe et al.
Introduction: The nuclear receptor FXR regulates the expression of genes involved in bile acids, glucose and lipid homeostasis. For its role as guardian of metabolism, FXR has been identified a promising pharmacological t...