Technological development of microemulsions with perspectives for pain treatment: a patent review [0.03%]
微乳技术发展及在疼痛治疗中的应用展望：专利分析
Marluce Pereira Damasceno Lima,Everton Moraes Lopes,Laércio da Silva Gomes et al.
Marluce Pereira Damasceno Lima et al.
Introduction: Microemulsions are thermodynamically stable translucent systems widely used for systemic delivery of drugs. The present study is the first to analyze the biotechnological potential of microemulsion systems f...
Site-specific delivery of polymeric encapsulated microorganisms: a patent evaluation of US20170165201A1 [0.03%]
聚合物封装微生物的位点特异性递送：对US20170165201A1专利的评估
Inderbir Singh,Pradeep Kumar,Viness Pillay
Inderbir Singh
Probiotics inculde live microorganisms therapeutically effective in the treatment of wide range of diseases. Probiotics possibly stimulates the growth of preferred microorganisms, crowds out potentially harmful microorganisms, and reinforce...
5-HT1A receptor ligands and their therapeutic applications: review of new patents [0.03%]
5-羟色胺1A受体配体及其治疗应用：新专利综述
Jakub Staroń,Ryszard Bugno,Adam S Hogendorf et al.
Jakub Staroń et al.
Introduction: 5-HT1AR was one of the first discovered serotonin receptors and is one of the most thoroughly studied. Dysfunctions associated with 5-HT1AR neurotransmission are linked to several psychiatric disorders, incl...
A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018) [0.03%]
PD-1/PD-L1拮抗剂专利分析：小分子、多肽及大环类拮抗剂（2015-2018）
Shabnam Shaabani,Harmen P S Huizinga,Roberto Butera et al.
Shabnam Shaabani et al.
Introduction: The protein-protein interaction PD1/PD-L1 is an important immune checkpoint and several recently approved monoclonal antibodies show promising anti cancer activities in the clinical practice. However, only a...
Arginine-lowering enzymes against cancer: a technocommercial analysis through patent landscape [0.03%]
基于专利图谱的降氨酸酶抗肿瘤技术商业化分析
Rakhi Dhankhar,Pooja Gulati,Sanjay Kumar et al.
Rakhi Dhankhar et al.
Introduction: Rise in incidence of various cancers and growing adoption of biological therapy to avoid side effects of conventional cancer therapies is driving the growth of the cancer biotherapy market globally. One such...
Innovative strategies in the diagnosis and treatment of tuberculosis: a patent review (2014-2017) [0.03%]
结核病诊断与治疗的创新策略专利盘点(2014-2017)
Tulshidas S Patil,Ashwini S Deshpande
Tulshidas S Patil
Introduction: Tuberculosis (TB) is a disease caused due to an infection of Mycobacterium tuberculosis (M TB) bacilli affecting millions of people worldwide. It is the ninth leading cause of death and ranks above the HIV/A...
Juliana Santos-Gandelman,Márcio Lourenço Rodrigues,Alice Machado Silva
Juliana Santos-Gandelman
Introduction: Cryptococcosis is one of the most devastating human fungal infections. Despite its impact, none of the standard antifungals were developed after 1990. New, improved, less toxic, affordable and widely availab...
Carbonic anhydrase inhibitors as antitumor/antimetastatic agents: a patent review (2008-2018) [0.03%]
碳酸酐酶抑制剂作为抗肿瘤/抗转移药物的专利回顾（2008-2018）
Alessio Nocentini,Claudiu T Supuran
Alessio Nocentini
Introduction: Human carbonic anhydrases (CA, EC 4.2.1.1) IX and XII are tumor-associated proteins, being part of the molecular machinery that tumor cells build as adaptive responses to hypoxia and acidic conditions charac...
Evaluation of WO2017018805: 1,3,4-oxadiazole sulfamide derivatives as selective HDAC6 inhibitors [0.03%]
WO2017018805评估：1,3,4-噁二唑素胺衍生物作为选择性HDAC6抑制剂的效果
Yuan-Yuan Liang,Cheng-Mei Zhang,Zhao-Peng Liu
Yuan-Yuan Liang
There are great potential in the development of selective HDAC6 inhibitors for the treatment of infectious diseases, neoplasms, endocrine diseases, and other diseases associated with HDAC6 activity. Areas covered: The application claims 1,3...
Circulating miRNAs as biomarkers for early diagnosis of coronary artery disease [0.03%]
循环miRNA作为冠状动脉疾病早期诊断生物标志物的潜力
Lei Zhang,Yuan Zhang,Yanfang Zhao et al.
Lei Zhang et al.
Introduction: Coronary artery disease (CAD) contributes to a huge number of human death worldwide. The early diagnosis can arrest the development of CAD and effectively lower the mortality rate. Recently, circulating miRN...