Peroxisome Proliferator-Activated Receptor agonists and antagonists: an updated patent review (2020-2023) [0.03%]
过氧化物酶体增殖激活受体激动剂和拮抗剂专利回顾(2020-2023)更新版
Barbara De Filippis,Arianna Granese,Alessandra Ammazzalorso
Barbara De Filippis
Introduction: The search for novel compounds targeting Peroxisome Proliferator-Activated Receptors (PPARs) is currently ongoing, starting from the previous successfully identification of selective, dual or pan agonists. I...
Successes and challenges in the development of BD1-selective BET inhibitors: a patent review [0.03%]
BD1选择性BET抑制剂开发中的成功与挑战:一项专利回顾
Monica Viviano,Alessandra Cipriano,Emanuele Fabbrizi et al.
Monica Viviano et al.
Introduction: Bromodomain and ExtraTerminal (BET) domain proteins are transcriptional cofactors that, recognizing acetylated lysines of histone and non-histone proteins, can modulate gene expression. The BET family consis...
Targeting the EGFR/RAS/RAF signaling pathway in anticancer research: a recent update on inhibitor design and clinical trials (2020-2023) [0.03%]
EGFR/RAS/RAF信号通路在抗癌研究中的靶向治疗:抑制剂设计及临床试验最新进展(2020-2023年)
Rima Hajjo,Dima A Sabbah,Sanaa K Bardaweel et al.
Rima Hajjo et al.
Introduction: Recent years have seen significant strides in drug developmenttargeting the EGFR/RAS/RAF signaling pathway which is critical forcell growth and proliferation. Protein-protein interaction networksamong EGFR, ...
Recent developments of agents targeting Vibrio cholerae: patents and literature data [0.03%]
针对霍乱弧菌的药物最新发展:专利和文献数据
Francesco Melfi,Simone Carradori,Noemi Mencarelli et al.
Francesco Melfi et al.
Introduction: Vibrio cholerae bacteria cause an infection characterized by acute diarrheal illness in the intestine. Cholera is sustained by people swallowing contaminated food or water. Even though symptoms can be mild, ...
Therapeutic cysteine protease inhibitors: a patent review (2018-present) [0.03%]
治疗性半胱氨酸蛋白酶抑制剂:专利回顾(2018年至今)
Giulia Barchielli,Antonella Capperucci,Damiano Tanini
Giulia Barchielli
Introduction: Cysteine proteases are involved in a broad range of biological functions, ranging from extracellular matrix turnover to immunity. Playing an important role in the onset and progression of several diseases, i...
Recent developments of HSP90 inhibitors: an updated patent review (2020-present) [0.03%]
HSP90抑制剂的 recent developments: 一项更新的专利回顾(2020年至今)
注:这里的"recent developments"翻译为“最新发展”可能更符合中文表达习惯,但原文中的词语顺序被调整以符合中文语法。如果要严格按字面意思翻译,则可以译为:“HSP90抑制剂的近期发展: 一项更新的专利回顾(2020年至今)” 。考虑到语义和通顺度,“最新”可能更合适。
因此,推荐版本为:
HSP90抑制剂的最新发展:2020年以来的专利综述
Jianfeng Liu,Huangliang Shu,Qinxin Xia et al.
Jianfeng Liu et al.
Introduction: The 90-kDa heat shock protein (HSP90) functions as a molecular chaperone, it assumes a significant role in diseases such as cancer, inflammation, neurodegeneration, and infection. Therefore, the research and...
Photodynamic therapy alone or in combination to counteract bacterial infections [0.03%]
光动力疗法单独使用或联合使用以对抗细菌感染
Sébastien Clément,Jean-Yves Winum
Sébastien Clément
Introduction: Antibacterial photodynamic therapy presents a promising alternative to antibiotics, with potential against multidrug-resistant bacteria, offering broad-spectrum action, reduced resistance risk, and improved ...
Antimo Gioiello,Emiliano Rosatelli,Bruno Cerra
Antimo Gioiello
Introduction: The Farnesoid X receptor (FXR) is a key transcription factor that is involved in the bile acid signaling network. The modulation of the FXR activity influences glucose and lipid homeostasis, reduces obesity ...
The patent review of the biological activity of tropane containing compounds [0.03%]
含托品烷生物碱类化合物的生物活性专利评述
Thoraya A Farghaly,Ghada S Masaret,Hanan Gaber Abdulwahab
Thoraya A Farghaly
Introduction: Tropane-derived medications have historically played a substantial role in pharmacotherapy. Both natural and synthetic derivatives of tropane find application in addressing diverse medical conditions. Promin...
Therapeutic applications of thymosin peptides: a patent landscape 2018-present [0.03%]
胸腺肽的治疗应用:2018年至今的专利概览
Michael Quagliata,Anna Maria Papini,Paolo Rovero
Michael Quagliata
Introduction: Thymosins are small proteins found mainly in the thymus. They are involved in several biological processes, including immunoregulation, angiogenesis, and anti-inflammatory activity. Due to these multiple act...