Phenolic compounds from Origanum majorana with biofilm-inhibitory activity against methicillin-resistant Staphylococcus aureus and Escherichia coli strains [0.03%]
百里香酚马郁兰化学成分抗甲氧西林金黄色葡萄球菌和大肠杆菌生物膜活性研究
Annamária Kincses,Tasneem Sultan Abu Ghazal,Katalin Veres et al.
Annamária Kincses et al.
Context: Antibiotic resistance in bacteria is a growing global problem, with biofilm formation and efflux pumps playing crucial roles in this issue. Objec...
Apigenin attenuates the atherosclerotic lesions through enhancing selective autophagy/lipophagy and promoting RCT process [0.03%]
阿皮根素通过增强选择性自噬/脂自噬和促进RCT过程来缓解动脉粥样硬化病变
Zixuan Hu,Yuting Li,Nan Yao et al.
Zixuan Hu et al.
Context: Apigenin, a naturally flavonoid, is reported to have protective effects in chronic and metabolic diseases. But the therapeutic or ameliorative effects of apigenin on atherosclerosis are not known. ...
A triterpene-enriched natural extract from Eucalyptus tereticornis modulates the expression of genes involved in adipogenesis, lipolysis, and extracellular matrix remodeling in a primary human and mouse cell line adipocyte [0.03%]
Eucalyptus tereticornis富含三萜类天然提取物调节参与人类和小鼠原代细胞系脂肪细胞中肥胖相关基因的表达
Sergio Acin,Alejandro Mejia-Garcia,Geysson Javier Fernandez et al.
Sergio Acin et al.
Context: Obesity induces alterations in adipocyte size, tissue inflammation, vascularization, and extracellular matrix composition. Previous studies have shown that a leaf extract of Eucalyptus tereticornis Sm. (Myrtaceae...
Mark J Tallon,Robert B Child,Jason L Blum
Mark J Tallon
Context: As a naturally occurring terpenoid found in Cannabis sativa L. (Cannabaceae), cannabidiol (CBD) has gained public and industry interest for the purposes of personal well-being as a foodstuff and pharmaceutical. D...
Carynn Tanbuda,Mazdida Sulaiman,Pauline Yong Pau Lin et al.
Carynn Tanbuda et al.
Context: The discovery of plants and bioactive compounds with the potential to become botanical or pharmaceutical drugs remains a cornerstone of drug innovation. Many of these valuable molecules originate from traditional...
Delivery of small interfering RNA through lyophilized natural lipid nanoparticles: effects of natural lipid selection [0.03%]
通过冻干天然脂质纳米颗粒递送小干扰RNA：天然脂质选择的影响
Hangjie Wang,Wei Li,Junyan Chen et al.
Hangjie Wang et al.
Context: Lipid nanoparticles (LNPs) are the primary non-viral vectors for siRNA delivery. However, synthetic lipids face issues, such as low lysosomal escape efficiency and high cost. ...
Mayuramas Sang-Ngern,Ashley Fukuchi,Tamara P Kondratyuk et al.
Mayuramas Sang-Ngern et al.
Context: Physalis peruviana L. (Solanaceae), also known as Poha, has been used in traditional medicine since pre-Columbian times, particularly in treating cancer. ...
Involvement of ionomic metabolism of both the cerebrospinal fluid and the spinal cord in the analgesic efficacy of matrine in rats [0.03%]
苦参碱在大鼠镇痛作用中脑脊液和脊髓离子组学代谢的参与
Jin-Lu Huang,Chen-Yue Tang,Yao Fu et al.
Jin-Lu Huang et al.
Context: Matrine has antinociceptive properties, and spinal cord ionomic changes are involved in bone cancer pain. Objective: To invest...
Anti-fibrosis effect of astragaloside IV in animal models of cardiovascular diseases and its mechanisms: a systematic review [0.03%]
黄芪苷IV在心血管疾病动物模型中的抗纤维化作用及其机制的系统评价
Shiyu Zhang,Shijie Li,Xue Li et al.
Shiyu Zhang et al.
Context: Myocardial fibrosis is a common manifestation of end-stage cardiovascular disease, but there is a lack of means to reverse fibrosis. Astragaloside IV (AS-IV), the major active component of Astragalus membranaceus...
Yiqi Wenyang decoction protects against the development of atherosclerosis by inhibiting vascular inflammation [0.03%]
一气温阳汤通过抑制血管炎症反应防治动脉粥样硬化病变
Shuang Hua,Lingling Sun,Han Zhang et al.
Shuang Hua et al.
Context: Vascular inflammation is a key process in the pathogenesis of atherosclerosis, which is regulated by NF-κB pathway. Yiqi Wenyang decoction (YQWY), a Traditional Chinese medicine (TCM) formula, has anti-inflammat...