Kaempferol activity on Cryptosporidium parvum infection in an experimentally infected immunocompromised mouse model: In silico and in vivo investigations [0.03%]
kaempferol对克鲁氏隐孢子虫感染的免疫缺陷小鼠模型的作用：计算机模拟和体内研究
Majed H Wakid,Eman S El-Wakil,Muslimah N Alsulami et al.
Majed H Wakid et al.
Context: No vaccine or effective therapy for cryptosporidiosis currently exists, except for nitazoxanide (NTZ), which has limited effectiveness in immunocompromised hosts. Kaempferol (KPF), a naturally occurring flavonoid...
Comparative Study
Pharmaceutical biology. 2026 Dec;64(1):27-45. DOI:10.1080/13880209.2025.2603384 2026
(±)-Rutacycoumarins A and B: two pairs of unprecedented coumarin enantiomers from the aerial part of Ruta graveolens L. and chemically synthesized [0.03%]
rutagraveolens的(+/-)RUTACYCOUMARINS A和B：一对前所未有的香豆素型对映体及其化学合成
Xu Feng,Jing Fang,Yanyang Liu et al.
Xu Feng et al.
Context: Benzofuran derivatives are important structural motifs found in natural products, often exhibiting significant biological activities. Ruta graveolens L. is a plant source known for containing diverse bioactive co...
Graveoumarins A-C: chiral resolution, absolute configuration, and anticoagulant/anti-inflammatory activities of 3'-methyl-3'-butenyl coumarins from ruta graveolens L [0.03%]
牻牛儿苗内酯A-C：牻牛儿苗中的牻牛儿基甲氧基肉桂酰型香豆素的对映异构体拆分、绝对构型及其抗凝血/抗炎活性研究
Zhihao Wu,Xiaolin Liao,Yuxin Wang et al.
Zhihao Wu et al.
Context: Several coumarins have been isolated from Ruta graveolens L., but the chirality of many remains uncharacterized or their absolute configurations unresolved. ...
From kratom to 7-hydroxymitragynine: evolution of a natural remedy into a public-health threat [0.03%]
从坤蒂安到乌头木因-7β-氧基酮：一种天然疗法向公共健康威胁的转变
Scott Alsbrook,George Pro,Igor Koturbash
Scott Alsbrook
Context: Kratom (Mitragyna speciosa), native to Southeast Asia, has traditionally been consumed as fresh leaves or teas. Under those conditions, exposure to 7-hydroxymitragynine (7-OH)-a potent μ-opioid receptor agonist-...
Hepatotoxicity of dietary supplements containing Garcinia gummi-gutta (L.) N. Robson [0.03%]
含加利果提取物(Garcinia gummi-gutta)的膳食补充剂导致肝毒性
Richard B van Breemen,Amy L Roe,Nadeem Akhtar
Richard B van Breemen
Background: Botanical dietary supplements derived from the fruit of the tree Garcinia gummi-gutta (L.) N. Robson (commonly known as Garcinia cambogia or Garcinia) are used to support weight loss but are increasingly linke...
An exploratory evaluation of the interaction risk between herbal products and pharmaceutical medicines used concurrently for disease management in Blantyre, Malawi [0.03%]
马拉维兰塔尼尔市同时使用草药产品和药物治疗疾病时的相互作用风险的探索性评估
Kumbukani K Nyirenda,John Mponda,Ibrahim Chikowe et al.
Kumbukani K Nyirenda et al.
Context: The use of herbal products in Malawi remains widespread and culturally significant, often occurring alongside pharmaceutical medicine treatments. As the burden of non-communicable diseases such as diabetes and hy...
Potential pharmacological quality control markers in the traditional Japanese medicine Hangeshashinto: identifying anti-inflammatory ingredients through a cell-based bioassay and multicomponent analysis [0.03%]
汉解散痛汤的潜在药理质量控制标志物：通过细胞活性测定和多组分分析鉴定抗炎成分
Ryota Imai,Yuta Muraki,Akinori Nishi et al.
Ryota Imai et al.
Context: The traditional Japanese medicine Hangeshashinto (HST) is a multicompound drug used for stomatitis. The identification of HST's active ingredients is essential for understanding its mechanism of action and establ...
Cedrol prevents UVB-induced photoaging by restoring mitochondrial function, metabolic homeostasis, and skin barrier integrity in HaCaT cells [0.03%]
香芹醇通过恢复HaCaT细胞的线粒体功能、代谢稳态和皮肤屏障完整性来预防UVB引起的光老化
Mo-Rong Xu,Chia-Hsin Lin,Hsun-Hua Lee et al.
Mo-Rong Xu et al.
Context: Ultraviolet B (UVB) radiation is a key environmental contributor to skin photoaging, primarily by inducing oxidative stress, mitochondrial dysfunction, metabolic imbalance, and downregulation of tight junction (T...
Exploring chemical composition, anti-acetylcholinesterase, and anticancer activities of Pistacia atlantica Desf [0.03%]
帕西塔亚塔尼克Desf的化学成分、抗乙酰胆碱酯酶和抗癌活性研究
Chahrazad Bakka,Huseyin Akşit,Wafa Zahnit et al.
Chahrazad Bakka et al.
Context: The Atlas Pistachio (Pistacia atlantica Desf.) possesses numerous applications for therapeutic purposes. Objective: We set out...
Constance A Mitchell,Amy L Roe,Scott Auerbach et al.
Constance A Mitchell et al.
Context: Botanicals, including products derived from plants, fungi, and algae, are increasingly consumed worldwide. Their complex compositions and variable phytochemical profiles present significant challenges for safety ...