Reduced lipid and glucose oxidation and reduced lipid synthesis in AMPKα2-/- myotubes [0.03%]
AMPKα2缺失肌管中降低的脂质和葡萄糖氧化及减少的脂质合成
Christine Skagen,Stanislava Stevanovic,Hege Gilbø Bakke et al.
Christine Skagen et al.
Adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) plays a crucial role in regulation of metabolic homeostasis. To understand the role of the catalytic α2 subunit of AMPK in skeletal muscle energy metabolism, myotube cultures...
Lipophagy: exploring its association with male reproductive system disorders and investigating potential mechanisms [0.03%]
脂噬作用：探索其与男性生殖系统疾病的关系及潜在机制研究
Wanyi Chen,Jin Chen,Ziqiong Cheng et al.
Wanyi Chen et al.
Background: Lipid metabolism, one of the three major metabolic processes, plays a crucial role in male fertility, particularly when lipid homeostasis is disrupted. Lipid droplets (LDs), cellular organelles that store lipi...
Melatonin improves adverse vascular remodelling and redox homeostasis in monocrotaline-induced pulmonary arterial hypertension [0.03%]
褪黑素改善单端孢霉烯诱导的肺动脉高压患者的血管重构及氧化应激稳态失调
Silvio Tasca,Patrick Türck,Daniela Drosdowski et al.
Silvio Tasca et al.
This study explored the effects of melatonin on cardiac and vascular function, and redox homeostasis in model PAH. Male Wistar rats were divided into: control (CTR), monocrotaline [MCT (60 mg/kg, single dose i.p)], monocrotaline + sildenafi...
Boldine reduces left ventricle oxidative stress in isoproterenol-induced adrenergic overload experimental model [0.03%]
番木鳖碱减少异丙肾上腺素致心脏去甲肾上腺素负荷模型大鼠左室氧化应激作用研究
Elissa Kerli Fernandes,Patrick Türck,Cristina Campos Carraro et al.
Elissa Kerli Fernandes et al.
Sustained adrenergic overload in the heart causes maladaptive cardiac remodelling, which involves oxidative stress. Boldine (BOL) has antioxidant activity and represents a novel therapeutic approach. This study explored the cardioprotective...
Correction [0.03%]
改正 ошибки
Published Erratum
Archives of physiology and biochemistry. 2024 Nov 23:1. DOI:10.1080/13813455.2024.2432763 2024
Cytotoxic properties of Thuya occidentalis hydroalcoholic extract on androgen unresponsive prostate cancer cells [0.03%]
thuja occidentalis 水醇提取物对雄激素非依赖性前列腺癌细胞的细胞毒性作用
Gabriela Elisa Hirsch,Mariana Migliorini Parisi,Leo Anderson Meira Martins et al.
Gabriela Elisa Hirsch et al.
Background: Androgen independent phase in prostate cancer (PCa) commonly limits the therapeutic efficacy. Thuya occidentalis through its main active compound, α-thujone, appears to be an option, considering its anti-proliferative, anti-met...
Neem seed oil ameliorates diabetic phenotype by suppressing redox imbalance, dyslipidaemia and pro-inflammatory mediators in a rodent model of type 2 diabetes [0.03%]
印度苦楝种子油通过抑制氧化还原失衡、脂质异常和促炎介质来改善2型糖尿病动物模型的糖尿病表现型
Bartholomew I C Brai,Ruth Ometere Joseph,Titilope Ruth Komolafe et al.
Bartholomew I C Brai et al.
The neem plant (Azadirachta indica) has popular ethnomedicinal applications. The anti-diabetic potential and mechanism of neem seed oil (NSO) in a rodent model of type 2 diabetes mellitus was evaluated in the present study. Experimentally-i...
Triglycerides and metabolic syndrome: from basic to mechanism - A narrative review [0.03%]
三酰甘油与代谢综合征：从基础到机制——综述文章
Gayathri S Prabhu,Preethi Lavina Concessao
Gayathri S Prabhu
Content: The impact of triglyceride levels is important to understand the changes in metabolism and structure. With an increase in obesity and hyperlipidemia due to diet; cardiovascular and neuronal structural changes hav...
AMPK activation; a potential strategy to mitigate TKI-induced cardiovascular toxicity [0.03%]
激活AMPK；减轻酪氨酸激酶抑制剂诱导的心血管毒性的潜在策略
Nasser Safaie,Gholamreza Idari,Diba Ghasemi et al.
Nasser Safaie et al.
The introduction of Tyrosine Kinase Inhibitors (TKIs) has revolutionised cancer treatment, yet concerns regarding cardiovascular toxicity have surfaced. This piece delves into the interplay between AMP-activated protein kinase (AMPK) signal...
Beclin1/LC3II/P62 autophagy pathway activation is involved in the protective action of C-peptide against prostate injury in a rat model of type 1 diabetes [0.03%]
C-肽通过激活Beclin1/LC3 II/P62自噬途径保护1型糖尿病大鼠前列腺损伤的作用及机制研究
Heba A Abdel-Hamid,Manar Fouli Gaber Ibrahim,Doaa Mohamed Elroby Ali et al.
Heba A Abdel-Hamid et al.
One of the undesirable complications of diabetes is sexual dysfunctions in males which may affect their fertility. This research aims to study the effect of C-peptide administration on the prostate of diabetic rats and focusing on exploring...