Disrupting of tissue-resident FOLR2+tumour-associated macrophages-derived interleukin-10 improves anti-PD-1 efficacy in gastric cancer [0.03%]
胃癌中扰乱组织常驻FOLR2+tumor associated macrophages来源的IL-10可增强抗PD-1疗效
Anwei Xue,Yifan Cao,Kuan Yu et al.
Anwei Xue et al.
Background: Our previous studies have demonstrated monocyte-derived tumour-associated macrophages (TAMs) secret CXCL8, which induces autonomous PD-L1 expression resulting in immune suppressive microenvironment. However, t...
Gut blautia coccoides-derived 5Z-dodecenoic acid attenuates chronic psychological stress-induced gastric cancer progression [0.03%]
肠道乳球菌属短杆菌衍生的反式亚油酸(att)可通过调控色氨酸代谢途径减轻慢性心理压力诱导的胃癌进展
Ruiyang Zhao,Yuyuan Lu,Qixuan Xu et al.
Ruiyang Zhao et al.
Background: Chronic psychological stress is a critical oncogenic factor of gastric cancer (GC). However, the mechanisms underlying stress-induced malignant progression remain largely unknown. Gut microbiota dysregulation ...
Triple adjuvant therapy with transarterial chemoembolizaition, lenvatinib, and programmed death-1 inhibitors improves short-term recurrence control in high-risk patients with resected intermediate-stage hepatocellular carcinoma [0.03%]
经动脉化疗栓塞、仑伐替尼和程序性死亡-1抑制剂三联辅助治疗可改善中期肝细胞癌切除患者短期复发控制效果
Guanhua Chen,Yiwen Qiu,Shu Shen et al.
Guanhua Chen et al.
Background: Intermediate-stage hepatocellular carcinoma (HCC) following curative liver resection (LR) is associated with high recurrence rates and poor survival outcomes. Current studies have found that transarterial chem...
Surgical resection outperforms chemoradiation in HPV-associated mucinous adenocarcinoma of the cervix: a SEER-based survival analysis [0.03%]
基于SEER的生存分析提示手术切除可优于放化疗成为HPV相关宫颈粘液腺癌的主要治疗手段
Jiamei Lu,Lin Lin,Xinru Li et al.
Jiamei Lu et al.
Objective: Given the rarity of human papillomavirus-associated mucinous adenocarcinoma (HPVAM) of the cervix and the lack of established clinical treatment guidelines, there is uncertainty regarding optimal clinical manag...
Survival benefit of radiotherapy in pancreatic cancer A real-world analysis based on SEER and an independent hospital-based cohort [0.03%]
基于SEER和独立医院队列的胰腺癌放射治疗生存获益的实证分析研究
Yanglong Ou,Yedong Huang,Zhe Zhang et al.
Yanglong Ou et al.
Background: Pancreatic cancer remains one of the most lethal malignancies worldwide, and the role of radiotherapy in improving prognosis remains controversial. This study aimed to assess the survival benefit of radiothera...
Hilar cholangiocarcinoma surgery: a decade of bibliometric insights into open vs. minimally invasive global trends (2015-2024) [0.03%]
hilar胆管癌手术：开放手术与微创手术全球趋势的文献计量学见解（2015-2024年）
Yichen Wu,Haibo Xu,Zhiming Hu et al.
Yichen Wu et al.
Exploring the prognostic utility of large language models versus traditional clinical models in heart failure: a pilot study [0.03%]
探索大型语言模型与传统临床模型在心力衰竭预后效用的试点研究
Luxiang Shang,Yali Chen,Rui Li et al.
Luxiang Shang et al.
Background: Large language models (LLMs) show promise in clinical decision support; however, their role in risk prediction for heart failure (HF) remains uncertain. ...
CBCT-guided robotic cochlear implantation precision, efficiency, and procedural standardization in a preclinical study [0.03%]
基于CBCT的机器人听觉脑干植入术精准性、高效性和操作标准化的耳科学前研究
Zibo Li,Miao Zhang,Hengjia Liu et al.
Zibo Li et al.
Objective: Cochlear implantation (CI) requires submillimeter precision to protect delicate inner ear structures. This preclinical study assesses a novel cone-beam computed tomography (CBCT)-guided robotic system for CI, a...
The dynamic changes and precise classification of parathyroid function within one year after thyroid cancer surgery [0.03%]
甲状腺癌手术后一年内甲状旁腺功能的动态变化及精准分类
Kang Ning,Yarong Liang,Taonong Cai et al.
Kang Ning et al.
Background: Postoperative parathyroid dysfunction is a common complication of thyroid surgery. However, the temporal pattern of postoperative parathyroid function and standardized clinical interventions remain poorly defi...