Neuronal PD-L1 suppression attenuates ischemic stroke injury via PD-1/RFX1 axis-mediated microglial polarization [0.03%]
神经元PD-L1抑制通过PD-1/RFX1轴介导的小胶质细胞极化减轻缺血性脑卒中损伤
Fangyuan Cheng,Bo Yan,Han Gao et al.
Fangyuan Cheng et al.
Background and purpose: The role of PD-L1/PD-1 axis in IS remains controversial, with conflicting outcomes from systemic PD-1 or PD-L1 knockout models. These discrepancies underscore the complexity of PD-L1/PD-1 signaling...
Surgical approach, preoperative LEEP/conization and patterns of recurrence and death in low-risk cervical cancer - exploratory analysis from the CCTG CX.5/SHAPE trial [0.03%]
宫颈癌的手术方式、术前LLETZ/Cone切以及低风险患者复发和死亡模式-CCTG CX.5/SHAPE试验探索性分析
Sven Mahner,Fabian Trillsch,Janice S Kwon et al.
Sven Mahner et al.
Background: SHAPE demonstrated that simple hysterectomy was not inferior to radical hysterectomy in patients with low-risk cervical cancer. To further understand the role of preoperative LEEP/conization, clear LEEP/coniza...
Lifestyle, genetic susceptibility, and risk of diverticular disease: a prospective cohort study [0.03%]
生活方式、遗传易感性和 diverticulosis发病风险：前瞻性队列研究
Chuan-Guo Guo,Jiaxin Wang,Yufan Liu et al.
Chuan-Guo Guo et al.
Background: Emerging evidence indicates diverticular disease is attributed to both environmental and genetic factors. The impact of modifiable lifestyle factors on diverticular disease has not been fully elucidated, parti...
A commentary on "Brain-computer interfaces: the innovative to unlocking neurological conditions" [0.03%]
《脑机接口：解锁神经系统的创新工具》一文述评
Chen Fan,Yuan Ding,Hongri Zhang
Chen Fan
Pre-clinical therapeutics for osteopetrosis caused by PLEKHM1 deficiency Using ex Vivo and in vivo gene Therapies [0.03%]
用于由PLEKHM1缺陷引起的骨髓疾病在体外和体内基因治疗的药物研究
Jie Jiang,Yang Tian,Zhao He et al.
Jie Jiang et al.
Background: Osteopetrosis caused by mutation of Plekhm1 gene is characterized by malignant phenotypes, poor quality of life, and lack of effective treatment. It remains in dispute whether hematopoietic stem cell transplan...
A meta-analysis of changes in Gut microbiota structure following bariatric surgery [0.03%]
代谢手术对肠道微生物群结构改变的meta分析研究论文发表
Min Chen,Tai-Chun Tang,Yao-Yao Chen et al.
Min Chen et al.
Background: Bariatric surgery is a common intervention for obesity, yet its impact on gut microbiota remains unclear. Objective: This s...
Reevaluating drivers of endometriosis burden: a call for deeper contextualization [0.03%]
重新评估子宫内膜异位症负担的影响因素：深入情境分析的呼吁
Haoyuan Li,Haiying Fan,Yiwen Yang
Haoyuan Li
Neoadjuvant chemoimmunotherapy in resectable locally advanced oral squamous cell carcinoma [0.03%]
可切除的局部晚期口腔鳞癌的新辅助化疗免疫治疗
Wang Shuhan,Dong Gang,Ma Xiangrui
Wang Shuhan
Establishing trauma databases in underserved regions: a call to action for advancing data-driven surgical quality improvement [0.03%]
在医疗资源匮乏地区建立创伤数据库：推进基于数据的外科质量改进的行动号召
Cherinet D Osebo,Lilly Groszman,Alexander Laskaris et al.
Cherinet D Osebo et al.