Multi-omic profiling reveals age-specific blood biomarkers and aging-driven B Cell remodeling in osteoarthritis [0.03%]
多组学谱型分析揭示了骨关节炎的年龄特异性血液生物标志物和衰老驱动的B细胞重塑
Bizhi Tu,Run Fang,Peizhi Lu et al.
Bizhi Tu et al.
Background: Osteoarthritis (OA) pathogenesis involves age-related immune dysregulation, yet non-invasive diagnostic tools and mechanistic insights remain limited. ...
Preoperative blood-brain barrier disruption increased risk of postoperative cognitive decline after coronary artery bypass grafting: a prospective cohort study [0.03%]
冠脉旁路移植术前血脑屏障破坏增加术后认知功能障碍风险：一项前瞻性队列研究
Weijing Wang,Sen Zhang,Lu Yu et al.
Weijing Wang et al.
Background: Cognitive decline after coronary artery bypass grafting (CABG) surgery is common and significantly impacts the long-term prognosis of coronary artery disease (CAD) patients. Nevertheless, the mechanisms of pos...
Mindfulness in surgeons [0.03%]
外科医生的正念冥想
Valentina Bianchi,Carmen Nesci,Filomena Misuriello et al.
Valentina Bianchi et al.
Snapshot cohort study on early-onset colorectal cancer in Northwestern Switzerland - are we doing enough or can we do more? [0.03%]
西北瑞士早期结直肠癌快照队列研究——我们做得够多了吗？还可以做些什么？
Suna Erdem,Hélène Gros,Jörn-Markus Gass et al.
Suna Erdem et al.
Background: Early-onset colorectal cancer (EOCC), defined as CRC in patients under 50, is rising alarmingly in Western countries. This study explores key differences in clinical profiles, socioeconomic factors, and oncolo...
Global Disparities in Healthcare Resources and Cancer Burden: A Population-based Systematic Analysis of 171 Countries in 2022 [0.03%]
全球医疗资源差异与癌症负担：基于人口的171个国家/地区的系统分析（2022年）
Qian Zhu,Kexin Sun,Yifei Yao et al.
Qian Zhu et al.
Background: Global disparities in healthcare resources impact diagnosis, treatment, and ongoing supportive care for cancer. As these resource levels can be considered modifiable factors of health inequality on a global sc...
Safety, efficacy, and quality of life following Sphinkeeper™ implantation for fecal incontinence: a multicenter retrospective cohort study with mid-term follow-up [0.03%]
SphinkeeperTM植入治疗大便失禁的中期随访多中心回顾队列研究：安全性、有效性和生活质量的影响
Luigi Brusciano,Antonio Brillantino,Luigi Marano et al.
Luigi Brusciano et al.
Background: Sphinkeeper™ (SK) implantation has emerged as a minimally invasive option for patients with fecal incontinence (FI) who fail to respond to conservative therapies. While preliminary outcomes have been encourag...
Molecular characterization of breast cancer and multiple primary malignancies: the latest application using unmarked quantitative proteomics [0.03%]
乳腺癌和多原发恶性肿瘤的分子特征：未标记定量蛋白质组学的最新应用
Ping Wang,Shuang Liang,Huiting Zhang et al.
Ping Wang et al.
Background: Breast cancer remains the most prevalent malignancy among women, and patients presenting with both breast and lung cancer pose significant challenges in clinical diagnosis and treatment. Currently, comprehensi...
Bridging single-cell insights to clinical translation in slow transit constipation: integrating digital innovations [0.03%]
单细胞技术在慢传输型便秘的临床转化研究中大有可为：数字创新整合助力前行
Yuze Zhai,Li Li,Guoliang Wu
Yuze Zhai
Integrating clinical-pathological-MRI features to construct a prediction model for pathological complete remission of axillary lymph nodes after neoadjuvant therapy: a retrospective study [0.03%]
基于临床病理MRI特征构建新辅助治疗后腋窝淋巴结病理完全缓解的预测模型：回顾性研究
Jiabei Shang,Jianzhe Chen,Xudong Gao et al.
Jiabei Shang et al.
Background: Accurate assessment of axillary lymph node (ALN) metastasis is essential for developing an effective treatment strategy for breast cancer (BC). Despite advancements in imaging and surgical techniques, a critic...
Kaijie Qiu,Canlong Wang,Xianan Mo et al.
Kaijie Qiu et al.
Background: Previous literature lacks comprehensive reporting on the economic burden of musculoskeletal disorders (MSDs). Our objective was to report the macroeconomic burden of MSDs, and their subcategories, including rh...