Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas [0.03%]
复发性恶性胶质瘤治疗过程中脑脊液基质金属蛋白酶-9水平升高
Eric T Wong,David Alsop,Diana Lee et al.
Eric T Wong et al.
Background: Matrix metalloproteinases (MMPs) are enzymes that promote tumor invasion and angiogenesis by enzymatically remodeling the extracellular matrix. MMP-2 and MMP-9 are the most abundant forms of MMPs in malignant ...
Expression of junctional proteins in choroid plexus epithelial cell lines: a comparative study [0.03%]
脉络丛上皮细胞系连接蛋白的表达及比较研究
Joanna Szmydynger-Chodobska,Crissey L Pascale,Andrew N Pfeffer et al.
Joanna Szmydynger-Chodobska et al.
Background: There is an increasing interest in using choroid plexus (CP) epithelial cell lines to study the properties of the blood-cerebrospinal fluid barrier (BCSFB). Currently, there are three major CP-derived cell lin...
Evaluation of the IS6110 PCR assay for the rapid diagnosis of tuberculous meningitis [0.03%]
评估IS6110 PCR试验快速诊断结核性脑膜炎的价值
Poonam S Deshpande,Rajpal S Kashyap,Sonali S Ramteke et al.
Poonam S Deshpande et al.
Background: Tuberculous meningitis (TBM) is one of the common clinical manifestations of extra-pulmonary tuberculosis. It is difficult to diagnose due to a lack of rapid, sensitive, and specific tests. Newer methods, whic...
Protein and synthetic polymer injection for induction of obstructive hydrocephalus in rats [0.03%]
大鼠蛋白质和合成高分子诱导阻塞性脑积水模型的建立
Ili Slobodian,Dmitri Krassioukov-Enns,Marc R Del Bigio
Ili Slobodian
Background: The objective of this study was to develop a simple and inexpensive animal model of induced obstructive hydrocephalus with minimal tissue inflammation, as an alternative to kaolin injection. ...
Ion channel diversity, channel expression and function in the choroid plexuses [0.03%]
脑室脉络丛中的离子通道多样性、通道表达及功能
Ian D Millar,Jason Ie Bruce,Peter D Brown
Ian D Millar
Knowledge of the diversity of ion channel form and function has increased enormously over the last 25 years. The initial impetus in channel discovery came with the introduction of the patch clamp method in 1981. Functional data from patch c...
Extrapyramidal signs in normal pressure hydrocephalus: an objective assessment [0.03%]
正常压力性脑积水的锥体外系体征：客观评估
Allen S Mandir,Jennifer Hilfiker,George Thomas et al.
Allen S Mandir et al.
Background: Beyond the classic Normal Pressure Hydrocephalus (NPH) triad of gait disturbance, incontinence, and dementia are characteristic signs of motor dysfunction in NPH patients. We used highly sensitive and objectiv...
Human arachnoid granulations Part I: a technique for quantifying area and distribution on the superior surface of the cerebral cortex [0.03%]
人脑蛛网膜颗粒Ⅰ：一种定量分析大脑皮层上方蛛网膜颗粒面积和分布的技术
Deborah M Grzybowski,Edward E Herderick,Kapil G Kapoor et al.
Deborah M Grzybowski et al.
Background: The arachnoid granulations (AGs) are herniations of the arachnoid membrane into the dural venous sinuses on the surface of the brain. Previous morphological studies of AGs have been limited in scope and only o...
Reduction of astrogliosis and microgliosis by cerebrospinal fluid shunting in experimental hydrocephalus [0.03%]
实验性脑积水中脑脊液分流减少星形胶质细胞和小胶质细胞增生
Janet M Miller,James P McAllister nd
Janet M Miller
Background: Reactive gliosis has the potential to alter biomechanical properties of the brain, impede neuronal regeneration and affect plasticity. Determining the onset and progression of reactive astrogliosis and microgl...
Conrad Johanson
Conrad Johanson
A report of a meeting sponsored by the BrainChild Foundation on the challenges for hydrocephalus researchers to provide the information required for better management of cerebrospinal fluid disorders.
Possible role of the cavernous sinus veins in cerebrospinal fluid absorption [0.03%]
海绵窦静脉在脑脊液吸收中的可能作用
Miles Johnston,Dianna Armstrong,Lena Koh
Miles Johnston
The purpose of this investigation was to enhance our understanding of cerebrospinal fluid (CSF) absorption pathways. To achieve this, Microfil (a coloured silastic material) was infused into the subarachnoid space (cisterna magna) of sheep ...