In normal rat, intraventricularly administered insulin-like growth factor-1 is rapidly cleared from CSF with limited distribution into brain [0.03%]
正常大鼠脑室内注射的胰岛素样生长因子-1快速清除出脑脊液并限局分布于脑内
Tavarekere N Nagaraja,Padma Patel,Martin Gorski et al.
Tavarekere N Nagaraja et al.
Background: Putatively active drugs are often intraventricularly administered to gain direct access to brain and circumvent the blood-brain barrier. A few studies on the normal central nervous system (CNS) have shown, how...
Hazel C Jones
Hazel C Jones
Article processing charges (APCs) have recently been introduced for authors submitting papers to Cerebrospinal Fluid Research. This editorial is to inform readers about the need and use of APCs and about the advantages of free open access p...
Expansion of antibody reactivity in the cerebrospinal fluid of multiple sclerosis patients - follow-up and clinical implications [0.03%]
多发性硬化患者的脑脊液中抗体反应性的扩大-随访及临床意义
Hela-Felicitas Petereit,Dirk Reske
Hela-Felicitas Petereit
Background: An intrathecal polyspecific antibody response is a well known finding in multiple sclerosis. However, little is known about the evolution of intrathecal antibodies over time and their impact on the disease pro...
Genetic loci for ventricular dilatation in the LEW/Jms rat with fetal-onset hydrocephalus are influenced by gender and genetic background [0.03%]
影响LEW/Jms胎生型脑积水大鼠心室扩大的遗传位点受性别和遗传背景的影响
Hazel C Jones,Crystal F Totten,David A Mayorga et al.
Hazel C Jones et al.
Background: The LEW/Jms rat strain has inherited hydrocephalus, with more males affected than females and an overall expression rate of 28%. This study aimed to determine chromosomal positions for genetic loci causing the...
48th Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida. Dublin, Ireland, 23-26 June 2004. Abstracts [0.03%]
第48届脑积水与脊柱裂学会年会论文摘要集（爱尔兰都柏林，2004年6月23日-26日）
C Sprung,C Miethke,M Brock
C Sprung
Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species [0.03%]
人类、非人灵长类及其他哺乳动物脑脊液与鼻淋巴管联系的证据
Miles Johnston,Andrei Zakharov,Christina Papaiconomou et al.
Miles Johnston et al.
BACKGROUND: The parenchyma of the brain does not contain lymphatics. Consequently, it has been assumed that arachnoid projections into the cranial venous system are responsible for cerebrospinal fluid (CSF) absorption. However, recent quant...
Homeostatic capabilities of the choroid plexus epithelium in Alzheimer's disease [0.03%]
阿尔茨海默病中脉络丛上皮的稳态功能
Conrad Johanson,Paul McMillan,Rosemarie Tavares et al.
Conrad Johanson et al.
As the secretory source of vitamins, peptides and hormones for neurons, the choroid plexus (CP) epithelium critically provides substances for brain homeostasis. This distributive process of cerebrospinal fluid (CSF) volume transmission reac...
Behroze Vachha,Richard C Adams
Behroze Vachha
: This article was the winner of the triennial Casey Holter Memorial Prize awarded by the Society for Research into Hydrocephalus and Spina Bifida, 2004. ABSTRACT: This essay explores the link between the limbic/hypothalamic systems within ...
David B Shurtleff
David B Shurtleff
This review article combines four disparate observations about Neural Tube Defects (NTDs). They are the worldwide decline in the birth incidence that began prior to prenatal diagnosis; family recurrence risks; the effect of prenatal diagnos...
Lifestyle in adults aged 35 years who were born with open spina bifida: prospective cohort study [0.03%]
一项前瞻性队列研究：35岁先天性脊柱裂成人患者的生活方式状况
Gillian M Hunt,Pippa Oakeshott
Gillian M Hunt
BACKGROUND AND METHODS: From 1963 to 1971, 117 babies with open spina bifida were treated non-selectively from birth. In 2002 we reviewed all the survivors by postal questionnaire and telephone call. The aims were to find out how many were ...