Adiposity measures and vitamin D concentrations in Northeast Germany and Denmark [0.03%]
德国东北部和丹麦的肥胖指标与维生素D浓度的关系
A Hannemann,B Heinsbaek Thuesen,N Friedrich et al.
A Hannemann et al.
Background: Body mass index (BMI) and serum 25-hydroxy vitamin D3 (25OHD) concentrations are inversely related. As BMI contains only limited information regarding body fat distribution, we aimed to analyze the cross-secti...
Ammonia-lowering activities and carbamoyl phosphate synthetase 1 (Cps1) induction mechanism of a natural flavonoid [0.03%]
一种天然黄酮降低血氨和诱导尿素循环酶CPS1的机制研究
Kazunari Nohara,Youngmin Shin,Noheon Park et al.
Kazunari Nohara et al.
Objective: Ammonia detoxification is essential for physiological well-being, and the urea cycle in liver plays a predominant role in ammonia disposal. Nobiletin (NOB), a natural dietary flavonoid, is known to exhibit vari...
Adherence to hunger training using blood glucose monitoring: a feasibility study [0.03%]
基于血糖监测的饥饿训练依从性可行性研究
M R Jospe,R C Brown,M Roy et al.
M R Jospe et al.
Background: "Hunger training", which aims to teach people to eat only when blood glucose is below a set target, appears promising as a weight loss strategy. As the ability of participants to adhere to the rigorous protoco...
Decreased secretion of adiponectin through its intracellular accumulation in adipose tissue during tobacco smoke exposure [0.03%]
烟草烟雾暴露通过促进脂肪组织内脂联素蓄积而减少其分泌
Mingzhen Li,Chunjun Li,Yu Liu et al.
Mingzhen Li et al.
Background: Cigarette smoking is associated with an increased risk of type 2 diabetes mellitus (T2DM). Smokers exhibit low circulating levels of total adiponectin (ADPN) and high-molecular-weight (HMW) ADPN multimers. Blo...
Inflamed macrophage microvesicles induce insulin resistance in human adipocytes [0.03%]
炎症巨噬细胞微囊在人体脂肪细胞中诱发胰岛素抵抗现象
Yaqin Zhang,Li Shi,Hongliang Mei et al.
Yaqin Zhang et al.
Background: Cytokines secreted by adipose tissue macrophages (ATMs) significantly alter adipocyte function, inducing inflammatory responses and decreasing insulin sensitivity. However, little relevant information is avail...
A novel anti-inflammatory natural product from Sphaeranthus indicus inhibits expression of VCAM1 and ICAM1, and slows atherosclerosis progression independent of lipid changes [0.03%]
来自Sphaeranthus indicus的新型抗炎天然产物抑制VCAM1和ICAM1的表达,并且独立于血脂变化减慢动脉粥样硬化进程
Rai Ajit K Srivastava,Sapna Mistry,Somesh Sharma
Rai Ajit K Srivastava
A large body of evidence suggests that atherosclerosis is an inflammatory disease, in which cytokines and growth factors play a major role in disease progression. The methanolic extracts of Sphaeranthus indicus as well as its active ingredi...
E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish [0.03%]
E2F8通过在斑马鱼饮食引起的肥胖中促进FABP3的表达来促进肝脏脂肪变性
Yasuhito Shimada,Shisei Kuninaga,Michiko Ariyoshi et al.
Yasuhito Shimada et al.
Background: Diet-induced hepatic steatosis is highly associated with nonalcoholic fatty liver disease, which is related to the development of metabolic syndrome. While advanced stage nonalcoholic hepatic steatosis and ste...
Chlorogenic acid/chromium supplement rescues diet-induced insulin resistance and obesity in mice [0.03%]
氯ogenic酸/铬补充剂可救治饮食引起的胰岛素抵抗和肥胖(在小鼠中)
Hilda E Ghadieh,Zachary N Smiley,Melissa W Kopfman et al.
Hilda E Ghadieh et al.
Abdominal obesity is a major risk factor for insulin resistance, type 2 diabetes and cardiovascular diseases. Dietary fat induces insulin resistance in humans and rodents. The current study investigates whether a Chlorogenic acid/Chromium I...
Beneficial effects of inorganic nitrate/nitrite in type 2 diabetes and its complications [0.03%]
无机硝酸盐/亚硝酸盐对二型糖尿病及其并发症的益处效果
Zahra Bahadoran,Asghar Ghasemi,Parvin Mirmiran et al.
Zahra Bahadoran et al.
Background and aim: The ability of inorganic nitrate and nitrite to convert to nitric oxide (NO), and some of its properties e.g. regulation of glucose metabolism, vascular homeostasis, and insulin signaling pathway, have...
Sailas Benjamin,Priji Prakasan,Sajith Sreedharan et al.
Sailas Benjamin et al.
This comprehensive review critically evaluates whether supposed health benefits propounded upon human consumption of conjugated linoleic acids (CLAs) are clinically proven or not. With a general introduction on the chemistry of CLA, major c...