Compared to casein, bovine lactoferrin reduces plasma leptin and corticosterone and affects hypothalamic gene expression without altering weight gain or fat mass in high fat diet fed C57/BL6J mice [0.03%]
与酪蛋白相比，牛乳铁蛋白可减少高脂饮食喂养的C57/BL6J小鼠血浆瘦素和皮质酮水平并影响下丘脑基因表达且不影响体重增加或脂肪量
Bettina McManus,Riitta Korpela,Paula O&#x;Connor et al.
Bettina McManus et al.
Background: Several studies in both humans and rodents have examined the use of lactoferrin as a dietary solution to weight gain and visceral fat accretion and have shown promising results in the short term (up to 7 weeks...
Combined intervention with pioglitazone and n-3 fatty acids in metformin-treated type 2 diabetic patients: improvement of lipid metabolism [0.03%]
二甲双胍治疗的2型糖尿病患者加用吡格列酮和n-3不饱和脂肪酸联合干预：改善脂代谢
Jiri Veleba,Jan Kopecky Jr,Petra Janovska et al.
Jiri Veleba et al.
Background: The marine n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) exert numerous beneficial effects on health, but their potency to improve treatment of type 2 diabetic (T2D) patients rema...
Satoru Sugimoto,Hisakazu Nakajima,Kitaro Kosaka et al.
Satoru Sugimoto et al.
The number of obese patients has increased annually worldwide. Therefore, there is a strong need to develop a new effective and safe anti-obesity drug. Miglitol is an alpha-glucosidase inhibitor (αGI) that is commonly used as an anti-diabe...
Higher visceral fat area increases the risk of vitamin D insufficiency and deficiency in Chinese adults [0.03%]
更高的内脏脂肪面积会增加中国成年人维生素D不足和缺乏的风险
Meilin Zhang,Ping Li,Yufeng Zhu et al.
Meilin Zhang et al.
Background: Visceral fat area (VFA), a novel sex-specific index for visceral fat obesity (VFO) might play a major role in the development of vitamin D deficiency. However, the association between VFA and vitamin D insuffi...
Simona Granata,Alessandra Dalla Gassa,Paola Tomei et al.
Simona Granata et al.
Cellular metabolic changes during chronic kidney disease (CKD) may induce higher production of oxygen radicals that play a significant role in the progression of renal damage and in the onset of important comorbidities. This condition seems...
Xianqin Zhang,Toshifumi Osaka,Satoshi Tsuneda
Xianqin Zhang
Background: The farnesoid X receptor (FXR), a ligand-activated transcription factor belonging to the adopted orphan receptor, plays an important role in maintaining health of the liver and intestine. In this study, we ide...
Longitudinal study on the association between three dietary indices, anthropometric parameters and blood lipids [0.03%]
三种膳食指数与生化、体格指标的纵向关系研究
Evelien Mertens,Benedicte Deforche,Patrick Mullie et al.
Evelien Mertens et al.
Background: From a health promotion perspective, the use of dietary indices is preferred above single nutrients and foods to evaluate diet quality. Longitudinal research about the association between dietary indices and r...
Evaluation of a new whole room indirect calorimeter specific for measurement of resting metabolic rate [0.03%]
新型全身间室间接量热计测定基础代谢率的价值评估研究
Russell Rising,Kathryn Whyte,Jeanine Albu et al.
Russell Rising et al.
Background: The most common methods for obtaining human resting metabolic rate (RMR) use either a ventilated hood connected to a metabolic cart (VH_MC) or calculation by many prediction equations utilizing the person's he...
Influence of obesity on vertebral fracture prevalence and vitamin D status in postmenopausal women [0.03%]
肥胖对绝经后妇女椎体骨折患病率和维生素D状况的影响
A El Maghraoui,S Sadni,A El Maataoui et al.
A El Maghraoui et al.
Background: It is well established that weight is an important determinant of bone health. Whereas obesity is associated with increased mortality and morbidity from diabetes and cardiovascular diseases, high body weight i...
High fat plus high cholesterol diet lead to hepatic steatosis in zebrafish larvae: a novel model for screening anti-hepatic steatosis drugs [0.03%]
高脂肪及高胆固醇饮食导致斑马鱼肝脂质沉积：一种新型抗肝脂质沉积药物筛选模型
Wencong Dai,Kunyuan Wang,Xinchun Zheng et al.
Wencong Dai et al.
Background: Non-alcoholic fatty liver disease (NAFLD), characterized as excessive lipid accumulation within hepatocytes, is growing in prevalence. The exploitation of effective drugs for NAFLD has been proven challenging....