Argininemia and plasma arginine bioavailability - predictive factors of mortality in the severe trauma patients? [0.03%]
瓜氨酸血症与血浆精氨酸生物利用度对重度创伤患者病死率的预测价值？
Beatriz P Costa,Paulo Martins,Carla Veríssimo et al.
Beatriz P Costa et al.
Background: Arginine is an amino acid determinant in the metabolic, immune and reparative responses to severe trauma. The present study aims to determine argininemia and plasma arginine bioavailability (PAB) in critical t...
Fatty acids stimulate insulin secretion from human pancreatic islets at fasting glucose concentrations via mitochondria-dependent and -independent mechanisms [0.03%]
脂肪酸通过线粒体依赖性和非依赖性机制刺激人胰岛细胞在空腹血糖浓度下的胰岛素分泌
Jing Cen,Ernest Sargsyan,Peter Bergsten
Jing Cen
Background: Free fatty acids (FFAs) acutely stimulate insulin secretion from pancreatic islets. Conflicting results have been presented regarding this effect at non-stimulatory glucose concentration, however. The aim of o...
Effects of dietary fat subtypes on glucose homeostasis during pregnancy in rats [0.03%]
孕期母鼠膳食脂肪酸类型对糖代谢的影响
Len H Storlien,Yan Y Lam,Ben J Wu et al.
Len H Storlien et al.
Background: Dietary n-3 and n-6 polyunsaturated fatty acids (PUFAs) have an impact on insulin secretion and sensitivity but whether and how these may be related to maternal glucose homeostasis during pregnancy is unclear....
Prolonged transfer of feces from the lean mice modulates gut microbiota in obese mice [0.03%]
取自瘦小鼠的粪菌移植可以长时间调节肥胖小鼠的肠道微生物群
Maria Kulecka,Agnieszka Paziewska,Natalia Zeber-Lubecka et al.
Maria Kulecka et al.
Background: Transplanting a fecal sample from lean, healthy donors to obese recipients has been shown to improve metabolic syndrome symptoms. We therefore examined the gut microbiota in mice after administering a long-ter...
The effect of inhibiting glycinamide ribonucleotide formyl transferase on the development of neural tube in mice [0.03%]
糖氨乳清核苷酸甲酰基转移酶抑制对小鼠神经管发育的影响研究
Lin Xu,Li Wang,JianHua Wang et al.
Lin Xu et al.
Background: Folate deficiency is closely related to the development of neural tube defects (NTDs). However, the exact mechanism is not completely understood. This study aims to induce murine NTDs by inhibiting one of the ...
The effects of prenatal metformin on obesogenic diet-induced alterations in maternal and fetal fatty acid metabolism [0.03%]
孕前美formin对肥胖饮食诱导的母体和胎儿脂肪酸代谢异常的影响
Kemoy Harris,Neeraj Desai,Madhu Gupta et al.
Kemoy Harris et al.
Background: Maternal obesity may program the fetus and increase the susceptibility of the offspring to adult diseases. Metformin crosses the placenta and has been associated with decreased inflammation and reversal of fat...
2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer [0.03%]
2氨基-1甲基-6苯基咪唑并吡啶（PhIP）可诱导与炎症，糖尿病和癌症相关的JAK/STAT和MAPK通路的基因表达变化
Lora J Rogers,Alexei G Basnakian,Mohammed S Orloff et al.
Lora J Rogers et al.
Background: 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP), a heterocyclic aromatic amine (HCA) formed in meat that is cooked at high temperatures and then ingested, can potentially be retained in human adipose ti...
Assessment of Vitamin D status in a group of Egyptian children with non alcoholic fatty liver disease (multicenter study) [0.03%]
评估一组埃及非酒精性脂肪肝病儿童的维生素D状况（多中心研究）
Amal Mohamed Ahmed,Maha Abdel Ghany,Gehan Lotfy Abdel Hakeem et al.
Amal Mohamed Ahmed et al.
Background: Nonalcoholic fatty liver disease (NAFLD) is one of the health problems with great burden on the liver that may end with liver cirrhosis and hepatocellular carcinoma. The aim of this work was to assess serum vi...
Modified Atkins diet in advanced malignancies - final results of a safety and feasibility trial within the Veterans Affairs Pittsburgh Healthcare System [0.03%]
Modified Atkins饮食在晚期恶性肿瘤中的应用-退伍军人事务部门匹兹堡医疗系统的安全性和可行性试验最终结果
Jocelyn L Tan-Shalaby,Jennifer Carrick,Krystal Edinger et al.
Jocelyn L Tan-Shalaby et al.
Background: Dysfunctional mitochondrial processes limit malignant cells ability to use energy from fatty acids and ketones. Animal studies using ketogenic diets for cancer show encouraging results. We tested the diet's sa...
High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs [0.03%]
高脂肪而非蔗糖摄入是 Guinea 猪诱导血脂异常和非酒精性steatohepatitis的必要条件
David Højland Ipsen,Pernille Tveden-Nyborg,Bidda Rolin et al.
David Højland Ipsen et al.
Background: Non-alcoholic fatty liver disease (NAFLD) and dyslipidemia are closely related. Diet plays an important role in the progression of these diseases, but the role of specific dietary components is not completely ...