Press-pulse: a novel therapeutic strategy for the metabolic management of cancer [0.03%]
压脉疗法：癌症代谢管理的新策略
Thomas N Seyfried,George Yu,Joseph C Maroon et al.
Thomas N Seyfried et al.
Background: A shift from respiration to fermentation is a common metabolic hallmark of cancer cells. As a result, glucose and glutamine become the prime fuels for driving the dysregulated growth of tumors. The simultaneou...
Long-term intake of saccharin decreases post-absortive energy expenditure at rest and is associated to greater weight gain relative to sucrose in wistar rats [0.03%]
安替甜长期摄入降低大鼠非进食状态下静息能量消耗并较蔗糖处理导致更高的体重增加效应
Denise Entrudo Pinto,Kelly Carraro Foletto,Ramiro Barcos Nunes et al.
Denise Entrudo Pinto et al.
Background: Non-nutritive sweeteners (NNS) have been associated with increased prevalence of obesity. In previous studies, we demonstrated that saccharin could induce an increase in weight gain either when compared to suc...
Impact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adults [0.03%]
为期6周的非能量限制生酮饮食对健康成年人身体健康、体成分和生化指标的影响研究
Paul Urbain,Lena Strom,Lena Morawski et al.
Paul Urbain et al.
Background: The ketogenic diet (KD) is a very low-carbohydrate, high-fat and adequate-protein diet that without limiting calories induces different metabolic adaptations, eg, increased levels of circulating ketone bodies ...
Lipid overload during gestation and lactation can independently alter lipid homeostasis in offspring and promote metabolic impairment after new challenge to high-fat diet [0.03%]
妊娠和哺乳期间脂质过载可以独立改变后代脂质稳态并促进高脂肪饮食新挑战后的代谢障碍
Laís Angélica de Paula Simino,Thaís de Fante,Marina Figueiredo Fontana et al.
Laís Angélica de Paula Simino et al.
Background: Nutritional status in early life is critically involved in the metabolic phenotype of offspring. However the changes triggered by maternal consumption of high-fat diet (HFD) in pre- or postnatal period should ...
Lidiya G Dimova,Nikola Zlatkov,Henkjan J Verkade et al.
Lidiya G Dimova et al.
Introduction: Western diet containing both saturated fat and cholesterol impairs cardio-metabolic health partly by modulating diversity and function of the microbiota. While diet containing only high fat has comparable ef...
Hepatic iron storage is related to body adiposity and hepatic inflammation [0.03%]
肝脏铁储存与机体脂肪沉积和肝炎相关
Chan Yoon Park,Jayong Chung,Kyung-Ok Koo et al.
Chan Yoon Park et al.
Background: Obesity has been reported to be associated with iron deficiency. However, few studies have investigated iron status in low adiposity. To investigate whether body adiposity was associated with altered hepatic i...
Supplementation with dairy calcium and/or flaxseed fibers in conjunction with orlistat augments fecal fat excretion without altering ratings of gastrointestinal comfort [0.03%]
补充乳钙和/或亚麻籽纤维与奥利司他联用可增加粪便脂肪的排泄量而不改变胃肠道舒适度评分
Mette Kristensen,Signe Rømer Juul,Karina Vejrum Sørensen et al.
Mette Kristensen et al.
Background: Orlistat is a lipase inhibitor which reduced absorption of dietary fat by ~30% thereby inducing a weight loss; however, side effects occur as a consequence of increased colonic fat content. To test the hypothe...
Phosphatidic acid: biosynthesis, pharmacokinetics, mechanisms of action and effect on strength and body composition in resistance-trained individuals [0.03%]
磷脂酸：生物合成、药代动力学、作用机制及其对抗阻训练人群肌肉力量和身体组成的影响
Peter Bond
Peter Bond
The mechanistic target of rapamycin complex 1 (mTORC1) has received much attention in the field of exercise physiology as a master regulator of skeletal muscle hypertrophy. The multiprotein complex is regulated by various signals such as gr...
Weight loss technology for people with treated type 2 diabetes: a randomized controlled trial [0.03%]
接受治疗的2型糖尿病患者的减重疗法：一项随机对照试验
Kuat Oshakbayev,Bibazhar Dukenbayeva,Gulnar Togizbayeva et al.
Kuat Oshakbayev et al.
Background: The prevalence of type 2 diabetes is increasing in worldwide despite the development of new treatment methods. Aim of the study was to evaluate a weight loss method on body composition, glycemic, lipid and hor...
Dietary supplementation with bovine-derived milk fat globule membrane lipids promotes neuromuscular development in growing rats [0.03%]
牛源乳脂肪球膜脂质膳食补充促进大鼠生长期间的神经肌肉发育
James F Markworth,Brenan Durainayagam,Vandre C Figueiredo et al.
James F Markworth et al.
Background: The milk fat globule membrane (MFGM) is primarily composed of polar phospho- and sphingolipids, which have established biological effects on neuroplasticity. The present study aimed to investigate the effect o...