Protective effects of γ-aminobutyric acid against H2O2-induced oxidative stress in RIN-m5F pancreatic cells [0.03%]
γ-氨基丁酸对抗H2O2诱导的RIN-m5F胰腺细胞氧化应激的保护作用
Xue Tang,Renqiang Yu,Qin Zhou et al.
Xue Tang et al.
Background: γ-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter in the central nervous system and reported to maintain the redox homeostasis and insulin secretion function of pancreatic β cells. This study...
PPARγ/Pgc-1α-Fndc5 pathway up-regulation in gastrocnemius and heart muscle of exercised, branched chain amino acid diet fed mice [0.03%]
运动及支链氨基酸喂养上调小鼠腓肠肌和心脏组织中PPARγ/Pgc-1α-Fndc5通路
Navid Abedpoor,Farzaneh Taghian,Kamran Ghaedi et al.
Navid Abedpoor et al.
Background: Previous studies have revealed the inductive effect of branched-chain amino acids (BCAAs) catabolism on fatty acid oxidation and metabolism, especially in muscle cells. In the present investigation, we have at...
Dietary vitamin D3 supplementation protects laying hens against lipopolysaccharide-induced immunological stress [0.03%]
维生素D3膳食补充可以保护产蛋鸡抵抗脂多糖诱导的免疫学应激反应
Yanqiang Geng,Qiugang Ma,Zhong Wang et al.
Yanqiang Geng et al.
Background: The effects of vitamin D on the immune function of laying hens are not well understood. This study investigated the effects of vitamin D3 (VD3) on laying performance and immunological functions in laying hens ...
Metabolomic profiles associated with bone mineral density in US Caucasian women [0.03%]
与美国白人女性骨密度相关的代谢组学特征
Qi Zhao,Hui Shen,Kuan-Jui Su et al.
Qi Zhao et al.
Background: Individuals' peak bone mineral density (BMD) achieved and maintained at ages 20-40 years is the most powerful predictor of low bone mass and osteoporotic fractures later in life. The aim of this study was to i...
Vitamin D supplementation and serum heat shock protein 60 levels in patients with coronary heart disease: a randomized clinical trial [0.03%]
维生素D补充剂对冠心病患者血清热休克蛋白60水平的影响：一项随机临床试验
Leila Sadat Bahrami,Seyed Hashem Sezavar Seyedi Jandaghi,Leila Janani et al.
Leila Sadat Bahrami et al.
Background: The aim in this study was to investigate the effect of vitamin D (25(OH)D3) supplementation on heat shock protein 60 (HSP 60) and other inflammatory markers (IL-17, TNF-α, PAB) in patients with coronary heart...
Switching from a high-fat cellulose diet to a high-fat pectin diet reverses certain obesity-related morbidities [0.03%]
从高脂肪纤维素饮食转换到高脂肪果胶饮食可逆转某些与肥胖相关的并发症
Julie K Bray,Gabriel S Chiu,Leslie K McNeil et al.
Julie K Bray et al.
Background: Reducing caloric intake is a proven intervention for mitigating and modulating morbidities associated with overnutrition. Caloric restriction is difficult to affect clinically, therefore, dietary interventions...
Long-term high-protein diet intake reverts weight gain and attenuates metabolic dysfunction on high-sucrose-fed adult rats [0.03%]
长期高蛋白饮食可逆转高果糖诱导的成年大鼠体重增加并改善代谢异常
Rosângela Maria Lopes Sousa,Nathalee Liberal Xavier Ribeiro,Bruno Araújo Serra Pinto et al.
Rosângela Maria Lopes Sousa et al.
Background: Consumption of added sugars has been considered a worldwide public health concern by its association with metabolic syndrome and its comorbidities. Meanwhile, current studies have suggested high-protein diets ...
PPARG2 Pro12Ala polymorphism influences body composition changes in severely obese patients consuming extra virgin olive oil: a randomized clinical trial [0.03%]
一项随机临床试验：严重肥胖患者食用特级初榨橄榄油时PPARG2 Pro12Ala多态性影响体成分变化
Ana Paula Santos Rodrigues,Lorena Pereira Souza Rosa,Erika Aparecida Silveira
Ana Paula Santos Rodrigues
Background: Previous intervention studies have reported the association of the PPARG2 Pro12Ala (rs1801282) and IL6 -174G > C (rs1800795) polymorphisms with weight loss; however, their results are inconsistent. We aimed to...
Changes in lysophospholipids and liver status after weight loss: the RESMENA study [0.03%]
RESMENA研究中体重减轻后肝脂肪和溶血磷脂的变化趋势
Irene Cantero,Itziar Abete,Josep Maria Del Bas et al.
Irene Cantero et al.
Background: Obesity and comorbidities such as non-alcoholic fatty liver disease (NAFLD) are major public health burdens. Alterations in lipid metabolism are involved in hepatic diseases. The objective of this study was to...
Impact of 3-year changes in lipid parameters and their ratios on incident type 2 diabetes: Tehran lipid and glucose study [0.03%]
Tehran Lipid and Glucose Study中血脂参数及比值3年变化对2型糖尿病发病的影响
Pegah Khaloo,Mitra Hasheminia,Maryam Tohidi et al.
Pegah Khaloo et al.
Background: To examine the impact of changes in all lipid measures including total cholesterol (TC), log-transformed triglycerides (Ln-TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol...