ANGPTL4 variants and their haplotypes are associated with serum lipid levels, the risk of coronary artery disease and ischemic stroke and atorvastatin cholesterol-lowering responses [0.03%]
血管生成素样蛋白4变异及其单体型与血脂水平、冠心病和缺血性脑卒中的发病风险以及阿托伐他汀降脂疗效的关系
Qian Yang,Rui-Xing Yin,Xiao-Li Cao et al.
Qian Yang et al.
Background: This study aimed to assess the association between the angiopoietin-like protein 4 gene (ANGPTL4) single nucleotide polymorphisms (SNPs) and serum lipid levels, the risk of coronary artery disease (CAD) and is...
Effect of personalized moderate exercise training on Wistar rats fed with a fructose enriched water [0.03%]
个性化中等强度运动对富果糖饮水喂养Wistar大鼠的影响
Julie Dupas,Annie Feray,Anthony Guernec et al.
Julie Dupas et al.
Background: Metabolic Syndrom has become a public health problem. It mainly results from the increased consumption of fat and sugar. In this context, the benefits of personalized moderate exercise training were investigat...
MicroRNAs from plants to animals, do they define a new messenger for communication? [0.03%]
从植物到动物的微小RNA，它们是新的信号传递分子吗？
Zhiqing Li,Ruodan Xu,Ning Li
Zhiqing Li
MicroRNAs (miRNAs), a class of single-stranded non-coding RNA of about 22 nucleotides, are potent regulators of gene expression existing in both plants and animals. Recent studies showed that plant miRNAs could enter mammalian bloodstream v...
Effects of exenatide versus insulin glargine on body composition in overweight and obese T2DM patients: a randomized controlled trial [0.03%]
艾塞那肽与甘精胰岛素对超重和肥胖2型糖尿病患者身体组成影响的随机对照试验
Ting-Ting Yin,Yan Bi,Ping Li et al.
Ting-Ting Yin et al.
Background: Weight loss, especially fat mass reduction, helps to improve blood glucose control, insulin sensitivity, and β-cell function. This study aimed to compare the effect of exenatide and glargine on body compositi...
Alpha-lipoic acid preserves skeletal muscle mass in type 2 diabetic OLETF rats [0.03%]
α-型乙酰辅酶A保护2型糖尿病OLETF大鼠的骨骼肌质量
Oak-Kee Hong,Jang-Won Son,Hyuk-Sang Kwon et al.
Oak-Kee Hong et al.
Background: Increased oxidative stress and impaired antioxidant defense are important mechanisms in the pathogenesis of diabetic myopathy. Alpha-lipoic acid (ALA) has been indicated as a weight-loss treatment in rodents a...
Dietary n-3 long-chain polyunsaturated fatty acids upregulate energy dissipating metabolic pathways conveying anti-obesogenic effects in mice [0.03%]
膳食n-3长链多不饱和脂肪酸通过上调能量耗散代谢途径发挥抗肥胖作用
Stefanie Worsch,Mathias Heikenwalder,Hans Hauner et al.
Stefanie Worsch et al.
Background: We previously reported on the anti-obesogenic and anti-inflammatory effects associated with n-3 long-chain polyunsaturated fatty acids (LCPUFA) in our diet-induced obesity (DIO) mouse model. Two isocaloric hig...
Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity [0.03%]
从高脂、果糖和胆固醇饮食转换到普通饲料可限制肥胖戈特инг根小猪模型心肌胶原的量
Laura Jul Andreasen,Simone Krog,Trine Pagh Ludvigsen et al.
Laura Jul Andreasen et al.
Background: Dietary interventions have been shown to attenuate some of the myocardial pathological alterations associated with obesity. This study evaluated the effect of dietary normalization from a fat/fructose/choleste...
Green cardamom increases Sirtuin-1 and reduces inflammation in overweight or obese patients with non-alcoholic fatty liver disease: a double-blind randomized placebo-controlled clinical trial [0.03%]
绿豆蔻素体试验：姜黄素通过上调Sirtuin-1和下调炎症因子抑制非酒精性脂肪肝病患者肝脏甘油三酯的合成
Milad Daneshi-Maskooni,Seyed Ali Keshavarz,Mostafa Qorbani et al.
Milad Daneshi-Maskooni et al.
Background: Non-alcoholic fatty liver disease (NAFLD) is the hepatic component of metabolic syndrome. Despite the beneficial health effects of cardamom on dyslipidemia, hepatomegaly, and fasting hyperglycemia, no previous...
Whole-body net protein balance plateaus in response to increasing protein intakes during post-exercise recovery in adults and adolescents [0.03%]
成人和青少年运动后的恢复期间全身蛋白质平衡在摄入增加的蛋白后达到饱和状态
Michael Mazzulla,Kimberly A Volterman,Jeff E Packer et al.
Michael Mazzulla et al.
Background: Muscle protein synthesis and muscle net balance plateau after moderate protein ingestion in adults. However, it has been suggested that there is no practical limit to the anabolic response of whole-body net ba...
Consumption of regular-fat vs reduced-fat cheese reveals gender-specific changes in LDL particle size - a randomized controlled trial [0.03%]
全脂奶酪和低脂奶酪的摄入对LDL颗粒大小影响的随机对照试验：因性别而异
Farinaz Raziani,Parvaneh Ebrahimi,Søren Balling Engelsen et al.
Farinaz Raziani et al.
Background: Regular-fat cheese does not seem to increase low density lipoprotein cholesterol (LDL-C) concentrations compared to reduced-fat cheese. However, plasma LDL-C concentrations do not reflect levels and size of LD...