Metabolic effects of mulberry branch bark powder on diabetic mice based on GC-MS metabolomics approach [0.03%]
基于GC-MS代谢组学方法研究桑寄白皮对糖尿病小鼠的代谢影响
Fan Qiu,Yu-Qing Zhang
Fan Qiu
Background: Mulberry (Morus multicaulis) branch bark powder have showed effective hypoglycemic activity in our previous research. This study aims to explore the mechanism of protect effect on diabetes mice of mulberry bra...
Resveratrol attenuates oxidative injury in human umbilical vein endothelial cells through regulating mitochondrial fusion via TyrRS-PARP1 pathway [0.03%]
白藜芦醇通过调节酪氨酰-tRNA合成酶-聚（ADP-核糖）聚合酶1信号通路调控线粒体融合从而减轻人脐静脉内皮细胞氧化损伤
Jining Yang,Xi Zhou,Xianglong Zeng et al.
Jining Yang et al.
Background/aims: Oxidative stress-induced damage in endothelial cells is a crucial initiator of atherosclerosis (AS), which is highly related to excessive reactive oxygen species (ROS) and mitochondrial dynamics. Resverat...
Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease (NAFLD): a double-blind randomized placebo-controlled clinical trial [0.03%]
纳米姜黄素改善非酒精性脂肪肝病（NAFLD）患者的超重和肥胖相关的血糖指数，血脂，炎症和Nesfatin：一项双盲随机安慰剂对照临床试验
Seyed Ali Jazayeri-Tehrani,Seyed Mahdi Rezayat,Siavash Mansouri et al.
Seyed Ali Jazayeri-Tehrani et al.
Background: Since lifestyle changes are main therapies for non-alcoholic fatty liver disease (NAFLD), changing dietary components (nutritional or bioactive) may play a parallel important role. Few studies have assessed th...
Small dense LDL cholesterol is associated with metabolic syndrome traits independently of obesity and inflammation [0.03%]
小而密低密度脂蛋白胆固醇与肥胖和炎症相独立的代谢综合征指标相关性研究
Jiahua Fan,Yangqing Liu,Songping Yin et al.
Jiahua Fan et al.
Background: Small dense LDL cholesterol (sdLDL-c) has been established to be highly associated with metabolic disorder. However, the relationship between circulating sdLDL-c and the presence of metabolic syndrome (MetS) h...
Dietary supplement of Smilax china L. ethanol extract alleviates the lipid accumulation by activating AMPK pathways in high-fat diet fed mice [0.03%]
中国菝葜乙醇提取物膳食补充通过激活AMPK途径缓解高脂饮食小鼠的脂质蓄积
Licong Yang,Yan Zhao,Yongfang Pan et al.
Licong Yang et al.
Background: Obesity has become a public health concern worldwide because it is linked to numerous metabolic disorders, such as hyperlipidemia, hypertension and cardiovascular disease. Therefore, there is an urgent need to...
The GC2 haplotype of the vitamin D binding protein is a risk factor for a low plasma 25-hydroxyvitamin D concentration in a Han Chinese population [0.03%]
维生素D结合蛋白GC2等位基因是中国汉族人群血浆25-羟基维生素D浓度偏低的风险因素
Ji-Chang Zhou,Yumei Zhu,Chunmei Gong et al.
Ji-Chang Zhou et al.
Background: The GC haplotype of the vitamin D binding protein (encoded by the GC gene) might be a risk factor to the vitamin D (VD) nutritional status for many populations, while evidences from the Chinese Han population ...
Effect of the lipoxygenase inhibitor baicalein on bone tissue and bone healing in ovariectomized rats [0.03%]
黄芩素对卵巢切除大鼠骨组织及骨折愈合的影响
Dominik Saul,Marie Weber,Marc Hendrik Zimmermann et al.
Dominik Saul et al.
Background: Osteoporosis is one of the world's major medical burdens in the twenty-first century. Pharmaceutical intervention currently focusses on decelerating bone loss, but phytochemicals such as baicalein, which is a ...
Retinol binding protein 4 and risk of type 2 diabetes in Singapore Chinese men and women: a nested case-control study [0.03%]
维生素RBP4与新加坡华人2型糖尿病风险关系的病例对照研究
Yeli Wang,Liang Sun,Xu Lin et al.
Yeli Wang et al.
Background: Although retinol binding protein 4 (RBP4) has been implicated in insulin resistance in experimental studies, the association between RBP4 and risk of type 2 diabetes remains unclear. We assessed this associati...
Plasma acylcarnitines could predict prognosis and evaluate treatment of IgA nephropathy [0.03%]
血浆酰基肉毒碱可能用于预测IgA肾病预后及评估治疗效果
Fang-Ying Xia,Li Zhu,Chao Xu et al.
Fang-Ying Xia et al.
Background: Effective evaluation or prediction of therapy response could be helpful for treatment of chronic kidney disease (CKD), which may rely on accurate biomarkers. Acylcarnitines are involved with lipid metabolism a...
Maternal dietary ratio of linoleic acid to alpha-linolenic acid during pregnancy has sex-specific effects on placental and fetal weights in the rat [0.03%]
妊娠大鼠日粮中亚油酸与α-亚麻酸比例对胎盘及胎儿重量的性别特异性影响
Sally A V Draycott,Ge Liu,Zoe C Daniel et al.
Sally A V Draycott et al.
Background: Increased consumption of linoleic acid (LA, omega-6) in Western diets coupled with the pro-inflammatory and adipogenic properties of its derivatives has led to suggestions that fetal exposure to this dietary p...