Evidence for liver energy metabolism programming in offspring subjected to intrauterine undernutrition during midgestation [0.03%]
中孕期子宫内营养不良暴露编程子代肝能量代谢的表观遗传机制研究
Xiaoling Zhou,Hong Yang,Qiongxian Yan et al.
Xiaoling Zhou et al.
Background: Maternal undernutrition programs fetal energy homeostasis and increases the risk of metabolic disorders later in life. This study aimed to identify the signs of hepatic metabolic programming in utero and durin...
Maternal diet deficient in riboflavin induces embryonic death associated with alterations in the hepatic proteome of duck embryos [0.03%]
核黄素缺乏的母体饮食通过引起肝蛋白组改变而导致番鸭胚胎死亡
Jing Tang,Jian Hu,Ming Xue et al.
Jing Tang et al.
Background: Maternal riboflavin deficiency (RD) induces embryonic death in poultry. The underlying mechanisms, however, remain to be established and an overview of molecular alterations at the protein level is still lacki...
Effects of fermentable high fiber diet supplementation on gut derived and conventional nitrogenous product in patients on maintenance hemodialysis: a randomized controlled trial [0.03%]
发酵性高纤维饮食补充对维持性血液透析患者肠道来源及常规氮代谢产物的影响:一项随机对照试验
Hamid Tayebi Khosroshahi,Behzad Abedi,Morteza Ghojazadeh et al.
Hamid Tayebi Khosroshahi et al.
Introduction: Gut derived toxins such as p-cresol, p-cresyl sulfate (pCS) and indoxyl sulfate (IS), which belong to protein-bound uremic toxins that promote development of fibrosis inflammatory state associated with chron...
Aerobic exercise decreases chemerin/CMKLR1 in the serum and peripheral metabolic organs of obesity and diabetes rats by increasing PPARγ [0.03%]
有氧运动通过增加PPARγ降低肥胖糖尿病大鼠血清及外周代谢组织中chemerin/CMKLR1水平
Xiaojing Lin,Yanan Yang,Jing Qu et al.
Xiaojing Lin et al.
Objective: To investigate the influences of exercise on the levels of chemerin and its receptor chemokine-like receptor (CMKLR1) in the peripheral metabolic organs of obesity and diabetes rats, and whether the mechanism i...
Sex specific impact of different obesity phenotypes on the risk of incident hypertension: Tehran lipid and glucose study [0.03%]
不同肥胖表型对高血压发病风险的性别差异:泰斯兰脂质和葡萄糖研究
Maryam Kabootari,Samaneh Akbarpour,Fereidoun Azizi et al.
Maryam Kabootari et al.
Background: To investigate the association between different obesity phenotypes and the risk of incident hypertension among both genders. Methods: ...
Stingless bee honey protects against lipopolysaccharide induced-chronic subclinical systemic inflammation and oxidative stress by modulating Nrf2, NF-κB and p38 MAPK [0.03%]
stingless蜜蜂蜂蜜通过调节Nrf2、NF-κB和p38 MAPK保护lipopolysaccharide引起的慢性亚临床全身性炎症和氧化应激
Yazan Ranneh,Abdah Md Akim,Hasiah Ab Hamid et al.
Yazan Ranneh et al.
Background: Epidemiological and experimental studies have extensively indicated that chronic subclinical systemic inflammation (CSSI) and oxidative stress are risk factors for several chronic diseases, including cancer, a...
An adiponectin-S1P axis protects against lipid induced insulin resistance and cardiomyocyte cell death via reduction of oxidative stress [0.03%]
脂联素-S1P轴通过降低氧化应激对抗由血脂诱导的胰岛素抵抗和心肌细胞死亡
Amy Botta,Ying Liu,Sivaporn Wannaiampikul et al.
Amy Botta et al.
Background: Adiponectin exerts several beneficial cardiovascular effects, however their specific molecular mechanisms require additional understanding. This study investigated the mechanisms of adiponectin action in the h...
Dietary iron interacts with genetic background to influence glucose homeostasis [0.03%]
膳食铁与遗传背景相互作用影响葡萄糖稳态
Mario A Miranda,Celine L St Pierre,Juan F Macias-Velasco et al.
Mario A Miranda et al.
Background: Iron is a critical component of metabolic homeostasis, but consumption of dietary iron has increased dramatically in the last 30 years, corresponding with the rise of metabolic disease. While the link between ...
Role of PCK1 gene on oil tea-induced glucose homeostasis and type 2 diabetes: an animal experiment and a case-control study [0.03%]
PCK1基因在油茶调节糖代谢及2型糖尿病发病中的作用:动物实验和病例对照研究
Qiantu Hu,Huafeng Chen,Yanli Zuo et al.
Qiantu Hu et al.
Background: Oil tea is a type of traditional tea beverage used for treating various ailments in minority population in Guangxi, China. Our previous study showed oil tea improved glucose and lipid levels in type 2 diabetic...
Involvement of PPARγ/FSP27 in the pathogenic mechanism underlying insulin resistance: tipping the balance between lipogenesis and fat storage in adult catch-up growth rats [0.03%]
PPARγ/FSP27参与胰岛素抵抗发病机制的作用:调节成年追赶型生长大鼠脂质生成与脂质储存平衡的研究
Yan Li,Shan Yu,Lulu Chen et al.
Yan Li et al.
Background: Catch-up growth in adult (CUGA) is characterized by visceral fat accumulation, ectopic lipid deposition and insulin resistance (IR). Here, we investigated the determinants of these pathophysiological consequen...